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Research note
Nipun de Silva
General Sir John Kotelawala Defence University
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4467-3659
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Objectives:
To compare carriage rates of Staphylococcus aureus in patients with and without chronic kidney disease (CKD) and identify associated factors.
Results:
We enrolled 64 CKD (A-1 = 13, A-2 = 17, A-3 = 34) and 56 non-CKD controls (B). Patients were categorized as: stage 5 CKD on haemodialysis (A-1), stage 5 CKD not on haemodialysis (A-2), renal transplant recipients with glomerular filtration rate > 60 ml/min (A-3) and those having chronic medical diseases with glomerular filtration rate > 60 ml/min/m2 (B). Median age = 57 years (range = 17–77). Nasal or axillary Staphylococcus aureus carriage was seen in 5 (38.5%), 2 (11.8%), 5 (14.7%) and 9 (16.1%) patients from A-1 to A-3 and B groups respectively. All isolated organisms were methicillin sensitive. Haemodialysis (p = 0.035) and antibiotic use in the preceding month (p = 0.02) were associated with carriage. Demographic factors and co-morbidities were not associated with carriage.
Keywords
Staphylococcus aureus, chronic kidney disease, carriage
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This is a preprint. It has not completed peer review.
Research note
Nipun de Silva
General Sir John Kotelawala Defence University
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4467-3659
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 16 Jul, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Objectives:
To compare carriage rates of Staphylococcus aureus in patients with and without chronic kidney disease (CKD) and identify associated factors.
Results:
We enrolled 64 CKD (A-1 = 13, A-2 = 17, A-3 = 34) and 56 non-CKD controls (B). Patients were categorized as: stage 5 CKD on haemodialysis (A-1), stage 5 CKD not on haemodialysis (A-2), renal transplant recipients with glomerular filtration rate > 60 ml/min (A-3) and those having chronic medical diseases with glomerular filtration rate > 60 ml/min/m2 (B). Median age = 57 years (range = 17–77). Nasal or axillary Staphylococcus aureus carriage was seen in 5 (38.5%), 2 (11.8%), 5 (14.7%) and 9 (16.1%) patients from A-1 to A-3 and B groups respectively. All isolated organisms were methicillin sensitive. Haemodialysis (p = 0.035) and antibiotic use in the preceding month (p = 0.02) were associated with carriage. Demographic factors and co-morbidities were not associated with carriage.
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