1. Toshikuni N, Tsuchishima M, Fukumura A, Arisawa T, Tsutsumi M. Associations of Fatty Liver Disease with Hypertension, Diabetes, and Dyslipidemia: Comparison between Alcoholic and Nonalcoholic Steatohepatitis. Gastroenterology research and practice. 2017;2017:9127847-9127847. https://doi.org/10.1155/2017/9127847.
2. Sporea I, Popescu A, Dumitrascu D, Brisc C, Nedelcu L, Trifan A, Gheorghe L, Fierbinteanu Braticevici C. Nonalcoholic Fatty Liver Disease: Status Quo. J Gastrointestin Liver Dis. 2018;27(4):439-448. http://dx.doi.org/10.15403/jgld.2014.1121.274.quo.
3. Tilg H, Moschen AR, Roden M. NAFLD and diabetes mellitus. Nat Rev Gastroenterol Hepatol. 2017;14(1):32-42. https://doi.org/10.1038/nrgastro.2016.147.
4. Dyson JK, Anstee QM, McPherson S. Nonalcoholic fatty liver disease: a practical approach to diagnosis and staging. Frontline gastroenterology. 2014;5(3):211-218. https://doi.org/10.1136/flgastro-2013-100403.
5. Silaghi CA, Silaghi H, Colosi HA, Craciun AE, Farcas A, Cosma DT, Hancu N, Pais R, Georgescu CE. Prevalence and predictors of nonalcoholic fatty liver disease as defined by the fatty liver index in a type 2 diabetes population. Clujul medical (1957). 2016;89(1):82-88. https://doi.org/10.15386/cjmed-544.
6. Jimba S, Nakagami T, Takahashi M, Wakamatsu T, Hirota Y, Iwamoto Y, Wasada TJDM. Prevalence of nonalcoholic fatty liver disease and its association with impaired glucose metabolism in Japanese adults. 2005;22(9):1141-1145.
7. Fan J-G, Zhu J, Li X-J, Chen L, Li L, Dai F, Li F, Chen S-YJJoh. Prevalence of and risk factors for fatty liver in a general population of Shanghai, China. 2005;43(3):508-514.
8. Gupte P, Amarapurkar D, Agal S, Baijal R, Kulshrestha P, Pramanik S, Patel N, Madan A, Amarapurkar AJJog, hepatology. Nonalcoholic steatohepatitis in type 2 diabetes mellitus. 2004;19(8):854-858.
9. Tokita Y, Maejima Y, Shimomura K, Takenoshita S, Ishiyama N, Akuzawa M, Shimomura Y, Nakajima K. Non-alcoholic Fatty Liver Disease Is a Risk Factor for Type 2 Diabetes in Middle-aged Japanese Men and Women. Internal medicine (Tokyo, Japan). 2017;56(7):763-771. https://doi.org/10.2169/internalmedicine.56.7115.
10. Bril F, Cusi K. Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Diabetes Care. 2017;40(3):419-430. https://doi.org/10.2337/dc16-1787.
11. Busiello RA, Savarese S, Lombardi A. Mitochondrial uncoupling proteins and energy metabolism. Frontiers in physiology. 2015;6:36-36. https://doi.org/10.3389/fphys.2015.00036.
12. Xu H, Hertzel AV, Steen KA, Wang Q, Suttles J, Bernlohr DA. Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2. Molecular and cellular biology. 2015;35(6):1055-1065. https://doi.org/10.1128/MCB.01122-14.
13. Dalgaard LT, Andersen G, Larsen LH, Sørensen TI, Andersen T, Drivsholm T, Borch‐Johnsen K, Fleckner J, Hansen T, Din NJOr. Mutational analysis of the UCP2 core promoter and relationships of variants with obesity. 2003;11(11):1420-1427.
14. Saleh M, Wheeler M, Chan CBJD. Uncoupling protein-2: evidence for its function as a metabolic regulator. 2002;45(2):174-187.
15. Horvath B, Spies C, Horvath G, Kox WJ, Miyamoto S, Barry S, Warden CH, Bechmann I, Diano S, Heemskerk JJBp. Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold. 2002;64(3):369-374.
16. Jin X, Yu MS, Huang Y, Xiang Z, Chen YP. MiR-30e-UCP2 pathway regulates alcoholic hepatitis progress by influencing ATP and hydrogen peroxide expression. Oncotarget. 2017;8(38):64294-64302. https://doi.org/10.18632/oncotarget.19729.
17. Hazlehurst JM, Woods C, Marjot T, Cobbold JF, Tomlinson JW. Nonalcoholic fatty liver disease and diabetes. Metabolism: clinical and experimental. 2016;65(8):1096-1108. https://doi.org/10.1016/j.metabol.2016.01.001.
18. Yang L, Dong Z, Zhou J, Ma Y, Pu W, Zhao D, He H, Ji H, Yang Y, Wang X, et al. Common UCP2 variants contribute to serum urate concentrations and the risk of hyperuricemia. Sci Rep. 2016;6:27279. https://doi.org/10.1038/srep27279.
19. Pan H-C, Lee C-C, Chou K-M, Lu S-C, Sun C-Y. Serum levels of uncoupling proteins in patients with differential insulin resistance: A community-based cohort study. Medicine. 2017;96(40):e8053-e8053. https://doi.org/10.1097/MD.0000000000008053.
20. Marti A, Corbalan MS, Forga L, Martinez-Gonzalez MA, Martinez JA. Higher obesity risk associated with the exon-8 insertion of the UCP2 gene in a Spanish case-control study. Nutrition. 2004;20(6):498-501. https://doi.org/10.1016/j.nut.2004.03.019.
21. Chen L, Magliano DJ, Zimmet PZJNre. The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives. 2012;8(4):228.
22. Koehler EM, Schouten JN, Hansen BE, Hofman A, Stricker BH, Janssen HLJCG, Hepatology. External validation of the fatty liver index for identifying nonalcoholic fatty liver disease in a population-based study. 2013;11(9):1201-1204.
23. Trépo E, Valenti L. Update on NAFLD genetics: From new variants to the clinic. Journal of hepatology. 2020.
24. Mohammadi S, Farajnia S, Shadmand M, Mohseni F, Baghban R. Association of rs780094 polymorphism of glucokinase regulatory protein with nonalcoholic fatty liver disease. BMC Research Notes. 2020;13(1):26. https://doi.org/10.1186/s13104-020-4891-y.
25. Liu L, Zhao X, Kang S, Zhang DJG. An association between− 866G/A polymorphism in the promoter of UCP2 and obesity: a meta-analysis. 2013;514(1):41-47.
26. Qian L, Xu K, Xu X, Gu R, Liu X, Shan S, Yang TJPO. UCP2-866G/A, Ala55Val and UCP3-55C/T polymorphisms in association with obesity susceptibility—a meta-analysis study. 2013;8(4):e58939.
27. de Souza BM, Brondani LA, Boucas AP, Sortica DA, Kramer CK, Canani LH, Leitao CB, Crispim DJPo. Associations between UCP1-3826A/G, UCP2-866G/A, Ala55Val and Ins/Del, and UCP3-55C/T polymorphisms and susceptibility to type 2 diabetes mellitus: case-control study and meta-analysis. 2013;8(1):e54259.
28. Yu G, Wang J, Xu K, Dong J. Dynamic regulation of uncoupling protein 2 expression by microRNA-214 in hepatocellular carcinoma. Bioscience reports. 2016;36(3):e00335. https://doi.org/10.1042/BSR20160062.
29. Brondani LA, de Souza BM, Assmann TS, Boucas AP, Bauer AC, Canani LH, Crispim D. Association of the UCP polymorphisms with susceptibility to obesity: case-control study and meta-analysis. Mol Biol Rep. 2014;41(8):5053-5067. https://doi.org/10.1007/s11033-014-3371-7.
30. Mutombo PB, Yamasaki M, Shiwaku K. UCP2 I/D modulated change in BMI during a lifestyle modification intervention study in Japanese subjects. Genetic testing and molecular biomarkers. 2013;17(1):16-20. https://doi.org/10.1089/gtmb.2012.0229.
31. Wang X, Axelsson J, Nordfors L, Qureshi AR, Avesani C, Barany P, Schalling M, Heimbürger O, Lindholm B, Stenvinkel PJNDT. Changes in fat mass after initiation of maintenance dialysis is influenced by the uncoupling protein 2 exon 8 insertion/deletion polymorphism. 2006;22(1):196-202.
32. Lee YH, Kim W, Yu BC, Park BL, Kim LH, Shin HD. Association of the ins/del polymorphisms of uncoupling protein 2 (UCP2) with BMI in a Korean population. Biochem Biophys Res Commun. 2008;371(4):767-771. https://doi.org/10.1016/j.bbrc.2008.04.144.
33. Brondani LA, Assmann TS, de Souza BM, Boucas AP, Canani LH, Crispim D. Meta-analysis reveals the association of common variants in the uncoupling protein (UCP) 1-3 genes with body mass index variability. PLoS One. 2014;9(5):e96411. https://doi.org/10.1371/journal.pone.0096411.
34. Hashemi M, Rezaei H, Kaykhaei MA, Taheri M. A 45-bp insertion/deletion polymorphism of UCP2 gene is associated with metabolic syndrome. J Diabetes Metab Disord. 2014;13(1):12. https://doi.org/10.1186/2251-6581-13-12.
35. Gul A, Ates O, Ozer S, Kasap T, Ensari E, Demir O, Sonmezgoz E. Role of the Polymorphisms of Uncoupling Protein Genes in Childhood Obesity and Their Association with Obesity-Related Disturbances. Genet Test Mol Biomarkers. 2017;21(9):531-538. https://doi.org/10.1089/gtmb.2017.0068.
36. Sreedhar A, Zhao Y. Uncoupling protein 2 and metabolic diseases. Mitochondrion. 2017;34:135-140.
37. Bouillaud F, Alves-Guerra M-C, Ricquier D. UCPs, at the interface between bioenergetics and metabolism. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2016;1863(10):2443-2456. https://doi.org/10.1016/j.bbamcr.2016.04.013.
38. Papazoglou D, Papathanasiou P, Papanas N, Papatheodorou K, Chatziangeli E, Nikitidis I, Kotsiou S, Maltezos E. Uncoupling protein-2 45-base pair insertion/deletion polymorphism: is there an association with severe obesity and weight loss in morbidly obese subjects? Metab Syndr Relat Disord. 2012;10(4):307-311. https://doi.org/10.1089/met.2012.0003.
39. Zhang M, Wang M, Zhao Z-T. Uncoupling protein 2 gene polymorphisms in association with overweight and obesity susceptibility: A meta-analysis. Meta Gene. 2014;2:143-159.
40. Plomin R, Deary IJ. Genetics and intelligence differences: five special findings. Molecular psychiatry. 2015;20(1):98-108. https://doi.org/10.1038/mp.2014.105.
41. Huang T, Shu Y, Cai Y-D. Genetic differences among ethnic groups. BMC genomics. 2015;16:1093-1093. https://doi.org/10.1186/s12864-015-2328-0.