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Research
Louncény Fatoumata Barry
Neurosurgery Department Fann Teaching Hospital, Dakar, Senegal
Corresponding Author
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Background
lung cancer is the first mortality cause by cancer around the world. Bones metastasis occurrence is a common eventuality in case of lung cancer (40% at the diagnosis). In order to evaluate the indications and measure the effectiveness of surgery in the management of PBC spinal metastases, we report a series of 52 patients.
Methods
During 6 years, from January 2009 to December 2014 at the Neurosurgery Unit of Marseille North Hospital (France), we studied retrospectively 52 patients records, who underwent a surgery for spinal metastasis of lung cancer. The study was only about patients which metastases were surgically treated. We used Stata software for the computation, and concerning the linear regression, all values under 0.1 were considered significant.
Results
the average age was 63.6 years (39–80 years) with a sex ratio of 3. Non-small cell lung cancer was the most common, ie 36 cases (69.2%). Rachialgia associated to vertebral fracture with medullar compression was the most common clinical presentation (31 cases or 59.6%). SINS score (spinal instability neoplastic score) was equal or above 7 in 41 cases (78.9%). The general condition (Karnofski) was medium in 35 cases (67.4%). Survival prediction beyond 12 months was null according to Tokuhashi Index. The surgical indication was essentially palliative. Evolution was characterised by painful symptomatology regression in 44 cases (84.6%), stabilization of initially unstable lesion and motor deficit improvement in 48.3 % of cases. The average survival time following the surgery was 16 months.
Conclusion
Our results show the interest of surgery for pain relief and spinal stabilization in patient with spinal metastasis of lung cancer, and the relativity of predictive survival score.
Keywords
cancer, bronchopulmonary, metastasis, spine
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This is a preprint. It has not completed peer review.
Research
Louncény Fatoumata Barry
Neurosurgery Department Fann Teaching Hospital, Dakar, Senegal
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 12 Apr, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
lung cancer is the first mortality cause by cancer around the world. Bones metastasis occurrence is a common eventuality in case of lung cancer (40% at the diagnosis). In order to evaluate the indications and measure the effectiveness of surgery in the management of PBC spinal metastases, we report a series of 52 patients.
Methods
During 6 years, from January 2009 to December 2014 at the Neurosurgery Unit of Marseille North Hospital (France), we studied retrospectively 52 patients records, who underwent a surgery for spinal metastasis of lung cancer. The study was only about patients which metastases were surgically treated. We used Stata software for the computation, and concerning the linear regression, all values under 0.1 were considered significant.
Results
the average age was 63.6 years (39–80 years) with a sex ratio of 3. Non-small cell lung cancer was the most common, ie 36 cases (69.2%). Rachialgia associated to vertebral fracture with medullar compression was the most common clinical presentation (31 cases or 59.6%). SINS score (spinal instability neoplastic score) was equal or above 7 in 41 cases (78.9%). The general condition (Karnofski) was medium in 35 cases (67.4%). Survival prediction beyond 12 months was null according to Tokuhashi Index. The surgical indication was essentially palliative. Evolution was characterised by painful symptomatology regression in 44 cases (84.6%), stabilization of initially unstable lesion and motor deficit improvement in 48.3 % of cases. The average survival time following the surgery was 16 months.
Conclusion
Our results show the interest of surgery for pain relief and spinal stabilization in patient with spinal metastasis of lung cancer, and the relativity of predictive survival score.
Figure 1
Figure 2
Figure 3
Figure 4
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