1. Xiong B, Shi Q, Fang H. Dexmedetomidine alleviates postoperative cognitive dysfunction by inhibiting neuron excitation in aged rats. Am J Transl Res. 2016; 8(1): 70-80. PMID: 27069541.
2. Norkienė I, Samalavičius R, Misiūrienė I, Paulauskienė K, Budrys V, Ivaškevičius J. Incidence and risk factors for early postoperative cognitive decline after coronary artery bypass grafting. Medicina (Kaunas). 2010; 46(7): 460-464. PMID: 20966618.
3. Besch G, Vettoretti L, Claveau M, Boichut N, Mahr N, Bouhake Y, Liu N, Chazot T, Samain E, Pili-Floury S. Early post-operative cognitive dysfunction after closed-loop versus manual target controlled-infusion of propofol and remifentanil in patients undergoing elective major non-cardiac surgery: Protocol of the randomized controlled single-blind POCD-ELA trial. Medicine (Baltimore). 2018; 97(40): e12558. https://doi.org/ 10.1097/MD.0000000000012558.
4. Zhu H, Liu W, Fang H. Inflammation caused by peripheral immune cells across into injured mouse blood brain barrier can worsen postoperative cognitive dysfunction induced by isoflurane. BMC Cell Biol. 2018; 19(1): 23. https://doi.org/10.1186/s12860-018-0172-1.
5. Zhang M, Zhang YH, Fu HQ, Zhang QM, Wang TL. Ulinastatin May Significantly Improve Postoperative Cognitive Function of Elderly Patients Undergoing Spinal Surgery by Reducing the Translocation of Lipopolysaccharide and Systemic Inflammation. Front Pharmacol. 2018; 9: 1007. https://doi.org/ 10.3389/fphar.2018.01007.
6. Cao Y, Li Z, Ma L, Ni C, Li L, Yang N, Shi C, Guo X. Isoflurane‑induced postoperative cognitive dysfunction is mediated by hypoxia‑inducible factor‑1α‑dependent neuroinflammation in aged rats. Mol Med Rep. 2018; 17(6): 7730-7736. https://doi.org/10.3892/mmr.2018.8850.
7. Danielson M, Reinsfelt B, Westerlind A, Zetterberg H, Blennow K, Ricksten SE. Effects of methylprednisolone on blood-brain barrier and cerebral inflammation in cardiac surgery-a randomized trial. J Neuroinflammation. 2018; 15(1): 283. https://doi.org/10.1186/s12974-018-1318-y.
8. Zila I, Mokra D, Kopincova J, Kolomaznik M, Javorka M, Calkovska A. Vagal-immune interactions involved in cholinergic anti-inflammatory pathway. Physiol Res. 2017; 66(Supplementum 2): S139-S145. PMID: 28937230.
9. Bonaz B, Sinniger V, Pellissier S. Vagus Nerve Stimulation at the Interface of Brain-Gut Interactions. Cold Spring Harb Perspect Med. 2018. https://doi.org/10.1101/cshperspect.a034199
10. Borovikova LV, Ivanova S, Zhang M, Yang H, Botchkina GI, Watkins LR, Wang H, Abumrad N, Eaton JW, Tracey KJ. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature. 2000; 405(6785): 458-62. https://doi.org/10.1038/35013070.
11. Johnson RL, Wilson CG. A review of vagus nerve stimulaton as a therapeutic intervention. J Inflamm Res. 2018; 11: 203-2123. https://doi.org/10.2147/JIR.S163248.
12. Li Z, Liu X, Zhang Y, Shi J, Zhang Y, Xie P, Yu T. Connection changes in somatosensory cortex induced by different doses of propofol. PLoS One. 2014; 9(2): e87829. https://doi.org/10.1371/journal.pone.0087829.
13. Lee SW, Kulkarni K, Annoni EM, Libbus I, KenKnight BH, Tolkacheva EG. Stochastic vagus nerve stimulation affects acute heart rate dynamics in rats. PLoS One. 2018; 13(3): e0194910. https://doi.org/10.1371/journal.pone.0194910.
14. Stauss HM. Differential hemodynamic and respiratory responses to right and left cervical vagal nerve stimulation in rats. Physiol Rep. 2017; 5(7): pii: e13244. https://doi.org/10.14814/phy2.13244
15. Broncel A, Bocian R, Kłos-Wojtczak P, Konopacki J. Medial septal cholinergic mediation of hippocampal theta rhythm induced by vagal nerve stimulation. PLoS One. 2018; 13(11): e0206532. https://doi.org/10.1371/journal.pone.0206532
16. Stauss HM, Stangl H, Clark KC, Kwitek AE, Lira VA. Cervical vagal nerve stimulation impairs glucose tolerance and suppresses insulin release in conscious rats. Physiol Rep. 2018 Dec;6(24):e13953. https://doi.org/10.14814/phy2.13953.
17. Cao J, Lu KH, Powley TL, Liu Z. Vagal nerve stimulation triggers widespread responses and alters large-scale functional connectivity in the rat brain. PLoS One. 2017; 12(12): e0189518. https://doi.org/10.1371/journal.pone.0189518.
18. Livak KJ1, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25(4): 402-408. https://doi.org/10.1006/meth.2001.1262
19. Xin X, Xin F, Chen X, Zhang Q, Li Y, Huo S, Chang C, Wang Q. Hypertonic saline for prevention of delirium in geriatric patients who underwent hip surgery. J Neuroinflammation. 2017; 14(1): 221. https://doi.org/10.1186/s12974-017-0999-y
20. Nadelson MR, Sanders RD, Avidan MS. Perioperative cognitive trajectory in adults. Br J Anaesth. 2014; 112(3): 440-51. https://doi.org/10.1093/bja/aet420
21. Kalliolias GD, Ivashkiv LB. TNF biology, pathogenic mechanisms and emerging therapeutic strategies. Nat Rev Rheumatol. 2016; 12(1): 49-62. https://doi.org/10.1038/nrrheum.2015.169.
22. Hua FZ, Ying J, Zhang J, Wang XF, Hu YH, Liang YP, Liu Q, Xu GH. Naringenin pre-treatment inhibits neuroapoptosis and ameliorates cognitive impairment in rats exposed to isoflurane anesthesia by regulating the PI3/Akt/PTEN signalling pathway and suppressing NF-κB-mediated inflammation. Int J Mol Med. 2016; 38(4): 1271-1280. https://doi.org/10.3892/ijmm.2016.2715.
23. Zheng JW, Meng B, Li XY, Lu B, Wu GR, Chen JP. NF-κB/P65 signaling pathway: a potential therapeutic target in postoperative cognitive dysfunction after sevoflurane anesthesia. Eur Rev Med Pharmacol Sci. 2017; 21(2): 394-407. PMID: 28165545.
24. Bonaz B, Sinniger V, Pellissier S. Anti-inflammatory properties of the vagus nerve: potential therapeutic implications of vagus nerve stimulation. J Physiol. 2016; 594(20): 5781-5790. https://doi.org/10.1113/JP271539.
25. Huffman WJ, Subramaniyan S, Rodriguiz RM, Wetsel WC, Grill WM, Terrando N. Modulation of neuroinflammation and memory dysfunction using percutaneous vagus nerve stimulation in mice. Brain Stimul. 2019; 12(1): 19-29. https://doi.org/10.1016/j.brs.2018.10.005.
26. Maurer SV, Williams CL. The Cholinergic System Modulates Memory and Hippocampal Plasticity via Its Interactions with Non-Neuronal Cells. Front Immunol. 2017; 8: 1489. https://doi.org/10.3389/fimmu.2017.01489.
27. Zhou JP, Wang F, Li RL, Yuan BL, Guo YL. Effects of febrile seizure on motor, behavior, spatial learning and memory in rats. Zhonghua Er Ke Za Zhi. 2004, 42(1): 49-53. PMID: 14990108. Chinese.
28. Liu RP, Fang JL, Rong PJ, Zhao Y, Meng H, Ben H, Li L, Huang ZX, Li X, Ma YG, Zhu B. Effects of electroacupuncture at auricular concha region on the depressive status of unpredictable chronic mild stress rat models. Evid Based Complement Alternat Med. 2013; 2013: 789674. https://doi.org/10.1155/2013/789674.
29. Liu AF, Zhao FB, Wang J, Lu YF, Tian J, Zhao Y, Gao Y, Hu XJ, Liu XY, Tan J, Tian YL, Shi J. Effects of vagus nerve stimulation on cognitive functioning in rats with cerebral ischemia reperfusion. J Transl Med. 2016; 14: 101. https://doi.org/10.1186/s12967-016-0858-0.
30. Zhu YZ, Yao R, Zhang Z, Xu H, Wang LW. Parecoxib prevents early postoperative cognitive dysfunction in elderly patients undergoing total knee arthroplasty: A double-blind, randomized clinical consort study. Medicine (Baltimore). 2016; 95(28):e4082. https://doi.org/10.1097/MD.0000000000004082.
31. Chen K, Wei P, Zheng Q, Zhou J, Li J. Neuroprotective effects of intravenous lidocaine on early postoperative cognitive dysfunction in elderly patients following spine surgery. Med Sci Monit. 2015; 21:1402-1407. https://doi.org/10.12659/MSM.894384.
32. Pappa M, Theodosiadis N, Tsounis A, Sarafis P. Pathogenesis and treatment of post-operative cognitive dysfunction. Electron Physician. 2017; 9(2): 3768-3775. https://doi.org/10.19082/3768.