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Research Article
Jyh-Horng Chen
Department of Electrical Engineering, National Taiwan University
Corresponding Author
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Latest simultaneous multi-slice (SMS) methods greatly benefit MR efficiency for recent studies using parallel imaging technique. However, these methods are limited by the requirement of array coils. The proposed Coherent Wideband method, which employs an extended field of view to separate multiple excited slices, can be applied to any existing MRI instrument, even those without array coils. In this study, the Coherent Wideband echo-planar imaging method was implemented on 7T animal MRI to exhibit comprehensive enhancements in neuro-architecture, including diffusion tensor imaging (DTI) and functional MR studies (fMRI). Under the same scan time, the time-saving effect can be manipulated to increase the number of averages for DTI SNR improvement, reducing fractional anisotropy difference by 56.9% (from 0.072 to 0.041) and the deviation angle by 64% (from 25.3⁰ to 16.2⁰). In summary, Coherent Wideband EPI will provide faster, higher resolution, thinner slice, or higher SNR imaging for precision neuro-architecture studies.
Keywords
Latest simultaneous multi-slice (SMS) methods, parallel imaging technique, precision neuro-architecture studies
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No competing interests reported.
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CURRENT STATUS: Under Review
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Posted 01 Jun, 2021
No community comments so far
Editorial decision: Major revision
On 04 Aug, 2021
Reviews received
Received 04 Aug, 2021
Reviews received
Received 02 Aug, 2021
Reviewers agreed
On 19 Jul, 2021
Reviewers invited
Invitations sent on 18 Jul, 2021
Editor assigned
On 18 Jul, 2021
Editor invited
On 25 May, 2021
Submission checks complete
On 25 May, 2021
First submitted
On 14 May, 2021
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Electrical Engineering
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This preprint is under consideration at Scientific Reports. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Jyh-Horng Chen
Department of Electrical Engineering, National Taiwan University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 2
Posted 01 Jun, 2021
No community comments so far
Editorial decision: Major revision
On 04 Aug, 2021
Reviews received
Received 04 Aug, 2021
Reviews received
Received 02 Aug, 2021
Reviewers agreed
On 19 Jul, 2021
Reviewers invited
Invitations sent on 18 Jul, 2021
Editor assigned
On 18 Jul, 2021
Editor invited
On 25 May, 2021
Submission checks complete
On 25 May, 2021
First submitted
On 14 May, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Electrical Engineering
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Latest simultaneous multi-slice (SMS) methods greatly benefit MR efficiency for recent studies using parallel imaging technique. However, these methods are limited by the requirement of array coils. The proposed Coherent Wideband method, which employs an extended field of view to separate multiple excited slices, can be applied to any existing MRI instrument, even those without array coils. In this study, the Coherent Wideband echo-planar imaging method was implemented on 7T animal MRI to exhibit comprehensive enhancements in neuro-architecture, including diffusion tensor imaging (DTI) and functional MR studies (fMRI). Under the same scan time, the time-saving effect can be manipulated to increase the number of averages for DTI SNR improvement, reducing fractional anisotropy difference by 56.9% (from 0.072 to 0.041) and the deviation angle by 64% (from 25.3⁰ to 16.2⁰). In summary, Coherent Wideband EPI will provide faster, higher resolution, thinner slice, or higher SNR imaging for precision neuro-architecture studies.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Figure 9
Figure 10
Figure 11
Figure 12
Figure 13
Figure 14
Figure 15
Figure 16
Figure 17
Figure 18
No competing interests reported.
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