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Research Article
Xiaomei Guo
Huazhong University of Science and Technology
Corresponding Author
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NT-proBNP was much lower than the recommended threshold for heart failure in some adult COVID-19 inpatients with poor prognosis. NT-proBNP has different ranges of normal values for different age groups. NT-proBNP levels specific to age, defined as NT-proBNP ratio, were divided into quartiles and measured the hazard ratios (and 95% confidence intervals) for in-hospital death of COVID-19 patients. Higher NT-proBNP ratio was directly associated, in a dose-response manner, with a higher risk of all causes in-hospital death in the COVID-19 patients. Our study shows that NT-proBNP ratio is an independent predictor of the risk of in-hospital death of the adult patients with COVID-19. This implies that NT-proBNP levels specific to age in the COVID-19 patietns requires attention of healthcare workers.
Keywords
SARS-CoV-2 infection, COVID-19, NT-proBNP
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No competing interests reported.
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A new preprint design is coming!
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research Article
Xiaomei Guo
Huazhong University of Science and Technology
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 03 May, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Infectious Diseases
License:
This work is licensed under a CC BY 4.0 License. Read Full License
NT-proBNP was much lower than the recommended threshold for heart failure in some adult COVID-19 inpatients with poor prognosis. NT-proBNP has different ranges of normal values for different age groups. NT-proBNP levels specific to age, defined as NT-proBNP ratio, were divided into quartiles and measured the hazard ratios (and 95% confidence intervals) for in-hospital death of COVID-19 patients. Higher NT-proBNP ratio was directly associated, in a dose-response manner, with a higher risk of all causes in-hospital death in the COVID-19 patients. Our study shows that NT-proBNP ratio is an independent predictor of the risk of in-hospital death of the adult patients with COVID-19. This implies that NT-proBNP levels specific to age in the COVID-19 patietns requires attention of healthcare workers.
Figure 1
Figure 2
Figure 3
No competing interests reported.
This is a list of supplementary files associated with this preprint. Click to download.
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