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Research article
Hao Liu
Corresponding Author
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Background: To investigate the effect of the difference in the C2-7 angle (C2-7A) on dysphagia after anterior cervical discectomy and fusion (ACDF) with the Zero-P Implant System.
Methods: A retrospective analysis of 181 patients who underwent ACDF with the Zero-P Implant System and had at least one year of follow-up was performed from January 2011 to November 2018. All patients were divided into a non-dysphagia group and a dysphagia group to explore the effect of the difference between postoperative and preoperative C2-7As (dC2-7A) on postoperative dysphagia. Furthermore, other possible related factors including the difference between postoperative and preoperative O-C2 angles (dO-C2A), sex, age, body mass index (BMI), intraoperative time, estimated blood loss, diabetes mellitus, hypertension, smoking, alcohol consumption, prevertebral soft-tissue swelling (PSTS), the highest segment involved in the surgery and the levels of surgical segments were analyzed.
Results: One hundred thirty-nine patients were included in the non-dysphagia group, and 42 patients were included in the dysphagia group. Single-factor analysis showed that smoking, PSTS and the dC2-7A were significantly different between the two groups (P<0.05). Spearman’s correlation coefficient showed no significant correlation between the degree of dysphagia and he dC2-7A (P>0.05). The results of multiple-factor analysis with an ordinal logistic regression model showed that smoking, PSTS and the dC2-7A were significantly associated with the incidence of dysphagia (P<0.05).
Conclusions: The postoperative C2-7A has an important effect on the occurrence of dysphagia in patients undergoing interbody fusion surgery with the Zero-P Implant System.
Keywords
Dysphagia, Zero-P, Cervical vertebrae, Related factors
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CURRENT STATUS: Published
View the published article at BMC Musculoskeletal Disorders.
No community comments so far
Submission checks complete
On 07 Oct, 2020
Editorial decision: Accept
On 29 Sep, 2020
Editor assigned
On 27 Sep, 2020
Editor invited
On 27 Sep, 2020
No comments provided
Reviewer #2 agreed
On 20 Sep, 2020
Reviewers invited
Invitations sent on 17 Sep, 2020
Reviewer #1 agreed
On 17 Sep, 2020
Editor assigned
On 10 Sep, 2020
Submission checks complete
On 09 Sep, 2020
Editor invited
On 09 Sep, 2020
Version 1
Posted 15 Jul, 2020
No comments provided
Editorial decision: Major revision
On 22 Aug, 2020
Review #2 received
Received 20 Aug, 2020
Review #1 received
Received 28 Jul, 2020
Reviewer #1 agreed
On 25 Jul, 2020
Reviewer #2 agreed
On 25 Jul, 2020
Reviewers invited
Invitations sent on 16 Jul, 2020
Editor assigned
On 13 Jul, 2020
Submission checks complete
On 12 Jul, 2020
Editor invited
On 12 Jul, 2020
First submitted
On 11 Jul, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedics
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A new preprint design is coming!
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See the published version of this preprint at BMC Musculoskeletal Disorders.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Hao Liu
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Musculoskeletal Disorders.
No community comments so far
Submission checks complete
On 07 Oct, 2020
Editorial decision: Accept
On 29 Sep, 2020
Editor assigned
On 27 Sep, 2020
Editor invited
On 27 Sep, 2020
No comments provided
Reviewer #2 agreed
On 20 Sep, 2020
Reviewers invited
Invitations sent on 17 Sep, 2020
Reviewer #1 agreed
On 17 Sep, 2020
Editor assigned
On 10 Sep, 2020
Submission checks complete
On 09 Sep, 2020
Editor invited
On 09 Sep, 2020
Version 1
Posted 15 Jul, 2020
No comments provided
Editorial decision: Major revision
On 22 Aug, 2020
Review #2 received
Received 20 Aug, 2020
Review #1 received
Received 28 Jul, 2020
Reviewer #1 agreed
On 25 Jul, 2020
Reviewer #2 agreed
On 25 Jul, 2020
Reviewers invited
Invitations sent on 16 Jul, 2020
Editor assigned
On 13 Jul, 2020
Submission checks complete
On 12 Jul, 2020
Editor invited
On 12 Jul, 2020
First submitted
On 11 Jul, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Musculoskeletal Disorders.
Background: To investigate the effect of the difference in the C2-7 angle (C2-7A) on dysphagia after anterior cervical discectomy and fusion (ACDF) with the Zero-P Implant System.
Methods: A retrospective analysis of 181 patients who underwent ACDF with the Zero-P Implant System and had at least one year of follow-up was performed from January 2011 to November 2018. All patients were divided into a non-dysphagia group and a dysphagia group to explore the effect of the difference between postoperative and preoperative C2-7As (dC2-7A) on postoperative dysphagia. Furthermore, other possible related factors including the difference between postoperative and preoperative O-C2 angles (dO-C2A), sex, age, body mass index (BMI), intraoperative time, estimated blood loss, diabetes mellitus, hypertension, smoking, alcohol consumption, prevertebral soft-tissue swelling (PSTS), the highest segment involved in the surgery and the levels of surgical segments were analyzed.
Results: One hundred thirty-nine patients were included in the non-dysphagia group, and 42 patients were included in the dysphagia group. Single-factor analysis showed that smoking, PSTS and the dC2-7A were significantly different between the two groups (P<0.05). Spearman’s correlation coefficient showed no significant correlation between the degree of dysphagia and he dC2-7A (P>0.05). The results of multiple-factor analysis with an ordinal logistic regression model showed that smoking, PSTS and the dC2-7A were significantly associated with the incidence of dysphagia (P<0.05).
Conclusions: The postoperative C2-7A has an important effect on the occurrence of dysphagia in patients undergoing interbody fusion surgery with the Zero-P Implant System.
Figure 1
Figure 2
Figure 3
Figure 4
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