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Research article
Ten-Fang Yang
National Chiao Tung University College of Biological Science and Technology
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background:
The symptoms of acute ankle anterior talofibular ligament (ATFL) partial tear includes pain, swelling, and range of motion limitation. Local steroid injection can provide strong anti-inflammatory effect. The aim of the study is to evaluate the effectiveness and complications of local steroid injection for acute ATFL partial tear in short term.
Materials and Methods:
This is a prospective randomized study. Forty patients with acute isolated ATFL partial tear diagnosed by sonography were equally separated into two groups. The steroid group received 1cc Diprospan local injection whereas the control group received 1cc normal saline injection. We used sonography to check the tendon rupture status before injection, 6 weeks and 12 weeks after injection. We also used American Orthopaedic Foot & Ankle Society (AOFAS) score and Pain Visual Analogue Scale (VAS) score to evaluate the function and pain before injection, 1 week, 3 weeks, 6 weeks, and 12 weeks after injection. Student t test was used to compare the statistically significant difference between groups.
Result:
There was no deteriorating of ATFL tear found by sonography in both groups until 12 weeks. The average AOFAS score was higher than 80 after 1 weeks in steroid group while the score was higher than 80 after 3 weeks in control group. AOFAS score was significantly higher in steroid group for the first 3 weeks after injection (p = 3.2x10-7 and 0.022, at 1 week and 3 weeks respectively), but there was no significant difference between groups afterward. VAS score was significant higher in steroid group only in the first week (p = 0.0073) and there was no significant difference between groups afterward
Conclusion:
Steroid local injection can safely shorten the period of functional disability and relieve pain for acute ATFL partial tear in short term.
Trial registration:
ChiCTR, ChiCTR2000029629, registered 07 February 2020
http://www.chictr.org.cn/showproj.aspx?proj=49198
Keywords
Steroid, local injection, anterior talofibular ligament, partial tear
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A new preprint design is coming!
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research article
Ten-Fang Yang
National Chiao Tung University College of Biological Science and Technology
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 11 Aug, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background:
The symptoms of acute ankle anterior talofibular ligament (ATFL) partial tear includes pain, swelling, and range of motion limitation. Local steroid injection can provide strong anti-inflammatory effect. The aim of the study is to evaluate the effectiveness and complications of local steroid injection for acute ATFL partial tear in short term.
Materials and Methods:
This is a prospective randomized study. Forty patients with acute isolated ATFL partial tear diagnosed by sonography were equally separated into two groups. The steroid group received 1cc Diprospan local injection whereas the control group received 1cc normal saline injection. We used sonography to check the tendon rupture status before injection, 6 weeks and 12 weeks after injection. We also used American Orthopaedic Foot & Ankle Society (AOFAS) score and Pain Visual Analogue Scale (VAS) score to evaluate the function and pain before injection, 1 week, 3 weeks, 6 weeks, and 12 weeks after injection. Student t test was used to compare the statistically significant difference between groups.
Result:
There was no deteriorating of ATFL tear found by sonography in both groups until 12 weeks. The average AOFAS score was higher than 80 after 1 weeks in steroid group while the score was higher than 80 after 3 weeks in control group. AOFAS score was significantly higher in steroid group for the first 3 weeks after injection (p = 3.2x10-7 and 0.022, at 1 week and 3 weeks respectively), but there was no significant difference between groups afterward. VAS score was significant higher in steroid group only in the first week (p = 0.0073) and there was no significant difference between groups afterward
Conclusion:
Steroid local injection can safely shorten the period of functional disability and relieve pain for acute ATFL partial tear in short term.
Trial registration:
ChiCTR, ChiCTR2000029629, registered 07 February 2020
http://www.chictr.org.cn/showproj.aspx?proj=49198
Figure 1
Figure 2
This is a list of supplementary files associated with this preprint. Click to download.
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