Background: Asymptomatic intracranial aneurysms rupture without any warning, therefore, use of high-resolution imaging techniques for the rupture risk assessment is essential.
Methods: This study’s goal is to assess the feasibility of scanning acoustic microscopy (SAM) in the characterization of cerebral aneurysm. The aneurysm’s dome samples were obtained from 12 different patients with and without subarachnoid hemorrhage.
Results: The acoustic impedance values are found statistically higher in samples from female patients than in samples from male patients. On the other hand, sample from a male patient without subarachnoid hemorrhage has higher acoustic impedance value when compared with samples from male patients with subarachnoid hemorrhage, however, this discrepancy is not observed in female patients.
Conclusion: In summary, the success of SAM in monitoring the altering acoustic impedance values in male and female patients with and without subarachnoid hemorrhage indicates the potential of SAM for the diagnosis of instability of cerebral aneurysms.