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Research Article
Dileep Kumar
National Institute of Cardiovascular Diseases
Corresponding Author
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Background: Non ST segment elevation myocardial infarction (NSTEMI) is a clinical condition characterized by typical symptoms of myocardial ischemia along with electrocardiographic changes and a positive value of troponin. After presentation in emergency department these patients have their troponin I value and electrocardiography done. The echocardiography should also be performed in these patients. This study was conducted to determine the relationship between ECG, Echo and troponin and how prognostically these are relevant to each other along with their prognostic significance.
Results: This observational study was conducted at tertiary care cardiac hospital on 221 patients diagnosed with the NSTEMI. The most frequent finding on presenting ECG was ST depression in anterior leads (V1-V6) in 27.6%. Median troponin I at presentation was 3.2 ng/dl and median ejection fraction was 45%. Overall all-cause mortality rate at 6-months was observed to be 8.6%, re-infarction in 5%, re-hospitalization in 16.3%, and heart failure in 25.3% was observed. However, mortality was higher for patients with baseline ECG findings of A-fib, generalized ST-depression , poor R-wave progression, Wellens sign, and T-wave inversion in inferior also mortality rate was relatively higher among patients with poor (<30%) LVEF.
Conclusion: ECG and Echocardiography were prognostically significant and correlated better at 6 months. However Troponin lacks the association and prognostic significance at 6 months.
Keywords
troponin, patients, mortality, myocardial, infarction, nstemi
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This preprint is under consideration at SN Comprehensive Clinical Medicine. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Dileep Kumar
National Institute of Cardiovascular Diseases
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 22 Jun, 2021
No community comments so far
Reviewers invited
Invitations sent on 20 Jun, 2021
First submitted
On 16 Apr, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Non ST segment elevation myocardial infarction (NSTEMI) is a clinical condition characterized by typical symptoms of myocardial ischemia along with electrocardiographic changes and a positive value of troponin. After presentation in emergency department these patients have their troponin I value and electrocardiography done. The echocardiography should also be performed in these patients. This study was conducted to determine the relationship between ECG, Echo and troponin and how prognostically these are relevant to each other along with their prognostic significance.
Results: This observational study was conducted at tertiary care cardiac hospital on 221 patients diagnosed with the NSTEMI. The most frequent finding on presenting ECG was ST depression in anterior leads (V1-V6) in 27.6%. Median troponin I at presentation was 3.2 ng/dl and median ejection fraction was 45%. Overall all-cause mortality rate at 6-months was observed to be 8.6%, re-infarction in 5%, re-hospitalization in 16.3%, and heart failure in 25.3% was observed. However, mortality was higher for patients with baseline ECG findings of A-fib, generalized ST-depression , poor R-wave progression, Wellens sign, and T-wave inversion in inferior also mortality rate was relatively higher among patients with poor (<30%) LVEF.
Conclusion: ECG and Echocardiography were prognostically significant and correlated better at 6 months. However Troponin lacks the association and prognostic significance at 6 months.
Figure 1
Figure 2
Figure 3
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