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Research Article
Mehrdad Bouyeh
Islamic Azad University Rasht Branch
Corresponding Author
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This study was performed to investigate the effect of different levels of aspirin on the diet of broilers. The experiment was conducted in a completely randomized design using 120 one-day-old male broiler chicks of commercial Ross 308 strain to study the effects of three different levels of aspirin (0, 50 and 100 mg/kg) in 3 treatments, in 4 replicates, each including 10 chicks, during 42 days. The effects of different levels of aspirin, added to a basic diet, on performance, carcass characteristics and digestive organs, blood plasma components, liver enzymes, immune system, secal microflora, and acid profile of breast meat of broiler chickens were investigated. Data analysis was performed by SAS statistical software and the comparison of the means with Duncan's multiple-range test at 5% probability level. The results showed that in the final period, the chickens fed by a diet containing 100 mg/kg of aspirin (A) had the highest feed intake and weight gain and the best feed conversion ratio compared to the other treatments. Also, according to the tables, the lowest production cost and the best European factor were related to treatment A100, which was statistically significant compared to the control (P < 0.05). In addition, the use of the same level of aspirin resulted in a significant increase in some carcass properties and a decrease in ventricular fat compared to the control (P < 0.05). On the other hand, the effects of using two different levels of aspirin on blood parameters and liver enzymes of broilers except for alkaline phosphatase were not significant throughout the period (P ≥ 0.05). Also, the use of the same level of aspirin had no significant effect on the function of the humoral immune system in response to antigen injection, antibody titer against sheep red blood cells (SRBC) and antibody titer against Newcastle disease and influenza virus (P ≥ 0.05). But according to the table, the highest percentage of neutrophils and eosinophils was related to this treatment. Also, aspirin treatments increased the levels of unsaturated fatty acids and decreased saturated fatty acids. Moreover, aspirin treatment led to a reduction in the population of Escherichia coli. So, based on the results of the present study, the use of 100 mg/kg aspirin in the diet of broilers is recommended.
Keywords
acetylsalicylic acid, immune system, performance, blood parameters, fatty acid profile
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This is a preprint. It has not completed peer review.
Research Article
Mehrdad Bouyeh
Islamic Azad University Rasht Branch
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 28 Apr, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
This study was performed to investigate the effect of different levels of aspirin on the diet of broilers. The experiment was conducted in a completely randomized design using 120 one-day-old male broiler chicks of commercial Ross 308 strain to study the effects of three different levels of aspirin (0, 50 and 100 mg/kg) in 3 treatments, in 4 replicates, each including 10 chicks, during 42 days. The effects of different levels of aspirin, added to a basic diet, on performance, carcass characteristics and digestive organs, blood plasma components, liver enzymes, immune system, secal microflora, and acid profile of breast meat of broiler chickens were investigated. Data analysis was performed by SAS statistical software and the comparison of the means with Duncan's multiple-range test at 5% probability level. The results showed that in the final period, the chickens fed by a diet containing 100 mg/kg of aspirin (A) had the highest feed intake and weight gain and the best feed conversion ratio compared to the other treatments. Also, according to the tables, the lowest production cost and the best European factor were related to treatment A100, which was statistically significant compared to the control (P < 0.05). In addition, the use of the same level of aspirin resulted in a significant increase in some carcass properties and a decrease in ventricular fat compared to the control (P < 0.05). On the other hand, the effects of using two different levels of aspirin on blood parameters and liver enzymes of broilers except for alkaline phosphatase were not significant throughout the period (P ≥ 0.05). Also, the use of the same level of aspirin had no significant effect on the function of the humoral immune system in response to antigen injection, antibody titer against sheep red blood cells (SRBC) and antibody titer against Newcastle disease and influenza virus (P ≥ 0.05). But according to the table, the highest percentage of neutrophils and eosinophils was related to this treatment. Also, aspirin treatments increased the levels of unsaturated fatty acids and decreased saturated fatty acids. Moreover, aspirin treatment led to a reduction in the population of Escherichia coli. So, based on the results of the present study, the use of 100 mg/kg aspirin in the diet of broilers is recommended.
This is a list of supplementary files associated with this preprint. Click to download.
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