Sex differences in an Italian pediatric population covid-19 positive
Background: Since December 2019 coronavirus disease (COVID-19) emerged in Wuhan and spread rapidly worldwide. Despite the high number of people affected, data on clinical features and prognostic factors in children and adolescents are limited. We propose a retrospective study aimed to evaluate clinical characteristics of children infected with SARS-CoV-2 in Italy.
Methods: A pediatric population admitted with COVID-19 to Bambino Gesù Children's Hospital of Rome (Italy) in the period from the end of February to May 2020 has been studied taking into account gender. Medical history, comorbidities, symptoms and laboratory findings were obtained from patients' electronic medical records.
Results: In 41 patients (21 males and 20 females) we found that: i) fever and cough were the dominant symptoms, while gastrointestinal symptoms were rare; and ii) all ages of childhood were susceptible to COVID-19. Moreover, we found that females with COVID-19, were significantly
(p = 0.04) older than males and required more days of hospitalization (p = 0.01).
Moreover, compared to females, a greater number of males had high values of C reactive protein (3 males vs 1 female) and erythrocyte sedimentation rate (2 males vs 1 female).
Conclusions: Compared to the adults we found that COVID-19 infection in children is a non-severe inflammatory disease in both males and females. In any case, many detailed studies should be conducted.
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Sex differences in an Italian pediatric population covid-19 positive
Posted 13 Jan, 2021
On 04 Jan, 2021
On 03 Jan, 2021
Invitations sent on 03 Jan, 2021
On 03 Jan, 2021
Received 03 Jan, 2021
Received 03 Jan, 2021
On 01 Jan, 2021
On 01 Jan, 2021
On 01 Jan, 2021
On 18 Nov, 2020
Received 17 Nov, 2020
On 11 Nov, 2020
Received 11 Nov, 2020
On 10 Nov, 2020
Invitations sent on 10 Nov, 2020
On 10 Nov, 2020
On 10 Nov, 2020
On 10 Nov, 2020
On 30 Sep, 2020
Received 17 Sep, 2020
On 14 Sep, 2020
Received 13 Sep, 2020
On 10 Sep, 2020
On 10 Sep, 2020
Received 30 Jul, 2020
On 21 Jul, 2020
Invitations sent on 20 Jul, 2020
On 16 Jul, 2020
On 15 Jul, 2020
On 15 Jul, 2020
On 15 Jul, 2020
Background: Since December 2019 coronavirus disease (COVID-19) emerged in Wuhan and spread rapidly worldwide. Despite the high number of people affected, data on clinical features and prognostic factors in children and adolescents are limited. We propose a retrospective study aimed to evaluate clinical characteristics of children infected with SARS-CoV-2 in Italy.
Methods: A pediatric population admitted with COVID-19 to Bambino Gesù Children's Hospital of Rome (Italy) in the period from the end of February to May 2020 has been studied taking into account gender. Medical history, comorbidities, symptoms and laboratory findings were obtained from patients' electronic medical records.
Results: In 41 patients (21 males and 20 females) we found that: i) fever and cough were the dominant symptoms, while gastrointestinal symptoms were rare; and ii) all ages of childhood were susceptible to COVID-19. Moreover, we found that females with COVID-19, were significantly
(p = 0.04) older than males and required more days of hospitalization (p = 0.01).
Moreover, compared to females, a greater number of males had high values of C reactive protein (3 males vs 1 female) and erythrocyte sedimentation rate (2 males vs 1 female).
Conclusions: Compared to the adults we found that COVID-19 infection in children is a non-severe inflammatory disease in both males and females. In any case, many detailed studies should be conducted.