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Research Article
Clemens Spink
University Medical Center Hamburg-Eppendorf
Corresponding Author
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Purpose: To compare the patient radiation doses during angiographic selective adrenal vein sampling (AVS) before and after a noise reduction imaging technology upgrade.
Methods: In this retrospective single-center-study, cumulative air kerma (AK), cumulative dose area product (DAP), fluoroscopy time and contrast agent dosage were recorded from 70 patients during AVS. 35 procedures were performed before and 35 after a noise reduction imaging processing technology upgrade. Mean values were calculated and compared using an unpaired student’s t-test. DSA image quality was assessed independently by two blinded readers using a four-point Likert scale (1=poor; 4=excellent) and compared using Wilcoxon signed-rank test.
Results: After the technology upgrade we observed a significant reduction of 35% in AK (1.7±0.7 vs. 1.1±0.7 Gy, p=0.01) and a significant reduction of 28% in DAP (235.1±113 vs. 170.1±94 Gy*cm2, p=0.01) in comparison to procedures before the upgrade. There were no significant differences between the number of exposure frames (143±86 vs. 132±61frames, p=0.53), fluoroscopy time (42±23 vs. 36±18 min, p=0.22), or the amount of contrast medium used (179.5±84 vs. 198.1±109 ml, p=0.41). There was also no significant difference regarding image quality (3 (2-4) vs. 3 (2-4), p=0.67).
Conclusion: The angiographic noise reduction imaging technology upgrade significantly decreases the radiation dose during adrenal vein sampling without increasing time of fluoroscopy or contrast volume and without compromising image quality.
Keywords
Adrenal vein sampling, radiation dose, image-processing technology, interventional radiology, angiography
Figure 1
Figure 2
Competing interest reported. Michael Grass and Thomas Schmidt are employees of Philips. All other authors don't have any competing interests/conflict of interest to declare.
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CURRENT STATUS: Under Revision
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On 30 Nov, 2021
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Received 29 Nov, 2021
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On 23 Jul, 2021
Reviewers invited
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A new preprint design is coming!
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This preprint is under consideration at Scientific Reports. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Clemens Spink
University Medical Center Hamburg-Eppendorf
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Revision
Version 1
Posted 07 May, 2021
No community comments so far
Editorial decision: Major revision
On 30 Nov, 2021
Reviews received
Received 29 Nov, 2021
Reviewers agreed
On 29 Oct, 2021
Reviews received
Received 05 Aug, 2021
Reviewers agreed
On 23 Jul, 2021
Reviewers invited
Invitations sent on 14 May, 2021
Editor assigned
On 14 May, 2021
Editor invited
On 07 May, 2021
Submission checks complete
On 05 May, 2021
First submitted
On 21 Apr, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Purpose: To compare the patient radiation doses during angiographic selective adrenal vein sampling (AVS) before and after a noise reduction imaging technology upgrade.
Methods: In this retrospective single-center-study, cumulative air kerma (AK), cumulative dose area product (DAP), fluoroscopy time and contrast agent dosage were recorded from 70 patients during AVS. 35 procedures were performed before and 35 after a noise reduction imaging processing technology upgrade. Mean values were calculated and compared using an unpaired student’s t-test. DSA image quality was assessed independently by two blinded readers using a four-point Likert scale (1=poor; 4=excellent) and compared using Wilcoxon signed-rank test.
Results: After the technology upgrade we observed a significant reduction of 35% in AK (1.7±0.7 vs. 1.1±0.7 Gy, p=0.01) and a significant reduction of 28% in DAP (235.1±113 vs. 170.1±94 Gy*cm2, p=0.01) in comparison to procedures before the upgrade. There were no significant differences between the number of exposure frames (143±86 vs. 132±61frames, p=0.53), fluoroscopy time (42±23 vs. 36±18 min, p=0.22), or the amount of contrast medium used (179.5±84 vs. 198.1±109 ml, p=0.41). There was also no significant difference regarding image quality (3 (2-4) vs. 3 (2-4), p=0.67).
Conclusion: The angiographic noise reduction imaging technology upgrade significantly decreases the radiation dose during adrenal vein sampling without increasing time of fluoroscopy or contrast volume and without compromising image quality.
Figure 1
Figure 2
Competing interest reported. Michael Grass and Thomas Schmidt are employees of Philips. All other authors don't have any competing interests/conflict of interest to declare.
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