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Research article
Fariborz Moazami
Shiraz University of Medical Sciences
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3035-2926
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: This study aims to evaluate the ability of sodium thiosulfate (STS) to neutralize the adverse effect of sodium hypochlorite (NaOCl) on dentin micro-hardness.
Methods: Fifty single-rooted teeth were longitudinally sectioned. The samples divided into a control and four sample groups (n = 20). All the samples were immersed in different solutions as follows, Control: Normal saline for 15 min, G1and G2: 2.5% NaOCl for 15 min, G3: 2.5% NaOCl for 15 min, followed by 5% STS for 10 min, G4: Normal saline for 15 min followed by 5% STS for 10 min. All groups except G1 incubated for one week before the test. The micro-hardness of samples was measured. Data were analyzed using the Kruskal-Wallis test for pairwise comparisons. A p-value < 0.05 was considered significant.
Results: All groups showed a significant decrease in the micro-hardness value compared with the control group. NaOCl for one week (G2) reduced the micro-hardness of dentine compared with samples, tested immediately after immersion in NaOCl (G1) (p < 0.05). NaOCl alone (G2) or treated with STS (G3) resulted in a significant decrease in micro-hardness compared with the STS group (G4) (p < 0.05).
Conclusions: STS as a neutralizing agent could not prevent the dentin micro-hardness downturn caused by NaOCl.
Keywords
dentin, micro-hardness tests, sodium hypochlorite, sodium thiosulfate
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View the published article at BMC Oral Health.
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Posted 12 Nov, 2020
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On 09 Nov, 2020
Editorial decision: Accept
On 05 Nov, 2020
No comments provided
Editorial decision: Minor revision
On 28 Oct, 2020
Editor assigned
On 26 Oct, 2020
Submission checks complete
On 25 Oct, 2020
Editor invited
On 25 Oct, 2020
Version (no preprint)
Posted 05 Aug, 2020
Editorial decision: Major revision
On 21 Oct, 2020
Editor assigned
On 20 Oct, 2020
Submission checks complete
On 19 Oct, 2020
Editor invited
On 19 Oct, 2020
This version was not preprinted
No comments provided
Editorial decision: Major revision
On 15 Sep, 2020
Review #1 received
Received 07 Sep, 2020
Review #2 received
Received 04 Sep, 2020
Reviewer #2 agreed
On 30 Aug, 2020
Reviewer #1 agreed
On 19 Aug, 2020
Reviewers invited
Invitations sent on 03 Aug, 2020
Editor assigned
On 24 Jul, 2020
First submitted
On 23 Jul, 2020
Submission checks complete
On 23 Jul, 2020
Editor invited
On 23 Jul, 2020
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A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
See the published version of this preprint at BMC Oral Health.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Fariborz Moazami
Shiraz University of Medical Sciences
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3035-2926
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Oral Health.
Version 3
Posted 12 Nov, 2020
No community comments so far
Submission checks complete
On 09 Nov, 2020
Editorial decision: Accept
On 05 Nov, 2020
No comments provided
Editorial decision: Minor revision
On 28 Oct, 2020
Editor assigned
On 26 Oct, 2020
Submission checks complete
On 25 Oct, 2020
Editor invited
On 25 Oct, 2020
Version (no preprint)
Posted 05 Aug, 2020
Editorial decision: Major revision
On 21 Oct, 2020
Editor assigned
On 20 Oct, 2020
Submission checks complete
On 19 Oct, 2020
Editor invited
On 19 Oct, 2020
This version was not preprinted
No comments provided
Editorial decision: Major revision
On 15 Sep, 2020
Review #1 received
Received 07 Sep, 2020
Review #2 received
Received 04 Sep, 2020
Reviewer #2 agreed
On 30 Aug, 2020
Reviewer #1 agreed
On 19 Aug, 2020
Reviewers invited
Invitations sent on 03 Aug, 2020
Editor assigned
On 24 Jul, 2020
First submitted
On 23 Jul, 2020
Submission checks complete
On 23 Jul, 2020
Editor invited
On 23 Jul, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Oral Health.
Background: This study aims to evaluate the ability of sodium thiosulfate (STS) to neutralize the adverse effect of sodium hypochlorite (NaOCl) on dentin micro-hardness.
Methods: Fifty single-rooted teeth were longitudinally sectioned. The samples divided into a control and four sample groups (n = 20). All the samples were immersed in different solutions as follows, Control: Normal saline for 15 min, G1and G2: 2.5% NaOCl for 15 min, G3: 2.5% NaOCl for 15 min, followed by 5% STS for 10 min, G4: Normal saline for 15 min followed by 5% STS for 10 min. All groups except G1 incubated for one week before the test. The micro-hardness of samples was measured. Data were analyzed using the Kruskal-Wallis test for pairwise comparisons. A p-value < 0.05 was considered significant.
Results: All groups showed a significant decrease in the micro-hardness value compared with the control group. NaOCl for one week (G2) reduced the micro-hardness of dentine compared with samples, tested immediately after immersion in NaOCl (G1) (p < 0.05). NaOCl alone (G2) or treated with STS (G3) resulted in a significant decrease in micro-hardness compared with the STS group (G4) (p < 0.05).
Conclusions: STS as a neutralizing agent could not prevent the dentin micro-hardness downturn caused by NaOCl.
Figure 1
Figure 2
Figure 3
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