Kabi-Gebro area is located within the Abay Basin at Dera District of North Shewa Zone near Gundomeskel town in the Central highland of Ethiopia and it is about 320 Km from Addis Ababa. This is characterized by undulating topography, intense rainfall, active erosion and highly cultivated area. Geologically characterized by weathered sedimentary and volcanic rocks. Currently, landslides are creating serious challenges in road construction, farming practices and affecting people in this area. Active landslides in this area damaged the gravel road, houses and agricultural land. The main objective of this research is to prepare the landslide susceptibility map. To overcome the landslide problem in this area, landslide susceptibility map was prepared using GIS- based Weights of Evidence model. Based on detailed field assessment and Google Earth image interpretation, 514 landslide locations were identified and classified randomly as training landslide (80%) and validation landslide (20%). The training landslide data set include nine landslide causative factors such as lithology, slope angle, aspect, curvature, land use/land cover, distance to stream, distance to lineament, distance to spring and rainfall inorder to prepare landslide susceptibility map in this study. The landslide susceptibility maps were prepared by adding the weights of contrast values of the nine causative factors using rater calculator in the spatial analyst tool of ArcGIS. The final landslide susceptibility map was reclassified as very low, low, moderate, high and very high landslide susceptiblity classes. This susceptibility map was validated using landslide density index and Area Under the Curve (AUC). The result from this validation showed a success rate and avalidaton rate accuracies of 82.4% and 83.4% respectively for this model. Finally, this study recommends application of appropriate mitigation or corrective measures in order to lessen the impact of landslide in the area.