See the published version of this preprint at Journal of Cardiothoracic Surgery.
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Case report
Dan Han
The First Affiliated Hospital of Xi'an Jiaotong University
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Quadricuspid aortic valve (QAV) is a rare congenital heart defect usually accompanied with different hemodynamic abnormalities. Due to the rarity of QAV, treatment and prognosis of QAV patients with aortic regurgitation still remain challenging. We here present the first case of a patient with severe QAV regurgitation who underwent successful treatment and performed favorable prognosis with transapical aortic valve implantation (TAVI) using J-Valve system.
Case presentation: A 62-year-old man experienced intermittent palpitation, shortness of breath and chest pain. Echocardiography revealed congenital QAV with massive aortic regurgitation and mild aortic stenosis, left ventricular enlargement. Aortic valve replacement was successfully performed with TAVI using J-Valve system. The postoperation and follow-up was uneventful.
Conclusion: Transapical aortic valve implantation (TAVI) using J-Valve system has emerged as a new high success rate method for treatment of high-risk patients with simple non-calcified aortic valve insufficiency.
Keywords
Quadricuspid aortic valve, Transapical aortic valve implantation, Case report
Figure 1
Figure 2
Figure 3
This is a list of supplementary files associated with this preprint. Click to download.
- CAREchecklist.pdf
- SupplFigure1.tif
Supplemental Figure1: Cardiac computed tomography (CCT) revealed type A QAV without significant valvular thickening or calcification, average aortic annulus diameter was 25.9 mm ( Panel A), average left ventricular outflow tract diameter was 28.2 mm ( Panel B), sinus of valsalva diameters were 33.1 mm and 31.8 mm ( Panel C), sinotubular junction was 28.8 mm ( Panel D), ascending aortic diameter was 31.8 mm ( Panel E), the left coronary ostial height was 11.5 mm ( Panel F), the right coronary ostial height was 14.7 mm ( Panel G), and the angle between the left ventricular outflow tract and apex was 147° ( Panel H).
- SupplV1.mp4
Supplemental video 1: TEE revealed congenital type A QAV.
- SupplV2.mp4
Supplemental video 2: The fluoroscopy showed a pigtail catheter was inserted into the aortic sinus and a temporary pacemaker was implanted to the right ventricular apex.
- SupplV3.mp4
Supplemental video 3: The fluoroscopy showed that super-stiff guidewire was placed into the abdominal aorta and did not affect mitral valve tendinous cord.
- SupplV4.mp4
Supplemental video 4: The fluoroscopy showed that the three “U-shape” graspers were carefully folded as three “long elliptical shape” in favor of positioning and then totally released into the left-, right- and non-coronary sinuses to clamp the native leaflets.
- SupplV5.mp4
Supplemental video 5: The fluoroscopy showed that the valve was delivered into the annular plan guided by the graspers and released.
- SupplV6.mp4
Supplemental video 6: The aortic root angiography showed a good valve stent position, and the artificial aortic valve worked well with patent coronaries.
- SupplV7.mp4
Supplemental video 7: TEE showed no aortic regurgitation and no paravalvular leak from the view of long axis.
- SupplV8.mp4
Supplemental video 8: TEE showed no aortic regurgitation and no paravalvular leak from the view of short axis.
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CURRENT STATUS: Published
View the published article at Journal of Cardiothoracic Surgery.
Version 1
Posted 07 May, 2021
No community comments so far
Editorial decision: Major revision
On 25 Jun, 2021
Review #2 received
Received 20 Jun, 2021
Review #3 received
Received 10 Jun, 2021
Reviewer #3 agreed
On 09 Jun, 2021
Reviewer #2 agreed
On 07 Jun, 2021
Review #1 received
Received 07 Jun, 2021
Reviews received
Received 07 Jun, 2021
Reviewers invited
Invitations sent on 07 Jun, 2021
Reviewer #1 agreed
On 06 Jun, 2021
Editor assigned
On 27 Apr, 2021
Submission checks complete
On 27 Apr, 2021
Editor invited
On 27 Apr, 2021
First submitted
On 27 Apr, 2021
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A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
See the published version of this preprint at Journal of Cardiothoracic Surgery.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Case report
Dan Han
The First Affiliated Hospital of Xi'an Jiaotong University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Journal of Cardiothoracic Surgery.
Version 1
Posted 07 May, 2021
No community comments so far
Editorial decision: Major revision
On 25 Jun, 2021
Review #2 received
Received 20 Jun, 2021
Review #3 received
Received 10 Jun, 2021
Reviewer #3 agreed
On 09 Jun, 2021
Reviewer #2 agreed
On 07 Jun, 2021
Review #1 received
Received 07 Jun, 2021
Reviews received
Received 07 Jun, 2021
Reviewers invited
Invitations sent on 07 Jun, 2021
Reviewer #1 agreed
On 06 Jun, 2021
Editor assigned
On 27 Apr, 2021
Submission checks complete
On 27 Apr, 2021
Editor invited
On 27 Apr, 2021
First submitted
On 27 Apr, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Journal of Cardiothoracic Surgery.
Background: Quadricuspid aortic valve (QAV) is a rare congenital heart defect usually accompanied with different hemodynamic abnormalities. Due to the rarity of QAV, treatment and prognosis of QAV patients with aortic regurgitation still remain challenging. We here present the first case of a patient with severe QAV regurgitation who underwent successful treatment and performed favorable prognosis with transapical aortic valve implantation (TAVI) using J-Valve system.
Case presentation: A 62-year-old man experienced intermittent palpitation, shortness of breath and chest pain. Echocardiography revealed congenital QAV with massive aortic regurgitation and mild aortic stenosis, left ventricular enlargement. Aortic valve replacement was successfully performed with TAVI using J-Valve system. The postoperation and follow-up was uneventful.
Conclusion: Transapical aortic valve implantation (TAVI) using J-Valve system has emerged as a new high success rate method for treatment of high-risk patients with simple non-calcified aortic valve insufficiency.
Figure 1
Figure 2
Figure 3
This is a list of supplementary files associated with this preprint. Click to download.
- CAREchecklist.pdf
- SupplFigure1.tif
Supplemental Figure1: Cardiac computed tomography (CCT) revealed type A QAV without significant valvular thickening or calcification, average aortic annulus diameter was 25.9 mm ( Panel A), average left ventricular outflow tract diameter was 28.2 mm ( Panel B), sinus of valsalva diameters were 33.1 mm and 31.8 mm ( Panel C), sinotubular junction was 28.8 mm ( Panel D), ascending aortic diameter was 31.8 mm ( Panel E), the left coronary ostial height was 11.5 mm ( Panel F), the right coronary ostial height was 14.7 mm ( Panel G), and the angle between the left ventricular outflow tract and apex was 147° ( Panel H).
- SupplV1.mp4
Supplemental video 1: TEE revealed congenital type A QAV.
- SupplV2.mp4
Supplemental video 2: The fluoroscopy showed a pigtail catheter was inserted into the aortic sinus and a temporary pacemaker was implanted to the right ventricular apex.
- SupplV3.mp4
Supplemental video 3: The fluoroscopy showed that super-stiff guidewire was placed into the abdominal aorta and did not affect mitral valve tendinous cord.
- SupplV4.mp4
Supplemental video 4: The fluoroscopy showed that the three “U-shape” graspers were carefully folded as three “long elliptical shape” in favor of positioning and then totally released into the left-, right- and non-coronary sinuses to clamp the native leaflets.
- SupplV5.mp4
Supplemental video 5: The fluoroscopy showed that the valve was delivered into the annular plan guided by the graspers and released.
- SupplV6.mp4
Supplemental video 6: The aortic root angiography showed a good valve stent position, and the artificial aortic valve worked well with patent coronaries.
- SupplV7.mp4
Supplemental video 7: TEE showed no aortic regurgitation and no paravalvular leak from the view of long axis.
- SupplV8.mp4
Supplemental video 8: TEE showed no aortic regurgitation and no paravalvular leak from the view of short axis.
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