In most manufacturing and assembly industries, such as automotive, aerospace, and nuclear power plants, it is critical to inspect the integrity of the used parts and components to avoid possible system failure for safety and quality control reasons. In addition, an unexpected failure causes extra costs due to the additional costs of maintenance, reparations, or even service delivery delays. Therefore, building an automated inspection system using industrial testing techniques such as Non-Destructive Testing (NDT) using X-ray computerized tomography (CT) is highly recommended. This paper proposes a Hybrid Defect Detection (HyDD) to automate the inspection process and improve defect detection accuracy. The proposed framework investigates incorporating deep learning and image processing techniques to enhance inspection performance and build an adaptive inspection system. The proposed method is validated using a real X-ray CT dataset with different types of defect scenarios. The results show that the proposed method could detect most defects and achieve up to 88% of the average detection rate. The proposed framework could be extended to defect-type recognition using object detection or semantic segmentation deep learning models.