Ethics approval and consent to participate and for publication
This study, the privacy and confidentially of the protocols and recruitment were approved by the plenary of the Research Ethics Committee of our institution (Comité de Ética de la Investigación Provincial de Málaga del 27 de abril de 2017) and conducted according to the guidelines instated by the Ethical Principles for Medical Research Involving Human Subjects adopted in the Declaration of Helsinki by the World Medical Association (64th WMA General Assembly, Fortaleza, Brazil, October 2013), Recommendation No. R (97) 5 of the Committee of Ministers to Member States on the Protection of Medical Data (1997), and European data protection act (Ley Orgánica del Parlamento Europeo y del Consejo de 27 de abril de 2016 de Protección de Datos, RGDP). All collected data were assigned numerical codes for privacy and confidentiality. Written informed consent was obtained from all patients in this study.
Availability of data and material
Not applicable
Competing interest
None
Fundings
This work has been funded by Sociedad Médica Andaluza de Adicciones y Patologías Médicas Asociadas (SOMAPA) and supported by Research Project funded by Consejería de Salud y Bienestar Social, Junta de Andalucía-Fundación Progreso y Salud (PI-0140-2018). NGM holds a Sara Borrell research contract (CD19/00019) funded by Instituto de Salud Carlos III (ISC-III) and European Regional Development Funds-European Union (ERDF-EU).
Author’s contributions
JJR and JMM were responsible for the study concept and design. NGM performed statistical analysis and interpretation of findings and drafted the manuscript. JJR and JMM coordinated the recruitment of participants. The ASG contributed to the acquisition of socio-demographic and psychiatric data by means of interviews and generated the database. All authors critically reviewed content and approved final version for publication.
Acknowledgements
The authors are grateful to The ANDOPIO Study Group for their valuable assistance throughout the clinical part of the study. All authors critically reviewed the content and approved final version for publication:
Aguilera Peralta G.1, Alaminos l.1, Cáceres Jerez C.1, Navarro González J.L.1, Rodríguez Rodríguez A.1, Suárez Márquez. C.1, Bernal Jimenez L.2, Corbalán Guerrero C.2, Crespo Jimenez Y.2, Diosdado Fernández J.2, Girón García S.2, Gómez Tortosa R.2, Jiménez Barea F.J.2, Lobo Lara M.J.2, Luque Pérez F.2, Rodríguez Melgar M. J.2, Roquete Castro J.L.2, Sánchez Pérez J.A.2, Seijo Ceballos P.2, Valdayo Boza M.J.2, Alcántara López F.C.3, Castro Granados M.G.3, Chacón Villafranca R.3, De la Fuente Darder B.3, Lizaur Barbudo M.3, Manchado López L.3, Moreno López R.3, Moya Mejías A.3, Castillo Fernández G.M.4, Joya Redondo J.4, Jurado De Flores Yepez G.4, López Callejas C.4, Orozco Carreras L.4, Ruiz Martínez M.4, Sánchez Viñas A.M.4 ,Álvarez García M.5, Bozquez Gómez I.5, Conseglieri Ponce C.5, De Mula Duran M.D.5, Gegundez Arias E.5, González Regalado J.5, Morales Rojas D.5, Ramírez López J.F.5, Gil Martínez A.6, Herrera Benítez F.6,Montanet Fernández E.6, Navarro Cabrera H.6, Rodríguez Rus S.6, Andújar Pérez C.7, Bravo López F.7, Burgos Bravo I.7, Campos Cloute R.7, Campos Gómez R.7, Founier López R.7, Galán Ruiz de la Herranz A.7, Gardeta Sabater P.7, Gómez Villaespesa Mará F.7, Guerrero Florido A.7, Luque García F.7, Martín de la Hinojosa J.M.7, Moreno Arrebola A.7, Pretel Pretel J.7, Torroba Molina J.7, Vázquez García F.7, Segura Zamudio J.A.7, Baena B.8, Cartagena E.8, Claro E.8, Iglesias Azcue C.8, López A.8, Morera A.8, Osuna P.8, Rodríguez Á.8, Sánchez C.8, Torres I.8, Velo L.8, Villafuerte V.8, Vázquez M.M.8
1 Servicio Provincial de Drogodependencias, Almeria, Spain
2 Servicio Provincial de Drogodependencias, Cádiz, Spain
3 Servicio Provincial de Drogodependencias, Córdoba, Spain
4 Servicio Provincial de Drogodependencias, Granada, Spain
5 Servicio Provincial de Drogodependencias, Huelva, Spain
6 Servicio Provincial de Drogodependencias, Jaen, Spain
7 Servicio Provincial de Drogodependencias, Málaga, Spain
8 Servicio Provincial de Drogodependencias, Sevilla, Spain