See the published version of this preprint at Journal of Cardiothoracic Surgery.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
Case report
Yiming Ni
Department of Cardio-Thoracic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China
Corresponding Author
ORCiD: https://orcid.org/0000-0002-2909-6734
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Pulmonary arteriovenous malformations are uncommon conditions of abnormal communications between pulmonary arteries and veins, which are most commonly congenital in nature. Although such condition is not extremely rare, it is an challenge in the differential diagnosis of pulmonary problems such as hypoxemia and pulmonary lesions.
Case presentation: We report a meaningful case of a 23-year-old male presented with elevated hemoglobin (23.0 g/dl) on admission. Physical examination revealed cyanosis, digital clubbing and low oxygen saturation on room air. The patient was initially diagnosed as polycythemia vera while the subsequent result of bone marrow aspiration was negative. During further assessment, pulmonary arteriovenous malformations were detected by computed tomographic angiography of pulmonary artery. Lobectomy was successfully performed with significant increase of oxygen saturation from 86% to 98%. The patient received an uneventful postoperative recovery and was followed up for nearly 5 years without recurrence.
Conclusions: Pulmonary arteriovenous malformations should be suspected in the patients with central cyanosis, digital clubbing, polycythemia and pulmonary lesion and without cardiac malformations. Embolization or surgery is highly recommended to reduce the risks caused by pulmonary arteriovenous malformations.
Keywords
Pulmonary arteriovenous malformation, Polycythemia, Cyanosis, Digital clubbing
Figure 1
This is a list of supplementary files associated with this preprint. Click to download.
Loading...
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Journal of Cardiothoracic Surgery.
No community comments so far
Editorial decision: Accept
On 20 Sep, 2020
Editor assigned
On 08 Sep, 2020
Submission checks complete
On 07 Sep, 2020
Editor invited
On 07 Sep, 2020
Version 1
Posted 30 Jul, 2020
No comments provided
Editorial decision: Major revision
On 23 Aug, 2020
Review #3 received
Received 16 Aug, 2020
Review #1 received
Received 10 Aug, 2020
Review #2 received
Received 10 Aug, 2020
Reviewer #3 agreed
On 04 Aug, 2020
Reviewer #1 agreed
On 03 Aug, 2020
Reviewer #2 agreed
On 03 Aug, 2020
Reviewers invited
Invitations sent on 01 Aug, 2020
First submitted
On 27 Jul, 2020
Editor assigned
On 27 Jul, 2020
Submission checks complete
On 26 Jul, 2020
Editor invited
On 26 Jul, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Cardiothoracic Surgery
Learn more about our company.
A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
See the published version of this preprint at Journal of Cardiothoracic Surgery.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Case report
Yiming Ni
Department of Cardio-Thoracic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China
Corresponding Author
ORCiD: https://orcid.org/0000-0002-2909-6734
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Journal of Cardiothoracic Surgery.
No community comments so far
Editorial decision: Accept
On 20 Sep, 2020
Editor assigned
On 08 Sep, 2020
Submission checks complete
On 07 Sep, 2020
Editor invited
On 07 Sep, 2020
Version 1
Posted 30 Jul, 2020
No comments provided
Editorial decision: Major revision
On 23 Aug, 2020
Review #3 received
Received 16 Aug, 2020
Review #1 received
Received 10 Aug, 2020
Review #2 received
Received 10 Aug, 2020
Reviewer #3 agreed
On 04 Aug, 2020
Reviewer #1 agreed
On 03 Aug, 2020
Reviewer #2 agreed
On 03 Aug, 2020
Reviewers invited
Invitations sent on 01 Aug, 2020
First submitted
On 27 Jul, 2020
Editor assigned
On 27 Jul, 2020
Submission checks complete
On 26 Jul, 2020
Editor invited
On 26 Jul, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Cardiothoracic Surgery
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Journal of Cardiothoracic Surgery.
Background: Pulmonary arteriovenous malformations are uncommon conditions of abnormal communications between pulmonary arteries and veins, which are most commonly congenital in nature. Although such condition is not extremely rare, it is an challenge in the differential diagnosis of pulmonary problems such as hypoxemia and pulmonary lesions.
Case presentation: We report a meaningful case of a 23-year-old male presented with elevated hemoglobin (23.0 g/dl) on admission. Physical examination revealed cyanosis, digital clubbing and low oxygen saturation on room air. The patient was initially diagnosed as polycythemia vera while the subsequent result of bone marrow aspiration was negative. During further assessment, pulmonary arteriovenous malformations were detected by computed tomographic angiography of pulmonary artery. Lobectomy was successfully performed with significant increase of oxygen saturation from 86% to 98%. The patient received an uneventful postoperative recovery and was followed up for nearly 5 years without recurrence.
Conclusions: Pulmonary arteriovenous malformations should be suspected in the patients with central cyanosis, digital clubbing, polycythemia and pulmonary lesion and without cardiac malformations. Embolization or surgery is highly recommended to reduce the risks caused by pulmonary arteriovenous malformations.
Figure 1
This is a list of supplementary files associated with this preprint. Click to download.
Loading...