There are many clinical studies on the relationship between obesity and DAA-THA, they put forward many different viewpoints[28–35]. However, there is still no unified conclusion on whether obesity have a negative impact on total hip arthroplasty. This is conflicting evidence as to whether, how and to what degree obesity may negatively influence outcomes of the total hip arthroplasty. For a more in-depth discussion, we have provided this idea as to whether there is a factor closely related to obesity but not absolutely consistent that leads to this result. Our prospective study explores the factor of AO to prove it.
Our research identified no significant differences between AO and non-AO patients in terms of their hip pain nor hip function 1 year following their THA, the preoperative scores of the two groups were significantly improved. There was no significant difference between the two groups of acetabular anteversion, inclination and patients’ satisfaction. However, there was a significant difference in the improvement of walking ability between the two groups. The improvement of walking ability in non-AO group was significantly higher than that in AO group. In terms of walking ability, AO has a certain impact on patients after THA. This is the same as Samantha Haebich's conclusion[7] on the impact of obesity on THA in 2019. This seems to corroborate the hypothesis proposed in this article. The relationship between AO index and degree of influence has not been discussed in depth in this study. The patient mentioned in the results who underwent revision surgery due to prosthesis infection was in non-AO group, the cause may be intraoperative infection. There was no significant difference in BMI between the two groups in this study, and the influence of obesity on the experimental results was ruled out.
A study by Purcell in 2016 showed that the infection rate of deep and superficial wounds in obese patients increased during DAA surgery[36]. In this study, there was no significant relationship between the occurrence of infection and AO, which seems to indicate that the increase in the infection rate in obese patients is not related to AO. But it is worth noting that the surgical method used direct anterior approach with a specific surgical auxiliary machine. During the operation, we took some measures on the abdomen of patients with AO to reduce the influence of abdominal fat on the operation and prevent it from affecting the surgical field of vision. This may be the reason why we have fewer complications.
In a large cohort study[37] of 124368 patients undergoing THA, the authors found that in patients undergoing total hip replacement surgery, obesity increased the risk of various complications and correction rate. For overall complications, 1-year revision surgery, and 90-day surgery complications, the risk increases with increasing body mass index (BMI). In a prospective study, Chee et al.[38]compared the matching of 55 consecutive THAs in morbidly obese patients with a set of 55 THAs in non-obese patients. The authors found that the incidence of all types of complications was significantly higher. However, there was no significant difference in the risk of superficial and deep wound infection and dislocation between the two group[38].
In our study, all patients have achieved satisfactory results, and postoperative pain, hip joint function and walking ability have all been greatly improved. This seems to indicate that patients with AO can get a more satisfactory effect after direct anterior total hip replacement, that is, AO is not a contraindication for direct anterior total hip replacement, and especially for patients with pulmonary hypertension, it can reduce their peripheral circulation.
AO was the metabolic syndrome component that was a predictor of exercise performance during the 6-minute walk test[39]. AO had a significant impact on sports performance and physical activity. The blood flow of the calf was significantly reduced, which increased the risk of thrombosis in surgical patients. However, there was no significant statistical difference in the 6wt preoperative baseline data of the two groups in this study. The specific reason is not yet clear. Perhaps the pain of hip and limited movement of lower limbs covered the impact of AO on walking ability. This requires further research. In terms of the 6wt improvement of the two groups, the AO group was significantly lower than the non-AO group, and the two groups of data were statistically significant(p = 0.001). But it cannot be ruled out that the impact of AO on walking ability would appear after pain of hip and limited movement of lower limbs were removed. No patient with thrombosis was found in this study. The specific reason may be the current general use of “Low Molecular Weight Heparin Sodium Injection” in THA. The impact of the reduction of peripheral circulation on the recovery of the soft tissues of the lower extremity wounds was not mentioned in this study due to the long follow-up time.
As far as we know, this is the first study to investigate the clinical effects of AO on the clinical outcomes after THA. The surgical method used in this study was a direct anterior approach, and some additional measures were taken during the operation for patients with AO. This is not seen in other studies, which may be the reason why our results conflict with other studies. The follow-up time of this study is about 1 year, which is relatively short compared with other studies. To understand the long-term effects of AO on TKA surgery, longer follow-up is needed. This study only counted the patient's weight and abdominal circumference before surgery, but did not consider the patient's weight and abdominal circumference changes during the follow-up period. Finally, the sample size of this study was insufficient for 64 patients, and the sample size should be expanded to conduct more in-depth studies to confirm our view.
In conclusion, AO does not increase the complications after THA, nor does it have a significant impact on the function after THA, but it seems to have a negative effect on the improvement of walking ability.