Background: Several studies have shown the effectiveness of Metacognitive Therapy (MCT) in treating different mental disorders. Most of these studies were performed in English speaking countries using the original English version of the manual. Our study aimed to examine the feasibility of the translated MCT manual in a sample of German patients with major depressive disorder.
Methods: 20 outpatients (6 male, 14 female, mean age 42.1y) with major depressive disorder were included. The main outcome was drop-out rate and satisfaction with the treatment; secondary outcomes were changes in metacognitive beliefs assessed with the metacognitive questionnaire 30 (MCQ-30), and symptom reduction measured with the Beck Depression Inventory-2 sum score (BDI-2).
Results: No drop-outs during the treatment and the follow-up phase were observed. Patients and therapists were highly satisfied with MCT treatment. The MCQ-30 significantly declined over the treatment course, paralleled by a significant reduction of the BDI-2 sum scores (from 29 ± 8.6 at T0 to 8.4 ± 9.6 at the end of treatment).The average treatment duration was 10 ± 4 sessions.
Conclusions: Applying the German version of the manual for Metacognitive Therapy proved to be feasible in the treatment of depressed patients in an outpatient setting. The treatment was well tolerated by German patients. Outcome in terms of reduction of depressive symptoms was good. Remarkable is the comparably short treatment duration which should be investigated further in future studies.
Trial registration: German Clinical Trials Register (DRKS): DRKS00023644, 17.11.2020 (retrospectively registered).

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Posted 03 Dec, 2020
On 21 Nov, 2020
On 17 Nov, 2020
On 20 Oct, 2020
On 24 Sep, 2020
Received 08 Sep, 2020
Received 03 Sep, 2020
On 27 Aug, 2020
On 15 Aug, 2020
Invitations sent on 11 Aug, 2020
On 02 Aug, 2020
On 01 Aug, 2020
On 01 Aug, 2020
On 30 Jul, 2020
Posted 03 Dec, 2020
On 21 Nov, 2020
On 17 Nov, 2020
On 20 Oct, 2020
On 24 Sep, 2020
Received 08 Sep, 2020
Received 03 Sep, 2020
On 27 Aug, 2020
On 15 Aug, 2020
Invitations sent on 11 Aug, 2020
On 02 Aug, 2020
On 01 Aug, 2020
On 01 Aug, 2020
On 30 Jul, 2020
Background: Several studies have shown the effectiveness of Metacognitive Therapy (MCT) in treating different mental disorders. Most of these studies were performed in English speaking countries using the original English version of the manual. Our study aimed to examine the feasibility of the translated MCT manual in a sample of German patients with major depressive disorder.
Methods: 20 outpatients (6 male, 14 female, mean age 42.1y) with major depressive disorder were included. The main outcome was drop-out rate and satisfaction with the treatment; secondary outcomes were changes in metacognitive beliefs assessed with the metacognitive questionnaire 30 (MCQ-30), and symptom reduction measured with the Beck Depression Inventory-2 sum score (BDI-2).
Results: No drop-outs during the treatment and the follow-up phase were observed. Patients and therapists were highly satisfied with MCT treatment. The MCQ-30 significantly declined over the treatment course, paralleled by a significant reduction of the BDI-2 sum scores (from 29 ± 8.6 at T0 to 8.4 ± 9.6 at the end of treatment).The average treatment duration was 10 ± 4 sessions.
Conclusions: Applying the German version of the manual for Metacognitive Therapy proved to be feasible in the treatment of depressed patients in an outpatient setting. The treatment was well tolerated by German patients. Outcome in terms of reduction of depressive symptoms was good. Remarkable is the comparably short treatment duration which should be investigated further in future studies.
Trial registration: German Clinical Trials Register (DRKS): DRKS00023644, 17.11.2020 (retrospectively registered).

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