This paper focuses on the vector control scheme of surface-mounted permanent magnet synchronous motorized spindle, to solve the problem of poor speed regulation performance of spindle under high-speed operation conditions, according to the principle of double closed-loop vector control, the characteristics of speed loop and current loop are analyzed, and fuzzy theory is introduced to optimize the traditional speed loop PI controller, furthermore the system parameters are adjusted in real time. Aiming at improving the dynamic response ability of the control system, a first-order linear active disturbance rejection controller is proposed to replace the traditional current loop PI controller, which enhances the anti-interference ability of the system. Experimental results show that the fuzzy PI-LADRC combined control strategy can effectively reduce stator current ripple and torque ripple, and improve the dynamic response speed and anti-interference ability of the system. At last can also improve the output performance of the motorized spindle.