Although a multidisciplinary team (MDT) approach is recommended in advanced heart failure and heart transplantation (HTx), no studies have discussed the impact of the team approach on the clinical outcomes of HTx. In 2014, we established an MDT approach in our HTx program with active involvement of teams for critical care and extracorporeal life support (ECLS) using a real-time online information sharing system. We hypothesized that this MDT approach improved the survival of patients who have undergone HTx. In this study, we enrolled 250 adult patients who underwent HTx between December 2003 and June 2018; they were divided into non-MDT (n = 120; before 2014) and MDT (n = 130; since 2014) groups, with the primary outcome being overall mortality. The mean age of HTx recipients was 51.0 ± 13.7 years, and 77 recipients (30.8%) were female. The MDT group had more high-risk patients in terms of age of donors, diabetes, dialysis, ECLS, and waiting time. Various multivariable analytic methods, including inverse-probability-of-treatment-weighting analysis, revealed that the MDT approach was an independent predictor of overall survival. Therefore, collaboration of an HF team, a critical care team, and an ECLS team may improve survival after HTx.

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No competing interests reported.
This is a list of supplementary files associated with this preprint. Click to download.
Supplementary Figure Legends
Supplementary Figure S1
Supplementary Figure S2
Supplementary Figure S3
Supplementary Table S1
Supplementary Table S2
Supplementary Table S3
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Posted 25 May, 2021
Posted 25 May, 2021
Although a multidisciplinary team (MDT) approach is recommended in advanced heart failure and heart transplantation (HTx), no studies have discussed the impact of the team approach on the clinical outcomes of HTx. In 2014, we established an MDT approach in our HTx program with active involvement of teams for critical care and extracorporeal life support (ECLS) using a real-time online information sharing system. We hypothesized that this MDT approach improved the survival of patients who have undergone HTx. In this study, we enrolled 250 adult patients who underwent HTx between December 2003 and June 2018; they were divided into non-MDT (n = 120; before 2014) and MDT (n = 130; since 2014) groups, with the primary outcome being overall mortality. The mean age of HTx recipients was 51.0 ± 13.7 years, and 77 recipients (30.8%) were female. The MDT group had more high-risk patients in terms of age of donors, diabetes, dialysis, ECLS, and waiting time. Various multivariable analytic methods, including inverse-probability-of-treatment-weighting analysis, revealed that the MDT approach was an independent predictor of overall survival. Therefore, collaboration of an HF team, a critical care team, and an ECLS team may improve survival after HTx.

Figure 1

Figure 2

Figure 3

Figure 4
No competing interests reported.
This is a list of supplementary files associated with this preprint. Click to download.
Supplementary Figure Legends
Supplementary Figure S1
Supplementary Figure S2
Supplementary Figure S3
Supplementary Table S1
Supplementary Table S2
Supplementary Table S3
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