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Case report
Tige Cycline Successfully Treats One Case of Relapsed Leukemia-drug-resistant Double Sepsis
Fei Xiao Fan
Department of Pharmacy，West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China
Corresponding Author
ORCiD: https://orcid.org/0000-0003-0178-3863
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
Nowadays, tigecycline is often used in combination with other antibiotics. To the best of our knowledge, this was the first documented use tigecycline alone for drug-resistant double sepsis in a patient suffering from leukemia.. The aim of this study is to reduce unnecessary drug combinations associated with tigecycline and use antibiotics reasonably.
Methods
The patient was a relapsed patient with advanced acute leukemia, with severe perianal infection and neutrophil deficiency. At the same time, blood culture suggested Acinetobacter luffi (Imipenem resistance) and Enterococcus faecium (vancomycin resistance). The doctor has no other choice according to drug susceptibility results. Tigecycline is used alone, and conventional doses are used .
Results
the patient's temperature gradually became normal, blood pressure was stable, blood in the stool stopped, perianal swelling subsided, pain was reduced, and infection improved.
Conclusion
generally speaking, tigecycline is a bacteriostatic agent; doctors are used to a combination of Tigecycline and other antibiotics in fighting infections.In this case, the patient's immunity is low.Tigecycline is used alone, and conventional doses are used to achieve the effect of curing double sepsis experience.This helps in the rational use of antibiotics.
Keywords
tigecycline, vancomycin resistance, Enterococcus faecium, Acinetobacterluffi
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This is a preprint. It has not completed peer review.
Case report
Tige Cycline Successfully Treats One Case of Relapsed Leukemia-drug-resistant Double Sepsis
Fei Xiao Fan
Department of Pharmacy，West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China
Corresponding Author
ORCiD: https://orcid.org/0000-0003-0178-3863
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 17 Aug, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
Nowadays, tigecycline is often used in combination with other antibiotics. To the best of our knowledge, this was the first documented use tigecycline alone for drug-resistant double sepsis in a patient suffering from leukemia.. The aim of this study is to reduce unnecessary drug combinations associated with tigecycline and use antibiotics reasonably.
Methods
The patient was a relapsed patient with advanced acute leukemia, with severe perianal infection and neutrophil deficiency. At the same time, blood culture suggested Acinetobacter luffi (Imipenem resistance) and Enterococcus faecium (vancomycin resistance). The doctor has no other choice according to drug susceptibility results. Tigecycline is used alone, and conventional doses are used .
Results
the patient's temperature gradually became normal, blood pressure was stable, blood in the stool stopped, perianal swelling subsided, pain was reduced, and infection improved.
Conclusion
generally speaking, tigecycline is a bacteriostatic agent; doctors are used to a combination of Tigecycline and other antibiotics in fighting infections.In this case, the patient's immunity is low.Tigecycline is used alone, and conventional doses are used to achieve the effect of curing double sepsis experience.This helps in the rational use of antibiotics.