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Research article
Liangmei Chen
Second Hospital of Jilin University
Corresponding Author
ORCiD: https://orcid.org/0000-0001-9350-9081
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The association between handgrip strength (HGS) and pulmonary function is still controversial, and this relationship has not yet been established among the healthy Chinese Han population.
Methods: Data from 1519 healthy Han community dwellers in Beijing were analysed. Subjects were divided into two groups by age: the younger group (<60 years) and the elderly group (≥60 years). Bivariate correlation tests were run between parameters, and variables with a correlation coefficient ǀrǀ≥0.30 and p<0.01 were considered to be significantly correlated. Multiple linear regression analysis was used to adjust covariates in the relationship between HGS and pulmonary function.
Results: The study included 623 males and 896 females. The values of HGS were greater in males than in females (40.2 kg vs 25.0 kg, p<0.01) and greater in the younger group than in the elderly group (33.3 kg vs 27.6 kg, p<0.01). HGS and parameters of pulmonary function were highly negatively correlated with age, especially forced expiratory volume in 1 second (r=-0.55, p<0.01), forced expiratory volume in 2 second (r=-0.53, p<0.01) and forced vital capacity (FVC) (r=-0.50, p<0.01). Parameters of pulmonary function were positively associated with HGS, especially the maximum value of vital capacity (VC max) (r=-0.72, p<0.01), forced expiratory volume in 3 second (FEV 3) (r=0.70, p<0.01) and FVC (r=0.69, p<0.01). Therefore, we selected VC max, FEV 3 and FVC as three representative parameters to analyse the relationship between HGS and pulmonary function. In the relationship between HGS and pulmonary function, in addition to gender and age, there were other covariates: height, pulse pressure and systolic blood pressure. After adjusting covariates in the multiple linear regression analysis, the standardized coefficients of HGS on VC max were 0.254 in males and 0.175 in females, and the standardized coefficients of HGS on FVC were 0.225 in males and 0.182 in females.
Conclusions: Pulmonary function and HGS were both declined with age. HGS was an independent factor that affected pulmonary function, apart from age. Training in HGS may help to improve pulmonary function in healthy people.
Keywords
Handgrip strength, Pulmonary function, Age, FVC, Chinese
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View the published article at BMC Pulmonary Medicine.
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Editorial decision: Minor revision
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Editorial decision: Minor revision
On 29 Mar, 2020
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On 15 Mar, 2020
Editor invited
On 14 Mar, 2020
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On 09 Mar, 2020
No comments provided
Editorial decision: Minor revision
On 05 Mar, 2020
Reviewers invited
Invitations sent on 20 Jan, 2020
Editor assigned
On 17 Jan, 2020
Submission checks complete
On 16 Jan, 2020
Editor invited
On 16 Jan, 2020
Version 1
Posted 19 Sep, 2019
No comments provided
Editorial decision: Major revision
On 02 Jan, 2020
Review #1 received
Received 29 Dec, 2019
Review #2 received
Received 26 Dec, 2019
Reviewer #2 agreed
On 16 Dec, 2019
Reviewers invited
Invitations sent on 11 Dec, 2019
Reviewer #1 agreed
On 11 Dec, 2019
Submission checks complete
On 16 Sep, 2019
Editor assigned
On 12 Sep, 2019
Editor invited
On 11 Sep, 2019
First submitted
On 10 Sep, 2019
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Subject Areas
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A new preprint design is coming!
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See the published version of this preprint at BMC Pulmonary Medicine.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Liangmei Chen
Second Hospital of Jilin University
Corresponding Author
ORCiD: https://orcid.org/0000-0001-9350-9081
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Pulmonary Medicine.
No community comments so far
Editorial decision: Minor revision
On 08 Apr, 2020
Editor assigned
On 01 Apr, 2020
Submission checks complete
On 31 Mar, 2020
Editor invited
On 31 Mar, 2020
No comments provided
Editorial decision: Minor revision
On 29 Mar, 2020
Editor assigned
On 15 Mar, 2020
Editor invited
On 14 Mar, 2020
Submission checks complete
On 09 Mar, 2020
No comments provided
Editorial decision: Minor revision
On 05 Mar, 2020
Reviewers invited
Invitations sent on 20 Jan, 2020
Editor assigned
On 17 Jan, 2020
Submission checks complete
On 16 Jan, 2020
Editor invited
On 16 Jan, 2020
Version 1
Posted 19 Sep, 2019
No comments provided
Editorial decision: Major revision
On 02 Jan, 2020
Review #1 received
Received 29 Dec, 2019
Review #2 received
Received 26 Dec, 2019
Reviewer #2 agreed
On 16 Dec, 2019
Reviewers invited
Invitations sent on 11 Dec, 2019
Reviewer #1 agreed
On 11 Dec, 2019
Submission checks complete
On 16 Sep, 2019
Editor assigned
On 12 Sep, 2019
Editor invited
On 11 Sep, 2019
First submitted
On 10 Sep, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Pulmonology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Pulmonary Medicine.
Background: The association between handgrip strength (HGS) and pulmonary function is still controversial, and this relationship has not yet been established among the healthy Chinese Han population.
Methods: Data from 1519 healthy Han community dwellers in Beijing were analysed. Subjects were divided into two groups by age: the younger group (<60 years) and the elderly group (≥60 years). Bivariate correlation tests were run between parameters, and variables with a correlation coefficient ǀrǀ≥0.30 and p<0.01 were considered to be significantly correlated. Multiple linear regression analysis was used to adjust covariates in the relationship between HGS and pulmonary function.
Results: The study included 623 males and 896 females. The values of HGS were greater in males than in females (40.2 kg vs 25.0 kg, p<0.01) and greater in the younger group than in the elderly group (33.3 kg vs 27.6 kg, p<0.01). HGS and parameters of pulmonary function were highly negatively correlated with age, especially forced expiratory volume in 1 second (r=-0.55, p<0.01), forced expiratory volume in 2 second (r=-0.53, p<0.01) and forced vital capacity (FVC) (r=-0.50, p<0.01). Parameters of pulmonary function were positively associated with HGS, especially the maximum value of vital capacity (VC max) (r=-0.72, p<0.01), forced expiratory volume in 3 second (FEV 3) (r=0.70, p<0.01) and FVC (r=0.69, p<0.01). Therefore, we selected VC max, FEV 3 and FVC as three representative parameters to analyse the relationship between HGS and pulmonary function. In the relationship between HGS and pulmonary function, in addition to gender and age, there were other covariates: height, pulse pressure and systolic blood pressure. After adjusting covariates in the multiple linear regression analysis, the standardized coefficients of HGS on VC max were 0.254 in males and 0.175 in females, and the standardized coefficients of HGS on FVC were 0.225 in males and 0.182 in females.
Conclusions: Pulmonary function and HGS were both declined with age. HGS was an independent factor that affected pulmonary function, apart from age. Training in HGS may help to improve pulmonary function in healthy people.
Figure 1
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