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Research note
Yohana Silas Mtali
Muhimbili University of Health and Allied Sciences School of Medicine
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3052-8434
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Objectives This study aimed at determining the changes of hematological parameters in newborns of mothers with HDP compared to normotensive mothers.Results This was a hospital-based comparative cross-sectional study conducted from December 2017 to May 2018. The study groups consisted of 70 normotensives and 73 hypertensive pregnant women as a comparison and index group respectively. The male to female ratio for the newborns was 1:1. Newborns of the hypertensive mothers had a lower birth weight, lower APGAR score and had a lower median gestation age at the time of birth compared to the newborns of normotensive mothers (P < 0001). White blood cell and differential counts were lower in cord blood of the newborns of HDP group than in the normotensive group (P≤0.001). Approximately 50% of newborns of hypertensive mothers had thrombocytopenia. Furthermore, hypertensive disorders of pregnancy were found to independently predict neutropenia [OR=6 (2.1 – 19.4), p<0.05] and thrombocytopenia [OR=4.3(1.7 – 11.1), p<0.001] in the newborns.
Keywords
Hematological Profile, Pregnancy, Newborns, Cord blood, Hypertensive disorders, Preeclampsia.
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research note
Yohana Silas Mtali
Muhimbili University of Health and Allied Sciences School of Medicine
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3052-8434
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 24 Sep, 2019
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Maternal & Fetal Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Objectives This study aimed at determining the changes of hematological parameters in newborns of mothers with HDP compared to normotensive mothers.Results This was a hospital-based comparative cross-sectional study conducted from December 2017 to May 2018. The study groups consisted of 70 normotensives and 73 hypertensive pregnant women as a comparison and index group respectively. The male to female ratio for the newborns was 1:1. Newborns of the hypertensive mothers had a lower birth weight, lower APGAR score and had a lower median gestation age at the time of birth compared to the newborns of normotensive mothers (P < 0001). White blood cell and differential counts were lower in cord blood of the newborns of HDP group than in the normotensive group (P≤0.001). Approximately 50% of newborns of hypertensive mothers had thrombocytopenia. Furthermore, hypertensive disorders of pregnancy were found to independently predict neutropenia [OR=6 (2.1 – 19.4), p<0.05] and thrombocytopenia [OR=4.3(1.7 – 11.1), p<0.001] in the newborns.
This is a list of supplementary files associated with this preprint. Click to download.
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