Ethics approval and consent to participate: The protocol and informed consent were reviewed and approved by the institutional review board at Fuwai Hospital of Chinese Academy of Medical Sciences and Beijing Hypertension League Institute.
Consent for publication: Not applicable.
Availability of data and materials: The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.
Funding: The main PURE study and its components are funded by the Population Health Research Institute, the Canadian Institutes of Health Research, Heart and Stroke Foundation of Ontario, and through unrestricted grants from several pharmaceutical companies. Besides funding from global PURE, this work was also sponsored by CAMS Innovation Fund for Medical Sciences (CIFMS): 2016-I2M-2-004, Construction of Basic Information Technology Support System and Platform for National Prevention and Treatment of Cardiovascular Diseases. This work was also supported by funding from the National Science Foundation of China (81973324), Hunan Young Talent grant (2020RC3063), Hunan Science Foundation (2020JJ5858) and the Wisdom Accumulation and Talent Cultivation Project of the Third XiangYa hosipital of Central South University (YX202002).
Authors' contributions: Wei Li and Lu Yin designed the study. Data analysis was completed by Ying Li. The manuscript was drafted by Ying Li and Lu Yin. The manuscript was reviewed and edited by Andrew Mente, Sumathy Rangarajan, Yuebo Wang, Xiaoyun Liu, Congke Zhao, Haibin Ma, Yi Sun, Peng Zhang, Li Zhang, Xiaolin Zhang and Wei Li.
Acknowledgements: Besides co-authors listed in this study, we would like to thank those who supported our study and what they did with our sincere gratitude, especially for site coordinators, physicians, nurses, questionnaire interviewers, and laboratory personnel in all participating centers and communities, included China Coordination Center Beijing Office: Lisheng Liu, Wei Li, Hongye Zhang, Hui Chen, Jian Bo, Jian Li, Kean Wang, Xiaoru Cheng, Xixin Hou, Xingyu Wang, Xiulin Bai, Xu Liu, Xuan Jia, Yi Sun, Yang Wang, Lu Yin; Jishuitan Hospital, Beijing: Di Chen,Dong Li, Hui Jin, Jiwen Tian; Center for Disease Control & Prevention, Shunyi District, Beijing: Yindong Li, Kai You, Changqing Li, Songjian Zhang,Wenlong Cheng,Hongye Zhang; Hospital of Traditional Chinese Medicine, Shijingshan District, Beijing: Honghong Li,Qiang Zhou, Xu Xu,Yanhong Sun, Jinling Di, Jianquan Wu, Mei Wang; Bayannaoer Center for Disease Control & Prevention, Inner Mongolia: Minzhi Cao,Shiying Zhang, Aiying Han; Center for Disease Control & Prevention, Wujin District, Changzhou City, Jiangsu Province: Jianxin Zhou, Yihong Zhou, Deren Qiang, Jianfang Wu,Zhaowei Li,Jing Qin,Suyi Shi,Zhihua Fan,Alin Qian,Lingyun Pan,Minrui Xu,Yibing Cui; Jiangsu provincial hospital:Jun Li,Yongzhen Mo, Center for Disease Control & Prevention, Jiangsu Province: Quanyong Xiang;Ye Cao, Jiangxinzhou Community Health Service Center, Nanjing City, Jiangsu Province: Zhenzhen Qian, Zhengrong Liu; Health Service Center, Nanhu District, Nanjing City, Jiangsu Province: Xiangrong He;Changlin Dong,Ming Wan; Xiaohang Hospital, Nanjing City, Jiangsu Province: Jinhua Tang; Center for Disease Control & Prevention, Nanchang County, Jiangxi Province: Rensheng Lei, Lihua Hu,Shuwei Xiong; Qingshanhu Community Health Service Center, Nanchang City, Jiangxi Province: Ning Li, Xincheng Tang,Dan Zou,Qilu Gan,Shuli Ye; Shenyang 242 Hospital, Liaoning Province: Yu Liu; Health Center, Daxing District, Shenyang City, Liaoning Province: Minfan Fu, Qiuyuan Wang; Red Cross Hospital, Shenyang City, Liaoning Province: Baoxia Guo, Huilian Feng, Xiaojie Xing; Center for Disease Control & Prevention, Xining City, Qinghai Province: Yuqing Yang, Wenqiang Xu, Haibin Ma,Yali Wang; Huizu Hospital, Xining City, Qinghai Province: Youzhu Yang, Xiaolan Ma,Yan Hai,Zhe Xie,Yuanting Ma; Huaxi Hospital, Chengdu City, Sichuan Province: Xiaoyang Liao, Qian Zhao,Chuan Zou; Jianshe Road Community Health Service Center, Chengdu City, Sichuan Province: Guofan Xu,Jiankang Liu; Health Center, Dayicaichang Town, Sichuan Province: Xiaolin Zhang,Wenqing Deng; Cardiovascular Disease Research Institute, Shandong Province: Fanghong Lu, Hua Zhang, Shangwen Sun, Yingxin Zhao, Zhendong Liu,Falian Sun; Jingle County Hospital, Shanxi Province: Yinsheng Wu, Guoqin Liu; Balingqiao Community Health Service Station, Xinghualing District, Taiyuan City, Shanxi Province: Yan Hou, Junying Wang,Hua Wei; Electronic Science and Technology University Hospital, Xi'an City, Shaanxi Province: Xiaoxia Li, Yahong Zhi,Tianlu Liu; Guanshan Town Hospital, Yanliang District, Xi'an City, Shaanxi Province: Peng Zhang; Center for Disease Control & Prevention, Hetian City, Xinjiang Province: Ayoufu Aideer Aili, Mitiwula, Reshalaiti, Hui Wang; Health Center, Damenglong Town, Xishuangbanna Prefecture, Yunnan Province: Qiyun Wang, Jinkui Yang,Kehua Li; Center for Disease Control & Prevention, Mengla County, Xishuangbanna Prefecture, Yunnan Province: Huaxing Liu, Chunmei Liu; Center for Disease Control & Prevention, Yunnan Province: Yize Xiao.