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Research article
Broad Spectrum Polyphenol Supplementation from Tart Cherry Extract on Markers of Recovery from Intense Resistance Exercise
David R. Hooper
Brightwood College
Corresponding Author
ORCiD: https://orcid.org/0000-0002-6610-6583
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Tart cherry supplementation has been shown to enhance recovery from strenuous exercise due to its antioxidant properties. The majority of these studies used tart cherry juice, with a significant calorie content. The primary purpose of this study was to assess whether powdered tart cherry extract with minimal calorie content reduces oxidative stress and enhances recovery following intense resistance exercise.
Methods: Thirteen men (mean age: 26.2±5.3 years; height: 184.3±8.2 cm; weight: 92.9±15.6 kg) performed a demanding resistance exercise protocol consisting of 6 sets of 10 repetitions of barbell back squat with 80% 1RM. The protocol was performed once following 7 days of 500 mg of tart cherry extract and once following placebo. Serum protein carbonyl (PC) content, creatine kinase activity (CK) and creatine kinase myocardial band content (CK-MB) were used to assess oxidative stress, skeletal and cardiac muscle damage respectively. Muscle soreness was assessed by visual analog scale. Physical performance was measured by countermovement jump power and handgrip dynamometer strength.
Results: There was a significant increase in PC in the placebo (PL) condition when compared to the Tart Cherry (TC) condition at IP (PL: 0.4±0.3 vs. TC: -0.4±0.2 nmol∙mg-1; p<0.001), 1 hr (PL: 0.3±0.3 vs. TC: -0.7±0.3 nmol∙mg-1; p<0.001) and 24 hr (PL: 0.1±0.4 vs. TC: -0.3±0.5 nmol∙mg-1; p=0.010). There was a significant increase in CK activity in PL when compared to the TC at IP (PL: 491.1±280 vs. TC: 296.3±178 U∙L-1; p=0.008) and 3 hr (PL: -87±123 vs. TC: 43.1±105.3 U∙L-1; p=0.006). There was a significant (p=0.003) increase in CKMB concentration in PL when compared to the TC (PL: 21.6±12.4 vs. TC: -0.3±11.8 ng∙ml-1; p=0.006) at 1 hr post. There was a significant increase in handgrip strength in TC when compared to PL (PL: -2±5.1 vs. TC: 1.7±3 kg; p=0.017) at 24 hours post.
Conclusions: This study demonstrated that tart cherry extract reduced oxidative stress and markers of muscle and cardiac damage following intense resistance exercise. This occurred along with a prevention of the decrease in strength seen following the intense exercise protocol. These benefits were seen with minimal energy intake.
Keywords
Tart cherry, antioxidants, polyphenols, recovery, muscle damage, cardiac damage
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On 28 Aug, 2020
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This preprint is under consideration at Journal of the International Society of Sports Nutrition. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Broad Spectrum Polyphenol Supplementation from Tart Cherry Extract on Markers of Recovery from Intense Resistance Exercise
David R. Hooper
Brightwood College
Corresponding Author
ORCiD: https://orcid.org/0000-0002-6610-6583
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 2
Posted 04 Dec, 2020
No community comments so far
Review #3 received
Received 12 Jan, 2021
Review #2 received
Received 07 Jan, 2021
Reviewer #3 agreed
On 06 Dec, 2020
Reviewer #2 agreed
On 06 Dec, 2020
Reviewer #1 agreed
On 05 Dec, 2020
Reviewers invited
Invitations sent on 03 Dec, 2020
Editor assigned
On 22 Nov, 2020
Submission checks complete
On 22 Nov, 2020
Editor invited
On 22 Nov, 2020
No comments provided
Editorial decision: Revise before peer review
On 28 Aug, 2020
First submitted
On 09 Aug, 2020
Editor assigned
On 09 Aug, 2020
Submission checks complete
On 08 Aug, 2020
Editor invited
On 08 Aug, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Sports Medicine and Kinesiology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Tart cherry supplementation has been shown to enhance recovery from strenuous exercise due to its antioxidant properties. The majority of these studies used tart cherry juice, with a significant calorie content. The primary purpose of this study was to assess whether powdered tart cherry extract with minimal calorie content reduces oxidative stress and enhances recovery following intense resistance exercise.
Methods: Thirteen men (mean age: 26.2±5.3 years; height: 184.3±8.2 cm; weight: 92.9±15.6 kg) performed a demanding resistance exercise protocol consisting of 6 sets of 10 repetitions of barbell back squat with 80% 1RM. The protocol was performed once following 7 days of 500 mg of tart cherry extract and once following placebo. Serum protein carbonyl (PC) content, creatine kinase activity (CK) and creatine kinase myocardial band content (CK-MB) were used to assess oxidative stress, skeletal and cardiac muscle damage respectively. Muscle soreness was assessed by visual analog scale. Physical performance was measured by countermovement jump power and handgrip dynamometer strength.
Results: There was a significant increase in PC in the placebo (PL) condition when compared to the Tart Cherry (TC) condition at IP (PL: 0.4±0.3 vs. TC: -0.4±0.2 nmol∙mg-1; p<0.001), 1 hr (PL: 0.3±0.3 vs. TC: -0.7±0.3 nmol∙mg-1; p<0.001) and 24 hr (PL: 0.1±0.4 vs. TC: -0.3±0.5 nmol∙mg-1; p=0.010). There was a significant increase in CK activity in PL when compared to the TC at IP (PL: 491.1±280 vs. TC: 296.3±178 U∙L-1; p=0.008) and 3 hr (PL: -87±123 vs. TC: 43.1±105.3 U∙L-1; p=0.006). There was a significant (p=0.003) increase in CKMB concentration in PL when compared to the TC (PL: 21.6±12.4 vs. TC: -0.3±11.8 ng∙ml-1; p=0.006) at 1 hr post. There was a significant increase in handgrip strength in TC when compared to PL (PL: -2±5.1 vs. TC: 1.7±3 kg; p=0.017) at 24 hours post.
Conclusions: This study demonstrated that tart cherry extract reduced oxidative stress and markers of muscle and cardiac damage following intense resistance exercise. This occurred along with a prevention of the decrease in strength seen following the intense exercise protocol. These benefits were seen with minimal energy intake.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5