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Research Article
Apoorva Karsolia
University of Houston
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Knowledge of eye position in the brain is critical for localization of objects in space. To investigate the accuracy and precision of eye position feedback in an unreferenced environment, subjects with normal ocular alignment attempted to localize briefly presented targets during monocular and dichoptic viewing. In the task, subjects’ used a computer mouse to position a response disk at the remembered location of the target. Under dichoptic viewing (with red (right eye) - green (left eye) glasses), target and response disks were presented to the same or alternate eyes, leading to four conditions [green target – green response cue (LL), green-red (LR), red-green (RL), and red-red (RR)]. Time interval between target and response disks was varied and localization errors were the difference between the estimated and real positions of the target disk. Overall, the precision of spatial localization (variance across trials) became progressively worse with time. Under dichoptic viewing, localization errors were significantly greater for alternate-eye trials as compared to same-eye trials and were correlated to the average phoria of each subject. We suggest that during these tasks, subjects are unable to compensate for their phoria, implying that oculomotor proprioception may not provide the required feedback of eye position.
Keywords
Localization, dichoptic viewing, eye position signals, psychophysics, oculomotor proprioception, normal ocular alignment
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No competing interests reported.
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CURRENT STATUS: Under Review
Version 1
Posted 04 Jun, 2021
No community comments so far
Editorial decision: Major revision
On 03 Aug, 2021
Reviews received
Received 28 Jul, 2021
Reviewers agreed
On 09 Jul, 2021
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Editor assigned
On 09 Jul, 2021
Editor invited
On 02 Jun, 2021
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On 02 Jun, 2021
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Subject Areas
Infectious Diseases
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A new preprint design is coming!
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This preprint is under consideration at Scientific Reports. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Apoorva Karsolia
University of Houston
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 04 Jun, 2021
No community comments so far
Editorial decision: Major revision
On 03 Aug, 2021
Reviews received
Received 28 Jul, 2021
Reviewers agreed
On 09 Jul, 2021
Reviewers invited
Invitations sent on 09 Jul, 2021
Editor assigned
On 09 Jul, 2021
Editor invited
On 02 Jun, 2021
Submission checks complete
On 02 Jun, 2021
First submitted
On 01 Jun, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Infectious Diseases
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Knowledge of eye position in the brain is critical for localization of objects in space. To investigate the accuracy and precision of eye position feedback in an unreferenced environment, subjects with normal ocular alignment attempted to localize briefly presented targets during monocular and dichoptic viewing. In the task, subjects’ used a computer mouse to position a response disk at the remembered location of the target. Under dichoptic viewing (with red (right eye) - green (left eye) glasses), target and response disks were presented to the same or alternate eyes, leading to four conditions [green target – green response cue (LL), green-red (LR), red-green (RL), and red-red (RR)]. Time interval between target and response disks was varied and localization errors were the difference between the estimated and real positions of the target disk. Overall, the precision of spatial localization (variance across trials) became progressively worse with time. Under dichoptic viewing, localization errors were significantly greater for alternate-eye trials as compared to same-eye trials and were correlated to the average phoria of each subject. We suggest that during these tasks, subjects are unable to compensate for their phoria, implying that oculomotor proprioception may not provide the required feedback of eye position.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Figure 9
Figure 10
Figure 11
No competing interests reported.
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