This research provides a novel intelligent control structure for 4D nonlinear hyperchaotic systems. This is a hybrid design containing a new interval type-2 fuzzy fourfold function-link brain emotional controller and a smooth robust controller. It comprises a fuzzy inference system and three subnetworks. The subnetworks are a new fourfold function-link network, a type-2 fuzzy amygdala network and a type-2 fuzzy prefrontal cortex network that decrease the synchronization errors efficiently, follow the reference signal well and achieve good performance. Two Lyapunov stability functions are utilized to get the adaptive laws, and they are applied to online tune the parameters of the system. The proposed design is used to synchronize two 4D nonlinear hyperchaotic systems and the simulation results are given to demonstrate its superiority and effectiveness.