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Research article
Chiao-Zhu Li
Tri-Service General Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0001-8373-2423
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This work is licensed under a CC BY 4.0 License. Read Full License
Background Studies show that vertebral fractures could predict the risk of hip fractures. We aimed to evaluate the potential benefits of whether the timing of vertebroplasty (VP) for vertebral fracture associated with the risk of hip fracture for hip replacement.
Methods We identified 142,782 patients from the Taiwan National Health Insurance Database with thoracolumbar vertebral fracture (TLCF) (ICD-9-CM: 805.2-805.9) who were followed up from 2000 to 2013. These patients were divided into those who underwent VP (VP group) (ICD-9-CM: 78.49) within 3 months and those who did not (non-VP group). After adjusting for the confounding factors, the Cox proportional hazards analysis was used to estimate the effect of early VP on reducing the risk of hip fracture.
Results In the 14-year follow-up, the cumulative incidence rate of hip replacement in the VP group was lower than that in the non-VP group (0.362% and 0.533%, respectively, long-rank p<0.001). There was a significant difference between the two groups since the first-year follow-up.
Conclusion Our study showed that early VP performed to avoid progression of the kyphotic changes following TLCF may reduce the risk of hip fracture. These results, obtained from retrospective data, indicate that a prospective study is warranted.
Keywords
Vertebroplasty, compression fracture, hip fracture, pelvic incidence, sarcopenia, fall
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A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research article
Chiao-Zhu Li
Tri-Service General Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0001-8373-2423
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
View the published article at Medicine.
Version 1
Posted 11 Oct, 2019
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedic Surgery
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Medicine.
Background Studies show that vertebral fractures could predict the risk of hip fractures. We aimed to evaluate the potential benefits of whether the timing of vertebroplasty (VP) for vertebral fracture associated with the risk of hip fracture for hip replacement.
Methods We identified 142,782 patients from the Taiwan National Health Insurance Database with thoracolumbar vertebral fracture (TLCF) (ICD-9-CM: 805.2-805.9) who were followed up from 2000 to 2013. These patients were divided into those who underwent VP (VP group) (ICD-9-CM: 78.49) within 3 months and those who did not (non-VP group). After adjusting for the confounding factors, the Cox proportional hazards analysis was used to estimate the effect of early VP on reducing the risk of hip fracture.
Results In the 14-year follow-up, the cumulative incidence rate of hip replacement in the VP group was lower than that in the non-VP group (0.362% and 0.533%, respectively, long-rank p<0.001). There was a significant difference between the two groups since the first-year follow-up.
Conclusion Our study showed that early VP performed to avoid progression of the kyphotic changes following TLCF may reduce the risk of hip fracture. These results, obtained from retrospective data, indicate that a prospective study is warranted.
Figure 1
Figure 2
Figure 3
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