1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (5th ed.). 2013: Diagnostic and statistical manual of mental disorders (5th ed.).
2. Keller, MB. The long-term clinical course of generalized anxiety disorder. J Clin Psychiatry. 2002; 63 Suppl 8:11-6.
3. Price, M, AC Legrand, ZMF BrierL Hébert-Dufresne.The symptoms at the center: Examining the comorbidity of posttraumatic stress disorder, generalized anxiety disorder, and depression with network analysis. J Psychiatr Res. 2019; 109:52-58.
4. Ruscio, AM, LS Hallion, CCW Lim, S Aguilar-Gaxiola, A Al-Hamzawi, J Alonso, et al.Cross-sectional Comparison of the Epidemiology of DSM-5 Generalized Anxiety Disorder Across the Globe. JAMA Psychiatry. 2017; 74:465-475.
5. Revicki, DA, K Travers, KW Wyrwich, H Svedsäter, J Locklear, MS Mattera, et al.Humanistic and economic burden of generalized anxiety disorder in North America and Europe. J Affect Disord. 2012; 140:103-12.
6. Porensky, EK, MA Dew, JF Karp, E Skidmore, BL Rollman, MK Shear, et al.The burden of late-life generalized anxiety disorder: effects on disability, health-related quality of life, and healthcare utilization. Am J Geriatr Psychiatry. 2009; 17:473-82.
7. Mantella, RC, MA Butters, MA Dew, BH Mulsant, AE Begley, B Tracey, et al.Cognitive impairment in late-life generalized anxiety disorder. Am J Geriatr Psychiatry. 2007; 15:673-9.
8. Gilmour, H.Threshold and subthreshold Generalized Anxiety Disorder (GAD) and suicide ideation. Health Rep. 2016; 27:13-21.
9. Chatterjee, SS, CM BarikarA Mukherjee.Impact of COVID-19 pandemic on pre-existing mental health problems. Asian J Psychiatr. 2020; 51:102071.
10. Yao, H, JH, Chen YF Xu.Patients with mental health disorders in the COVID-19 epidemic. Lancet Psychiatry. 2020; 7:e21.
11. Chen, TR, HC Huang, JH Hsu, WC OuyangKC Lin.Pharmacological and psychological interventions for generalized anxiety disorder in adults: A network meta-analysis. J Psychiatr Res. 2019; 118:73-83.
12. Reinhold, JA, LA Mandos, K RickelsFW Lohoff.Pharmacological treatment of generalized anxiety disorder. Expert Opin Pharmacother. 2011; 12:2457-67.
13. BaldwinS D.Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology. Journal of Psychopharmacology. 2005; 19:567-596.
14. Gomez, AF, AL BarthelSG Hofmann.Comparing the efficacy of benzodiazepines and serotonergic anti-depressants for adults with generalized anxiety disorder: a meta-analytic review. Expert Opin Pharmacother. 2018; 19:883-894.
15. MohlmanJan.A community based survey of older adults' preferences for treatment of anxiety. Psychology & Aging. 2012; 27:1182.
16. Hunot, V, R Churchill, M Silva de LimaV Teixeira.Psychological therapies for generalised anxiety disorder. Cochrane Database Syst Rev. 2007; 2007:Cd001848.
17. Yovel, I.Acceptance and commitment therapy and the new generation of cognitive behavioral treatments. Isr J Psychiatry Relat Sci. 2009; 46:304-9.
18. Hayes, SC.Acceptance and commitment therapy, relational frame theory, and the third wave of behavioral and cognitive therapies. Behavior Therapy. 2005; 35:639-665.
19. Luoma, JB, SC HayesRD Walser.Learning ACT: An acceptance and commitment therapy skills-training manual for therapists. Psychological Record. 2010; 60:549-552.
20. Hayes, SC, KD Strosahl KG Wilson.Acceptance and commitment therapy: An experiential approach to behavior change. Encyclopedia of Psychotherapy. 1999; 9:1–8.
21. Ruiz, FJ, A Peña-Vargas, ES Ramírez, JC Suárez-Falcón, MB García-Martín, DM García-Beltrán, et al.Efficacy of a two-session repetitive negative thinking-focused acceptance and commitment therapy (ACT) protocol for depression and generalized anxiety disorder: A randomized waitlist control trial. Psychotherapy (Chic). 2020; 57:444-456.
22. Wetherell, JL, N Afari, CR Ayers, JA Stoddard, J Ruberg, JT Sorrell, et al.Acceptance and Commitment Therapy for generalized anxiety disorder in older adults: a preliminary report. Behav Ther. 2011; 42:127-34.
23. Andrade, H L., Alonso, J., Mneimneh, Z., et al.Barriers to mental health treatment: results from the WHO World Mental Health surveys. PSYCHOLOGICAL MEDICINE -LONDON. 2014.
24. Andersson, GN Titov.Advantages and limitations of Internet-based interventions for common mental disorders. World Psychiatry. 2014; 13:4-11.
25. Wosik, J, M Fudim, B Cameron, ZF Gellad, A Cho, D Phinney, et al.Telehealth transformation: COVID-19 and the rise of virtual care. J Am Med Inform Assoc. 2020; 27:957-962.
26. Bitar, HS Alismail.The role of eHealth, telehealth, and telemedicine for chronic disease patients during COVID-19 pandemic: A rapid systematic review. Digit Health. 2021; 7:20552076211009396.
27. Tse, J, D LaStella, E Chow, E Kingman, S Pearlman, L Valeri, et al.Telehealth Acceptability and Feasibility Among People Served in a Community Behavioral Health System During the COVID-19 Pandemic. Psychiatr Serv. 2021:appips202000623.
28. Hemmings, NR, JM Kawadler, R Whatmough, S Ponzo, A Rossi, D Morelli, et al.Development and Feasibility of a Digital Acceptance and Commitment Therapy-Based Intervention for Generalized Anxiety Disorder: Pilot Acceptability Study. JMIR Form Res. 2021; 5:e21737.
29. Moher, D, L Shamseer, M Clarke, D Ghersi, A Liberati, M Petticrew, et al.Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. 2015; 4:1.
30. Higgins, JP, DG Altman, PC Gøtzsche, P Jüni, D Moher, AD Oxman, et al.The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. Bmj. 2011; 343:d5928.
31. Guyatt, GH, AD Oxman, GE Vist, R Kunz, Y Falck-Ytter, P Alonso-Coello, et al.GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. Bmj. 2008; 336:924-6.
32. Egger, M, G Davey Smith, M SchneiderC Minder.Bias in meta-analysis detected by a simple, graphical test. Bmj. 1997; 315:629-34.
33. Tyrer, PD Baldwin.Generalised anxiety disorder. Lancet. 2006; 368:2156-66.
34. Dell'Osso, B, G Camuri, B Benatti, M BuoliAC Altamura.Differences in latency to first pharmacological treatment (duration of untreated illness) in anxiety disorders: a study on patients with panic disorder, generalized anxiety disorder and obsessive-compulsive disorder. Early Interv Psychiatry. 2013; 7:374-80.
35. Gersh, E, DJ Hallford, SM Rice, N Kazantzis, H Gersh, B Gersh, et al.Systematic review and meta-analysis of dropout rates in individual psychotherapy for generalized anxiety disorder. J Anxiety Disord. 2017; 52:25-33.
36. Dahlin, M, M Ryberg, K Vernmark, N Annas, P CarlbringG Andersson.Internet-delivered acceptance-based behavior therapy for generalized anxiety disorder: A pilot study. Internet Interv. 2016; 6:16-21.
37. Kanuri, N, MG Newman, JI Ruzek, E Kuhn, M Manjula, M Jones, et al.The Feasibility, Acceptability, and Efficacy of Delivering Internet-Based Self-Help and Guided Self-Help Interventions for Generalized Anxiety Disorder to Indian University Students: Design of a Randomized Controlled Trial. JMIR Res Protoc. 2015; 4:e136.
38. Dahlin, M, G Andersson, K Magnusson, T Johansson, J Sjögren, A Håkansson, et al.Internet-delivered acceptance-based behaviour therapy for generalized anxiety disorder: A randomized controlled trial. Behav Res Ther. 2016; 77:86-95.
39. Richards, D, L Timulak, C Rashleigh, O McLoughlin, A Colla, C Joyce, et al.Effectiveness of an internet-delivered intervention for generalized anxiety disorder in routine care: A randomised controlled trial in a student population. Internet Interv. 2016; 6:80-88.