Air quality is related to people's health. Severe air pollution can cause respiratory diseases, while good air quality is beneficial to physical and mental health. Therefore, the prediction of air quality is very important. As an important algorithm for signal analysis, empirical mode decomposition can analyze the change trend of air quality well, smooth the complex and changeable air quality data, and get the change trend of air quality under different time scales. According to the change trend under different time scales, the extreme learning machine is used for training, and the corresponding prediction value is obtained. The adaptive fuzzy inference system is used for fitting to obtain the final air quality prediction result. The experimental results show that the signal decomposition fuzzy prediction model has a good learning ability and has good accuracy in predicting the concentration of various pollutants in air quality.