This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research
Ng Yee Guan
37449-Putra Malaysia University
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
This study aims to calculate the intake of foods rich in CYP2E1 enzymes and glutathione to increase toluene detoxification.
Methods
The research design used was a cross sectional method. The research location is printing industry in Surabaya, East Java. The number of respondents was 30 workers of the printing industry. The calculated variables included body weight, work duration (years), work frequency per week (days), average workday (hours) of the respondent and benzene concentration. After all variables were obtained, respiration rate and carcinogenic detox benzene food intake per respondent were determined.
Results
All respondents who were at work showed benzene concentrations below the threshold value (TLV). Foods containing CYP2E1 enzyme included beef liver, salmon and fish oil while food with glutathione included grapes, avocados and asparagus.
Conclusion
Adequacy levels of CYP2E1 enzymes and glutathione are different and varied. The effective dose required by each respondent depends on body weight, length of work, and toluene concentration at work. In sum, the greater the toluene concentration, the greater the dietary needs which are rich in enzymes and CYP2E1 glutathione. Each respondent can choose benzene detox food depending on their needs and appetite.
Keywords
CYP2E1, detoxification, glutathione, toluene
Figure 1
Figure 2
Figure 3
Figure 4
Loading...
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 14 Sep, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Occupational Medicine
Learn more about our company.
This is a preprint. It has not completed peer review.
Research
Ng Yee Guan
37449-Putra Malaysia University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 14 Sep, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Occupational Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
This study aims to calculate the intake of foods rich in CYP2E1 enzymes and glutathione to increase toluene detoxification.
Methods
The research design used was a cross sectional method. The research location is printing industry in Surabaya, East Java. The number of respondents was 30 workers of the printing industry. The calculated variables included body weight, work duration (years), work frequency per week (days), average workday (hours) of the respondent and benzene concentration. After all variables were obtained, respiration rate and carcinogenic detox benzene food intake per respondent were determined.
Results
All respondents who were at work showed benzene concentrations below the threshold value (TLV). Foods containing CYP2E1 enzyme included beef liver, salmon and fish oil while food with glutathione included grapes, avocados and asparagus.
Conclusion
Adequacy levels of CYP2E1 enzymes and glutathione are different and varied. The effective dose required by each respondent depends on body weight, length of work, and toluene concentration at work. In sum, the greater the toluene concentration, the greater the dietary needs which are rich in enzymes and CYP2E1 glutathione. Each respondent can choose benzene detox food depending on their needs and appetite.
Figure 1
Figure 2
Figure 3
Figure 4
Loading...