This article presents a first attempt to carry out measurements (magnitudes and orientations) of the in situ stress in itabirite rocks in the region of the Brazilian Ferriferous Quadrilater obtained by hydraulic fracture tests at a depth of 399 m. Previous studies available in this rock mass consider estimated values of k index (Sh / Sv), and it is not a practice adopted to carry out in situ stress tests in this region and rockmass to support geotechnical analysis. The area of study is located at a depth of 500 m in a pit; therefore, the determination of the in situ stress distribution is very important to assess the stability of the mining open pit. The activities, from the planning to the execution of the tests, and the results are presented. The rock mass under study shows the presence of different geological structures, such as banding and foliation, which resulted in difficulties with performing the tests, and only 12.5% of the tests were successful. The results contribute to understanding the strains and stresses induced by mining activities in slopes in the Brazilian Ferriferous Quadrilater and their impacts on surrounding structures. For a better determination of the regional in situ stresses in the rock mass of the Brazilian Ferriferous Quadrilater, it is recommended to perform hydraulic tests on pre-existing fractures.