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Research note
Keneth Iceland Kasozi
Kampala International University - Western Campus
Corresponding Author
ORCiD: https://orcid.org/0000-0002-5763-7964
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Objective: Diabetes is associated with an upset of hematological and immunological parameters in humans, however information on the effects of Lycopene is scarce. The aim of the study was to gain information on basic changes in hematological parameters as markers for safety since anemia as a complication in diabetic chemotherapy has been reported. Results: Lycopene had anti-anemic effects and improved on the immune status of diabetic rats and these observations were dose independent. There was a decrease in neutrophil, low neutrophil-lymphocyte ratio and platelet counts and stable albumin, globulin levels. Lycopene could exert its protective effects through a balance of basic hematological physiological variables.
Keywords
Antioxidants, diabetes, anemia, Carotenoids, blood.
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CURRENT STATUS: Published
View the published article at BMC Research Notes.
Version 2
Posted 05 Dec, 2019
No community comments so far
Editorial decision: Accept
On 02 Dec, 2019
Editor assigned
On 30 Nov, 2019
Submission checks complete
On 29 Nov, 2019
Editor invited
On 29 Nov, 2019
No comments provided
Editorial decision: Major revision
On 10 Nov, 2019
Review #1 received
Received 04 Nov, 2019
Editor assigned
On 18 Oct, 2019
Reviewers invited
Invitations sent on 18 Oct, 2019
Reviewer #1 agreed
On 18 Oct, 2019
Submission checks complete
On 17 Oct, 2019
Editor invited
On 17 Oct, 2019
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Subject Areas
Gastroenterology & Hepatology
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A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
See the published version of this preprint at BMC Research Notes.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research note
Keneth Iceland Kasozi
Kampala International University - Western Campus
Corresponding Author
ORCiD: https://orcid.org/0000-0002-5763-7964
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Research Notes.
Version 2
Posted 05 Dec, 2019
No community comments so far
Editorial decision: Accept
On 02 Dec, 2019
Editor assigned
On 30 Nov, 2019
Submission checks complete
On 29 Nov, 2019
Editor invited
On 29 Nov, 2019
No comments provided
Editorial decision: Major revision
On 10 Nov, 2019
Review #1 received
Received 04 Nov, 2019
Editor assigned
On 18 Oct, 2019
Reviewers invited
Invitations sent on 18 Oct, 2019
Reviewer #1 agreed
On 18 Oct, 2019
Submission checks complete
On 17 Oct, 2019
Editor invited
On 17 Oct, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Gastroenterology & Hepatology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Research Notes.
Objective: Diabetes is associated with an upset of hematological and immunological parameters in humans, however information on the effects of Lycopene is scarce. The aim of the study was to gain information on basic changes in hematological parameters as markers for safety since anemia as a complication in diabetic chemotherapy has been reported. Results: Lycopene had anti-anemic effects and improved on the immune status of diabetic rats and these observations were dose independent. There was a decrease in neutrophil, low neutrophil-lymphocyte ratio and platelet counts and stable albumin, globulin levels. Lycopene could exert its protective effects through a balance of basic hematological physiological variables.
Figure 1
Figure 2
This is a list of supplementary files associated with this preprint. Click to download.
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