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Research article
Chaeseong Lim
Chungnam National University College of Medicine
Corresponding Author
ORCiD: https://orcid.org/0000-0002-2356-8999
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background Intravenous anesthesia has been reported to have a favorable effect on the prognosis of cancer patients. This study was performed to analyze data regarding the relation between anesthetics and the prognosis of cancer patients in our hospital.
Methods The medical records of patients who underwent surgical resection for gastric, lung, liver, colon, and breast cancer between January 2006 and December 2009 were reviewed. Depending on the type of anesthetic, it was divided into total intravenous anesthesia (TIVA) or volatile inhaled anesthesia (VIA) group. The 5-year overall survival outcomes were analyzed by log-rank test. Cox proportional hazards modeling was used for sensitivity.
Results The number of patients finally included in the comparison after propensity matching came to 729 in each group. The number of surviving patients at 5 years came to 660 (90.5%) in the TIVA and 673 (92.3%) in the VIA. The type of anesthetic did not affect the 5-year survival rate according to the log-rank test ( P = 0.21). Variables associated with a significant increase in the hazard of death after multivariable analysis were male sex and metastasis at surgery.
Conclusion There were no differences in 5-year overall survival between two groups in the cancer surgery.
Keywords
anesthesia, cancer, propofol, surgery, survival
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CURRENT STATUS: Published
View the published article at BMC Anesthesiology.
No community comments so far
Editorial decision: Accept
On 12 Dec, 2019
Review #1 received
Received 11 Dec, 2019
Review #2 received
Received 10 Dec, 2019
Reviewer #2 agreed
On 30 Nov, 2019
Reviewers invited
Invitations sent on 27 Nov, 2019
Reviewer #1 agreed
On 27 Nov, 2019
Editor assigned
On 26 Nov, 2019
Submission checks complete
On 25 Nov, 2019
Editor invited
On 25 Nov, 2019
Version 1
Posted 25 Oct, 2019
No comments provided
Review #3 received
Received 12 Nov, 2019
Editorial decision: Major revision
On 12 Nov, 2019
Review #2 received
Received 09 Nov, 2019
Review #1 received
Received 04 Nov, 2019
Reviewer #3 agreed
On 28 Oct, 2019
Reviewer #1 agreed
On 25 Oct, 2019
Reviewer #2 agreed
On 25 Oct, 2019
Reviewers invited
Invitations sent on 23 Oct, 2019
Editor assigned
On 15 Oct, 2019
Submission checks complete
On 14 Oct, 2019
Editor invited
On 14 Oct, 2019
Metrics
Comments: 0
PDF Downloads: ...
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Subject Areas
Anesthesiology & Pain Medicine
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A new preprint design is coming!
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See the published version of this preprint at BMC Anesthesiology.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Chaeseong Lim
Chungnam National University College of Medicine
Corresponding Author
ORCiD: https://orcid.org/0000-0002-2356-8999
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Anesthesiology.
No community comments so far
Editorial decision: Accept
On 12 Dec, 2019
Review #1 received
Received 11 Dec, 2019
Review #2 received
Received 10 Dec, 2019
Reviewer #2 agreed
On 30 Nov, 2019
Reviewers invited
Invitations sent on 27 Nov, 2019
Reviewer #1 agreed
On 27 Nov, 2019
Editor assigned
On 26 Nov, 2019
Submission checks complete
On 25 Nov, 2019
Editor invited
On 25 Nov, 2019
Version 1
Posted 25 Oct, 2019
No comments provided
Review #3 received
Received 12 Nov, 2019
Editorial decision: Major revision
On 12 Nov, 2019
Review #2 received
Received 09 Nov, 2019
Review #1 received
Received 04 Nov, 2019
Reviewer #3 agreed
On 28 Oct, 2019
Reviewer #1 agreed
On 25 Oct, 2019
Reviewer #2 agreed
On 25 Oct, 2019
Reviewers invited
Invitations sent on 23 Oct, 2019
Editor assigned
On 15 Oct, 2019
Submission checks complete
On 14 Oct, 2019
Editor invited
On 14 Oct, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Anesthesiology & Pain Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Anesthesiology.
Background Intravenous anesthesia has been reported to have a favorable effect on the prognosis of cancer patients. This study was performed to analyze data regarding the relation between anesthetics and the prognosis of cancer patients in our hospital.
Methods The medical records of patients who underwent surgical resection for gastric, lung, liver, colon, and breast cancer between January 2006 and December 2009 were reviewed. Depending on the type of anesthetic, it was divided into total intravenous anesthesia (TIVA) or volatile inhaled anesthesia (VIA) group. The 5-year overall survival outcomes were analyzed by log-rank test. Cox proportional hazards modeling was used for sensitivity.
Results The number of patients finally included in the comparison after propensity matching came to 729 in each group. The number of surviving patients at 5 years came to 660 (90.5%) in the TIVA and 673 (92.3%) in the VIA. The type of anesthetic did not affect the 5-year survival rate according to the log-rank test ( P = 0.21). Variables associated with a significant increase in the hazard of death after multivariable analysis were male sex and metastasis at surgery.
Conclusion There were no differences in 5-year overall survival between two groups in the cancer surgery.
Figure 1
Figure 2
Figure 3
Figure 4
This is a list of supplementary files associated with this preprint. Click to download.
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