Age/Sex
|
Glycaemic status
|
Other chronic illness
|
Previous Medications#
|
RT-PCR positivity for SARS-CoV-2
|
CT severity score (COVID)
|
Onset of symptoms of mucormycosis with respect to RT-PCR positivity
|
Symptoms pertaining to mucormycosis
|
Location of mucormycosis (CT imaging findings)
|
Intracranial involvement
|
Haematology parameters
|
Renal and liver function abnormalities if any
|
Fungal diagnosis confirmation
|
Management*
|
Steroid administered and dose/duration
|
Potential risk factors (Previously administered medications etc)
|
46/M
|
H/O Diabetes
HbA1c 9.6
|
Hypothyroidism
|
Glimepiride, Metformin, Thyroxine
|
Yes
|
7
|
30 days before
|
Nasal blockage, yellowish discharge, right cheek swelling, headache, right peri-orbital pain
|
Rt maxillary and rt ethmoid, sphenoid, and frontal sinusitis
|
No
|
Hb-9.5
TLC- 13300
(N66L27)
PLT- 350000
|
-
|
Broad aseptate hyphae on post-op tissue smear
|
Right endoscopic debridement of sinuses
|
Methylprednisolone 16 mg b.i.d x 5 days
|
Co-amoxiclav, ivermectin, zinc, vitamin C
|
33/M
|
Newly diagnosed DM
HbA1c 8.2
|
Dyslipidaemia
|
Metformin, Teneligliptin, Dapagliflozin, Fenofibrate, Rosuvastatin
|
No
|
15
|
-
|
Headache, right sided facial swelling
|
Right Maxillary, and sphenoid sinusitis
|
No
|
Hb-13.5
TLC- 10200 (N75L20)
PLT- 228000
|
-
|
Culture and HPE report awaited. CT report was suggestive of fungal sinusitis
|
Right endoscopic debridement of sinuses
|
Dexamethasone 6 mg b.i.d x 14 days; hydrocortisone 100 mg o.d x 2 days; methylprednisolone 8 mg o.d x 7 days
|
Remdesivir, meropenem, teicoplanin, faropenem, doxycycline, azithromycin, favipiravir, ivermectin, zinc, pirfenidone, vitamin C, oxygen
|
40/F
|
Newly diagnosed DM
HbA1c 9.2
|
None
|
Metformin, Glimepiride, Teneligliptin
|
Yes
|
-
|
9 days before
|
Pain and swelling right eye
|
Bilateral frontal, ethmoid, sphenoid (rt>lt) sinusitis; rt sided optic neuritis
|
Yes
|
Hb-10.5
TLC- 11230 (N68L25)
PLT- 330000
|
-
|
Broad aseptate hyphae on post-op tissue smear
|
Bilateral open debridement of sinuses along with orbital exenteration
|
None
|
Azithromycin, ivermectin, zinc
|
47/M
|
Newly diagnosed DM
HbA1c 6.8
|
Hypertension
|
Insulin 30/70 pre-mix, Amlodipine
|
Yes
|
-
|
16 days after
|
Right sided facial pain and swelling
|
Right maxillary and right ethmoid, sphenoid and frontal sinusitis
|
No
|
Hb-11.9
TLC- 6390 (N68L15)
PLT- 210000
|
Creatinine-2 Urea-49.5
|
Broad aseptate hyphae on pre-op smear; Mucor sp. on pre-op culture; granulomatous inflammation on HPE
|
Right endoscopic debridement of sinuses
|
Methylprednisolone 8 mg t.i.d tapered in 8 days
|
Cefixime, ofloxacin, azithromycin, clarithromycin, ivermectin, zinc, vitamin C
|
65/M
|
No dysglycaemia
HbA1c NA
|
Hypothyroidism
|
None
|
Yes
|
16
|
18 days before
|
Swelling both eye, headache
|
Bilateral frontal, maxillary, ethmoid, and sphenoid sinusitis
|
No
|
Hb-9.6
TLC- 6800 (N58L36)
PLT- 141000
|
-
|
Broad, aseptate hyphae on post-op tissue smear
|
Bilateral open debridement of sinuses
|
Methylprednisolone 40 mg t.i.d x 5 days; tapered in 20 days
|
Azithromycin, moxifloxacin, levofloxacin, meropenem, doxycycline, vitamin C, ivermectin, zinc, fluconazole, oxygen
|
53/F
|
H/O Diabetes
HbA1c 8.7
|
Hypertension
|
Metformin, Telmisartan, Warfarin
|
Yes
|
-
|
4 days after
|
Facial pain and swelling
|
Rt maxillary, ethmoid, and sphenoid sinusitis
|
No
|
Hb-8
TLC- 3200 (N55L37)
PLT- 207000
|
-
|
Broad, aseptate hyphae on pre-op smear; Rhizopus sp. on pre-op culture; HPE suggestive of mucormycosis
|
Right sided open debridement of sinuses along with inferior maxillectomy
|
Dexamethasone 6 mg b.i.d x 12 days
|
Ceftriaxone, cefpodoxime, favipiravir, vitamin C, oxygen
|
62/M
|
Newly diagnosed DM
HbA1c 8.5
|
Hypertension
|
Telmisartan, Amlodipine
|
Yes
|
-
|
10 days after
|
Left sided facial swelling, purulent discharge left eye
|
Lt maxillary, ethmoid, frontal sinusitis; mild erosion of lt lamina papyracea
|
No
|
Hb-13
TLC- 14600 (N78L17)
PLT- 174000
|
-
|
Broad, aseptate hyphae on pre-op smear; aseptate hyphae on post-op tissue smear; HPE suggestive of mucormycosis
|
Left sided open debridement of sinuses
|
Dexamethasone 6 mg o.d x 12 days; methylprednisolone 125 mg o.d x 2 days
|
Methylprednisolone, meropenem, ivermectin, zinc, itraconazole, vitamin C, oxygen
|
58/M
|
Newly diagnosed DM
HbA1c 14.7
|
None
|
None
|
Yes
|
-
|
2 days before
|
Headache, vomiting, right eye pain, delirium
|
Rt maxillary, sphenoid, bilateral ethmoid sinusitis; acute infarct rt fronto-parietal lobe
|
Yes
|
Hb-14.4
TLC- 8670 (N71L18)
PLT- 243000
|
-
|
Broad, aseptate hyphae on post-op tissue smear
|
Right sided open debridement of sinuses
|
Dexamethasone 4 mg o.d x 5 days
|
Doxycycline, azithromycin, ivermectin, ashwagandha (Ayurvedic)
|
40/M
|
Newly diagnosed DM
HbA1c 13.5
|
None
|
None
|
Yes
|
13
|
18 days after
|
Headache, facial swelling, and pain
|
Bilateral ethmoid, sphenoid, maxillary sinusitis; extensive orbital and intracranial involvement
|
Yes
|
Hb-13
TLC- 14700 (N86L7)
PLT- 300000
|
-
|
Culture and HPE report awaited; CT features suggestive of sinusitis with extensive intracranial involvement
|
Bilateral open debridement of sinuses, orbital exenteration and craniotomy along with decompression of posterior fossa
|
Dexamethasone 8 mg o.d x 10 days
|
Gentamicin, meropenem, linezolid
|
60/M
|
H/O Diabetes
HbA1c 8.5
|
Hypertension
|
Metformin, Glimepiride, Telmisartan
|
Yes
|
-
|
5 days after
|
Right facial pain and swelling
|
Rt frontal, ethmoidal sinusitis; soft tissue edema in rt periorbital region
|
No
|
Hb-11.2
TLC- 10600 (N70L20)
PLT- 226000
|
Creatinine-1.4
Urea-83
|
Broad, aseptate hyphae on post-op tissue smear
|
Right sided open debridement of sinuses along with orbital decompression
|
Prednisolone 30 mg o.d x 5 days; tapered in 25 days
|
Doxycycline, azithromycin, cefuroxime, vitamin D high dose, ivermectin, zinc, vitamin C, oxygen
|
65/M
|
Newly diagnosed DM
HbA1c 7
|
Hypertension, CAD
|
Cilnidipine, Clopidogrel, Rosuvastatin, Isosorbide dinitrate, Tamsulosin, Dutasteride
|
Yes
|
8
|
5 days after
|
Headache, facial pain, eye discharge
|
Bilateral maxillary, ethmoid, and sphenoid sinusitis; rt orbital cellulitis
|
No
|
Hb-10.8
TLC- 5140 (N90L10)
PLT- 185000
|
-
|
Fragmented hyphae on post-op tissue smear; CT features of sinus involvement with orbital cellulitis
|
Bilateral open debridement of sinuses and orbital exenteration
|
Dexamethasone 2 mg t.i.d x 5 days
|
Co-amoxiclav, cefixime, ivermectin, zinc, vitamin C.
Patient received 1 dose of COVAXIN (inactivated SARS-CoV-2 vaccine)
|
42/M
|
Newly diagnosed DM
HbA1c 10.8
|
None
|
Insulin
|
Yes
|
19
|
12 days after
|
Facial swelling and pain, right eye swelling
|
Rt maxillary, sphenoid and ethmoid sinusitis; with right eye involvement
|
No
|
Hb-9.2
TLC-7060
(N69L20)
PLT-190000
|
Creatinine-2
Urea-45
|
Culture and HPE report awaited; CT features suggestive
|
Right open debridement of sinuses along with orbital decompression
|
Prednisolone 40 mg o.d x 5 days; methylprednisolone 8 mg t.i.d x 5 days followed by 16 mg o.d x 5 days
|
Piperacillin-tazobactam, cefuroxime, zinc, vitamin C
|
58/F
|
H/O Diabetes
HbA1c 12.2
|
None
|
None
|
Yes
|
14
|
4 days after
|
Left facial swelling, left eye swelling
|
Lt maxillary, ethmoid sinusitis; lt orbital cellulitis; possible cavernous sinus thrombosis
|
Yes
|
Hb-7.7
TLC-16030
(N80L10)
PLT-278000
|
-
|
Broad, aseptate hyphae on post-op tissue smear
|
Left open debridement of sinuses and orbital exenteration
|
Unknown status
|
Doxycycline, azithromycin, ivermectin, zinc, vitamin C, oxygen.
Patient received both doses of COVISHIELD (recombinant adenoviral vaccine for COVID), second dose 1 day before PCR positivity
|