This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research
Abdul Rohim Tualeka
Universitas Airlangga
Corresponding Author
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Introduction. The use of BTX as a solvent in the production process potentially causes negative impact on workers, especially on DNA degeneration and MDA levels in workers of industrial sector.
Aims. This study aims to determine the relationship between concentration, RQ and ECR of BTX, MDA levelsand DNA degeneration in industrial workers exposed to BTX in Surabaya.
Method. This research was conducted in industries in Surabaya that use BTX as a solvent in its production process. It was conducted in Ketintang, Jemursari, Kalijudan, AUP and Romokalisari. The research design used was cross sectional with 81 samples. The variables studied in this study were the concentration, RQ, ECR of BTX, MDA and DNA degeneration. The data were analyzed using the Pearson correlation test.
Result. There was a relationship between the concentration of benzene, toluene and MDA level in workers exposed to BTX with a P value <0.05. There was a relationship between the concentration of toluene, ECR of toluene and DNA degeneration in workers exposed to BTX in the industry in Surabaya with a P value <0.05.
Conclusion. There was a relationship between the concentrations of benzene, toluene and MDA levelsin workers exposed to BTX. There was a relationship between toluene concentrations, ECR of toluene and DNA degeneration in workers exposed to BTX.
Keywords
BTX, DNA degeneration, MDA, RQ, ECR
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research
Abdul Rohim Tualeka
Universitas Airlangga
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 17 Sep, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Introduction. The use of BTX as a solvent in the production process potentially causes negative impact on workers, especially on DNA degeneration and MDA levels in workers of industrial sector.
Aims. This study aims to determine the relationship between concentration, RQ and ECR of BTX, MDA levelsand DNA degeneration in industrial workers exposed to BTX in Surabaya.
Method. This research was conducted in industries in Surabaya that use BTX as a solvent in its production process. It was conducted in Ketintang, Jemursari, Kalijudan, AUP and Romokalisari. The research design used was cross sectional with 81 samples. The variables studied in this study were the concentration, RQ, ECR of BTX, MDA and DNA degeneration. The data were analyzed using the Pearson correlation test.
Result. There was a relationship between the concentration of benzene, toluene and MDA level in workers exposed to BTX with a P value <0.05. There was a relationship between the concentration of toluene, ECR of toluene and DNA degeneration in workers exposed to BTX in the industry in Surabaya with a P value <0.05.
Conclusion. There was a relationship between the concentrations of benzene, toluene and MDA levelsin workers exposed to BTX. There was a relationship between toluene concentrations, ECR of toluene and DNA degeneration in workers exposed to BTX.
Figure 1
Figure 2
Figure 3
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