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Research
Clinico-Pathological Findings and Spatial Distributions of Esophageal Cancer in Arsi Zone, Central Ethiopia
Haji Aman Deybasso
Jimma University
Corresponding Author
ORCiD: https://orcid.org/0000-0003-1441-3300
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Arsi Zone is one of the esophageal cancer endemic areas and reported to have high incidence of esophageal cancer in Ethiopia. This study assessed clinico-pathological patterns and spatial distributions of esophageal cancer in Arsi Zone, Oromia, Central Ethiopia.
Methods: A cross sectional study design was carried out by abstracting data from 403 patients` records that were treated from January 2015 to January 2019. Data were collected by using structured data collection form and Geographical Positioning System software. The collected data were summarized in the form of tables, figures, means and standard deviations. Statistical data analysis was done using SPSS software version 21.0 while geospatial analysis was conducted using the Arc-GIS 10.1 software.
Results: The disease was prominent among individuals aged 50 to 59 years. The mean age of females and males was 52.2(SD+10.41) and 56.94(SD +12.27) years respectively. The vast majority (98.3%) of the cases had squamous cell carcinoma. Dysphagia with weight loss accounted for 87.6 percent of the presenting symptoms. The tumor was located at the lower thorax of 42.9% of the patients. Majority (62%) of the patients were from the eastern and north-eastern parts of the Arsi zone. Overwhelming majorities of the patients were from the Robe, Jaju, Disksis and Sude districts.
Conclusion: Dysphagia with weight loss was the major symptom during first visit. Squamous cell carcinoma was the predominant histopathological type. Eastern and the northeastern parts of the Zone are the most affected regions. Future studies should focus on the determinants of EC and precise areas with high incidence by using prospective studies through the population and/or facility-based cancer registry systems
Keywords
Esophageal cancer, clinical pattern, geographical distribution, Arsi, Ethiopia
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S J van Rensburg
commented on 15 November, 2020
An informative analysis of the situation in Ethiopia; it lends further weight to current concepts on geographic determinants of incidence. Worldwide high incidence in rural populations is always associated with geological strata that give rise to soils and water that are deficient in a few micronutrients that are essential to the integrity of the esophagus. The verified sequence of events in open access review DOI: 10.3892/wasj.2019.24
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Research
Clinico-Pathological Findings and Spatial Distributions of Esophageal Cancer in Arsi Zone, Central Ethiopia
Haji Aman Deybasso
Jimma University
Corresponding Author
ORCiD: https://orcid.org/0000-0003-1441-3300
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 23 Sep, 2020
Community comments: 1
Metrics
Comments: 1
PDF Downloads: ...
HTML Views: ...
Subject Areas
Oncology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Arsi Zone is one of the esophageal cancer endemic areas and reported to have high incidence of esophageal cancer in Ethiopia. This study assessed clinico-pathological patterns and spatial distributions of esophageal cancer in Arsi Zone, Oromia, Central Ethiopia.
Methods: A cross sectional study design was carried out by abstracting data from 403 patients` records that were treated from January 2015 to January 2019. Data were collected by using structured data collection form and Geographical Positioning System software. The collected data were summarized in the form of tables, figures, means and standard deviations. Statistical data analysis was done using SPSS software version 21.0 while geospatial analysis was conducted using the Arc-GIS 10.1 software.
Results: The disease was prominent among individuals aged 50 to 59 years. The mean age of females and males was 52.2(SD+10.41) and 56.94(SD +12.27) years respectively. The vast majority (98.3%) of the cases had squamous cell carcinoma. Dysphagia with weight loss accounted for 87.6 percent of the presenting symptoms. The tumor was located at the lower thorax of 42.9% of the patients. Majority (62%) of the patients were from the eastern and north-eastern parts of the Arsi zone. Overwhelming majorities of the patients were from the Robe, Jaju, Disksis and Sude districts.
Conclusion: Dysphagia with weight loss was the major symptom during first visit. Squamous cell carcinoma was the predominant histopathological type. Eastern and the northeastern parts of the Zone are the most affected regions. Future studies should focus on the determinants of EC and precise areas with high incidence by using prospective studies through the population and/or facility-based cancer registry systems
Figure 1
Figure 2
S J van Rensburg
commented on 15 November, 2020
An informative analysis of the situation in Ethiopia; it lends further weight to current concepts on geographic determinants of incidence. Worldwide high incidence in rural populations is always associated with geological strata that give rise to soils and water that are deficient in a few micronutrients that are essential to the integrity of the esophagus. The verified sequence of events in open access review DOI: 10.3892/wasj.2019.24