See the published version of this preprint at BMC Ophthalmology.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
Research article
Hiroyuki Nakashizuka
Nihon University hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5801-8893
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Backgroud: To evaluate the efficacy of epiretinal membrane removal in patients with good best-corrected visual acuity (BCVA) for improving visual function and quality of life (QOL). Methods: This prospective case study compared 37 subjects with preoperative BCVA ≦ 0.046 logMAR (Good group) to 35 patients with 0.10 - 0.52 logMAR (Moderate group) at 3 and 6 months. Linear mixed-effect models were used for statistical analysis. The primary outcome was the horizontal metamorphopsia score (MH) at 6 months postoperatively (post-6 M), while secondary outcomes were postoperative BCVA, vertical metamorphopsia score (MV), aniseikonia, stereopsis and central foveal thickness. In the Good group, QOL was assessed using the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) at 6 and 12 months. Results: MH was significantly improved at post-3 M and post-6 M in the both groups but there were no significant differences between the two groups. MV showed no improvement at the final observation in either group. LogMAR BCVA was significantly improved at post-6 M in the Good group, which had significantly better vision than the Moderate group. Preoperative vertical and horizontal aniseikonia scores remained unchanged in the Good group at post-6 M but worsened in the Moderate group. The NEI VFQ-25 score improved in the Good group, reflecting improved general health, general vision, and mental health. Conclusions: Early epiretinal surgery for patients with BCVA ≦ 0.046 logMAR was effective for improvement of HM, BCVA, and QOL and prevented worsening of aniseikonia.
Keywords
epiretinal membrane, good visual acuity, metamorphopsia, aniseikonia, vitrectomy
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Loading...
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Ophthalmology.
No community comments so far
Submission checks complete
On 07 Nov, 2019
Editorial decision: Accept
On 26 Jul, 2019
Version 3
Posted 30 Jul, 2019
No comments provided
Editorial decision: Minor revision
On 16 Jul, 2019
Editor assigned
On 15 Jul, 2019
Submission checks complete
On 14 Jul, 2019
Editor invited
On 14 Jul, 2019
No comments provided
Editorial decision: Minor revision
On 11 Jul, 2019
Review #2 received
Received 01 Jul, 2019
Reviewers invited
Invitations sent on 23 Jun, 2019
Reviewer #1 agreed
On 23 Jun, 2019
Reviewer #2 agreed
On 23 Jun, 2019
Review #1 received
Received 23 Jun, 2019
Submission checks complete
On 20 Jun, 2019
Editor invited
On 20 Jun, 2019
Editor assigned
On 20 Jun, 2019
No comments provided
Editorial decision: Major revision
On 29 May, 2019
Review #1 received
Received 28 May, 2019
Reviewer #2 agreed
On 18 May, 2019
Review #2 received
Received 18 May, 2019
Reviewers invited
Invitations sent on 17 May, 2019
Reviewer #1 agreed
On 17 May, 2019
Submission checks complete
On 04 May, 2019
Editor invited
On 04 May, 2019
Editor assigned
On 04 May, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Internal Medicine
Learn more about our company.
A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
See the published version of this preprint at BMC Ophthalmology.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Hiroyuki Nakashizuka
Nihon University hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5801-8893
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Ophthalmology.
No community comments so far
Submission checks complete
On 07 Nov, 2019
Editorial decision: Accept
On 26 Jul, 2019
Version 3
Posted 30 Jul, 2019
No comments provided
Editorial decision: Minor revision
On 16 Jul, 2019
Editor assigned
On 15 Jul, 2019
Submission checks complete
On 14 Jul, 2019
Editor invited
On 14 Jul, 2019
No comments provided
Editorial decision: Minor revision
On 11 Jul, 2019
Review #2 received
Received 01 Jul, 2019
Reviewers invited
Invitations sent on 23 Jun, 2019
Reviewer #1 agreed
On 23 Jun, 2019
Reviewer #2 agreed
On 23 Jun, 2019
Review #1 received
Received 23 Jun, 2019
Submission checks complete
On 20 Jun, 2019
Editor invited
On 20 Jun, 2019
Editor assigned
On 20 Jun, 2019
No comments provided
Editorial decision: Major revision
On 29 May, 2019
Review #1 received
Received 28 May, 2019
Reviewer #2 agreed
On 18 May, 2019
Review #2 received
Received 18 May, 2019
Reviewers invited
Invitations sent on 17 May, 2019
Reviewer #1 agreed
On 17 May, 2019
Submission checks complete
On 04 May, 2019
Editor invited
On 04 May, 2019
Editor assigned
On 04 May, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Internal Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Ophthalmology.
Backgroud: To evaluate the efficacy of epiretinal membrane removal in patients with good best-corrected visual acuity (BCVA) for improving visual function and quality of life (QOL). Methods: This prospective case study compared 37 subjects with preoperative BCVA ≦ 0.046 logMAR (Good group) to 35 patients with 0.10 - 0.52 logMAR (Moderate group) at 3 and 6 months. Linear mixed-effect models were used for statistical analysis. The primary outcome was the horizontal metamorphopsia score (MH) at 6 months postoperatively (post-6 M), while secondary outcomes were postoperative BCVA, vertical metamorphopsia score (MV), aniseikonia, stereopsis and central foveal thickness. In the Good group, QOL was assessed using the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) at 6 and 12 months. Results: MH was significantly improved at post-3 M and post-6 M in the both groups but there were no significant differences between the two groups. MV showed no improvement at the final observation in either group. LogMAR BCVA was significantly improved at post-6 M in the Good group, which had significantly better vision than the Moderate group. Preoperative vertical and horizontal aniseikonia scores remained unchanged in the Good group at post-6 M but worsened in the Moderate group. The NEI VFQ-25 score improved in the Good group, reflecting improved general health, general vision, and mental health. Conclusions: Early epiretinal surgery for patients with BCVA ≦ 0.046 logMAR was effective for improvement of HM, BCVA, and QOL and prevented worsening of aniseikonia.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Loading...