1.Wesselink EM, Kappen TH, Torn HM, Slooter AJC, van Klei WA. Intraoperative hypotension and the risk of postoperative adverse outcomes: a systematic review. British journal of anaesthesia. 2018;121(4):706–21.
2.Ahmad M, Dar NJ, Bhat ZS, Hussain A, Shah A, Liu H, et al. Inflammation in ischemic stroke: mechanisms, consequences and possible drug targets. CNS & neurological disorders drug targets. 2014;13(8):1378–96.
3.Ng JL, Chan MT, Gelb AW. Perioperative stroke in noncardiac, nonneurosurgical surgery. Anesthesiology. 2011;115(4):879–90.
4.Moretti A, Ferrari F, Villa RF. Neuroprotection for ischaemic stroke: current status and challenges. Pharmacology & therapeutics. 2015;146:23–34.
5.Ulbrich F, Schallner N, Coburn M, Loop T, Lagreze WA, Biermann J, et al. Argon inhalation attenuates retinal apoptosis after ischemia/reperfusion injury in a time- and dose-dependent manner in rats. PloS one. 2014;9(12):e115984.
6.Ulbrich F, Kaufmann KB, Coburn M, Lagreze WA, Roesslein M, Biermann J, et al. Neuroprotective effects of Argon are mediated via an ERK–1/2 dependent regulation of heme-oxygenase–1 in retinal ganglion cells. Journal of neurochemistry. 2015;134(4):717–27.
7.Soldatov PE, D’Iachenko A I, Pavlov BN, Fedotov AP, Chuguev AP. [Survival of laboratory animals in argon-containing hypoxic gaseous environments]. Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. 1998;32(4):33–7.
8.Loetscher PD, Rossaint J, Rossaint R, Weis J, Fries M, Fahlenkamp A, et al. Argon: neuroprotection in in vitro models of cerebral ischemia and traumatic brain injury. Critical care (London, England). 2009;13(6):R206.
9.Ryang YM, Fahlenkamp AV, Rossaint R, Wesp D, Loetscher PD, Beyer C, et al. Neuroprotective effects of argon in an in vivo model of transient middle cerebral artery occlusion in rats. Critical care medicine. 2011;39(6):1448–53.
10.David HN, Haelewyn B, Degoulet M, Colomb DG, Jr., Risso JJ, Abraini JH. Ex vivo and in vivo neuroprotection induced by argon when given after an excitotoxic or ischemic insult. PloS one. 2012;7(2):e30934.
11.Fahlenkamp AV, Rossaint R, Haase H, Al Kassam H, Ryang YM, Beyer C, et al. The noble gas argon modifies extracellular signal-regulated kinase 1/2 signaling in neurons and glial cells. European journal of pharmacology. 2012;674(2–3):104–11.
12.Brucken A, Kurnaz P, Bleilevens C, Derwall M, Weis J, Nolte K, et al. Dose dependent neuroprotection of the noble gas argon after cardiac arrest in rats is not mediated by K(ATP)-channel opening. Resuscitation. 2014;85(6):826–32.
13.Zhuang L, Yang T, Zhao H, Fidalgo AR, Vizcaychipi MP, Sanders RD, et al. The protective profile of argon, helium, and xenon in a model of neonatal asphyxia in rats. Critical care medicine. 2012;40(6):1724–30.
14.Ulbrich F, Kaufmann K, Roesslein M, Wellner F, Auwarter V, Kempf J, et al. Argon Mediates Anti-Apoptotic Signaling and Neuroprotection via Inhibition of Toll-Like Receptor 2 and 4. PloS one. 2015;10(12):e0143887.
15.Mouihate A, Mehdawi H. Toll-like receptor 4-mediated immune stress in pregnant rats activates STAT3 in the fetal brain: role of interleukin–6. Pediatric research. 2016;79(5):781–7.
16.Przanowski P, Dabrowski M, Ellert-Miklaszewska A, Kloss M, Mieczkowski J, Kaza B, et al. The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia. Journal of molecular medicine (Berlin, Germany). 2014;92(3):239–54.
17.Xiong XY, Liu L, Yang QW. Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke. Progress in neurobiology. 2016;142:23–44.
18.Liu J, Nolte K, Brook G, Liebenstund L, Weinandy A, Hollig A, et al. Post-stroke treatment with argon attenuated brain injury, reduced brain inflammation and enhanced M2 microglia/macrophage polarization: a randomized controlled animal study. Critical care (London, England). 2019;23(1):198.
19.Ulbrich F, Kaufmann KB, Coburn M, Lagreze WA, Roesslein M, Biermann J, et al. Neuroprotective effects of Argon are mediated via an ERK–1/2 dependent regulation of heme-oxygenase–1 in retinal ganglion cells. Journal of neurochemistry. 2015.
20.Biermann J, Lagreze WA, Dimitriu C, Stoykow C, Goebel U. Preconditioning with inhalative carbon monoxide protects rat retinal ganglion cells from ischemia/reperfusion injury. Investigative ophthalmology & visual science. 2010;51(7):3784–91.
21.Noailles A, Fernandez-Sanchez L, Lax P, Cuenca N. Microglia activation in a model of retinal degeneration and TUDCA neuroprotective effects. Journal of neuroinflammation. 2014;11:186.
22.Chen H, Yoshioka H, Kim GS, Jung JE, Okami N, Sakata H, et al. Oxidative stress in ischemic brain damage: mechanisms of cell death and potential molecular targets for neuroprotection. Antioxidants & redox signaling. 2011;14(8):1505–17.
23.Jiang S, Deng C, Lv J, Fan C, Hu W, Di S, et al. Nrf2 Weaves an Elaborate Network of Neuroprotection Against Stroke. Molecular neurobiology. 2017;54(2):1440–55.
24.Chen Z, Trapp BD. Microglia and neuroprotection. Journal of neurochemistry. 2016;136 Suppl 1:10–7.
25.Ulbrich F, Lerach T, Biermann J, Kaufmann KB, Lagreze WA, Buerkle H, et al. Argon mediates protection by Interleukin–8 suppression via a TLR2/TLR4/STAT3/NF-kappaB pathway in a model of apoptosis in neuroblastoma cells in-vitro and following ischemia-reperfusion injury in rat retina in-vivo. Journal of neurochemistry. 2016.
26.Dziennis S, Alkayed NJ. Role of signal transducer and activator of transcription 3 in neuronal survival and regeneration. Reviews in the neurosciences. 2008;19(4–5):341–61.
27.Ito M, Komai K, Mise-Omata S, Iizuka-Koga M, Noguchi Y, Kondo T, et al. Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery. Nature. 2019;565(7738):246–50.
28.Hwang JW, Jeon YT, Lim YJ, Park HP. Sevoflurane Postconditioning-Induced Anti-Inflammation via Inhibition of the Toll-Like Receptor–4/Nuclear Factor Kappa B Pathway Contributes to Neuroprotection against Transient Global Cerebral Ischemia in Rats. International journal of molecular sciences. 2017;18(11).
29.Nalamolu KR, Smith NJ, Chelluboina B, Klopfenstein JD, Pinson DM, Wang DZ, et al. Prevention of the Severity of Post-ischemic Inflammation and Brain Damage by Simultaneous Knockdown of Toll-like Receptors 2 and 4. Neuroscience. 2018;373:82–91.
30.Lee JM, Li J, Johnson DA, Stein TD, Kraft AD, Calkins MJ, et al. Nrf2, a multi-organ protector? FASEB journal: official publication of the Federation of American Societies for Experimental Biology. 2005;19(9):1061–6.
31.Zhao H, Mitchell S, Ciechanowicz S, Savage S, Wang T, Ji X, et al. Argon protects against hypoxic-ischemic brain injury in neonatal rats through activation of nuclear factor (erythroid-derived 2)-like 2. Oncotarget. 2016;7(18):25640–51.
32.Herdegen T, Waetzig V. AP–1 proteins in the adult brain: facts and fiction about effectors of neuroprotection and neurodegeneration. Oncogene. 2001;20(19):2424–37.
33.Qi SH, Liu Y, Hao LY, Guan QH, Gu YH, Zhang J, et al. Neuroprotection of ethanol against ischemia/reperfusion-induced brain injury through decreasing c-Jun N-terminal kinase 3 (JNK3) activation by enhancing GABA release. Neuroscience. 2010;167(4):1125–37.
34.Planas AM, Soriano MA, Berruezo M, Justicia C, Estrada A, Pitarch S, et al. Induction of Stat3, a signal transducer and transcription factor, in reactive microglia following transient focal cerebral ischaemia. The European journal of neuroscience. 1996;8(12):2612–8.
35.Lee M. Neurotransmitters and microglial-mediated neuroinflammation. Current protein & peptide science. 2013;14(1):21–32.
36.Hui B, Zhang L, Zhou Q, Hui L. Pristimerin Inhibits LPS-Triggered Neurotoxicity in BV–2 Microglia Cells Through Modulating IRAK1/TRAF6/TAK1-Mediated NF-kappaB and AP–1 Signaling Pathways In Vitro. Neurotoxicity research. 2018;33(2):268–83.
37.Vilhardt F, Haslund-Vinding J, Jaquet V, McBean G. Microglia antioxidant systems and redox signalling. British journal of pharmacology. 2017;174(12):1719–32.
38.Fahlenkamp AV, Coburn M, de Prada A, Gereitzig N, Beyer C, Haase H, et al. Expression analysis following argon treatment in an in vivo model of transient middle cerebral artery occlusion in rats. Medical gas research. 2014;4:11.
39.Collmann FM, Pijnenburg R, Hamzei-Taj S, Minassian A, Folz-Donahue K, Kukat C, et al. Individual in vivo Profiles of Microglia Polarization After Stroke, Represented by the Genes iNOS and Ym1. Frontiers in immunology. 2019;10:1236.