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Case Report
Human pathogenic Mycobacterium kansasii (former subtype I) with zoonotic potential isolated from a diseased indoor pet cat, Japan
Yoshihiko Hoshino
National Institute of Infectious Diseases
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3132-0715
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This work is licensed under a CC BY 4.0 License. Read Full License
Declarations:
Declarations
- This study involved the use of non-human vertebrates.
- The author has confirmed that all appropriate ethical guidelines for the handling and use of animals in research have been followed and details of the oversight board have been included in the text.
- The author has confirmed that a statement listing potential conflicts of interest or lack thereof is included in the text.
Mycobacterium kansasii is one of the most prevalent and pathogenic nontuberculous mycobacteria in the world. Herein, we report the first case of M. kansasii infection in an indoor domestic cat in Japan. Complete genome sequence analysis of the isolate showed this pathogen is genetically identical to human pathogenic M. kansasii.
Keywords
Mycobacterium kansasii, Emerging Infectious Diseases, Zoonoses, Diseases Reservoirs, Nontuberculous Mycobacteria
Figure 1
Figure 2
This is a list of supplementary files associated with this preprint. Click to download.
- TechnicalAppendix.docx
- AppendixFig.1Pangenome.png
Appendix Figure 1: Gene presence (blue) -absence (white) matrix showing the distribution of core and accessory genes for 17 M. kansasii strains.
- AppendixFig.2ACDoperon.png
Appendix Figure 2: Comparison of espACD operon between feline isolate Kuro-I and M. kansasii ATCC12478T.
- AppendixFig.3ANI.png
Appendix Figure 3: Heat map of average nucleotide identity (ANI) values.
- AppendixTable.xlsx
Appendix Table: Information list of strains used in this study 32 strains of M. kansasii complex were collected by NCBI Assembly or SRA databases. The host and isolation sources were extracted from tied BioSample databases.
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This is a preprint. It has not completed peer review.
Case Report
Human pathogenic Mycobacterium kansasii (former subtype I) with zoonotic potential isolated from a diseased indoor pet cat, Japan
Yoshihiko Hoshino
National Institute of Infectious Diseases
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3132-0715
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 28 Sep, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Bacteriology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Declarations:
Declarations
- This study involved the use of non-human vertebrates.
- The author has confirmed that all appropriate ethical guidelines for the handling and use of animals in research have been followed and details of the oversight board have been included in the text.
- The author has confirmed that a statement listing potential conflicts of interest or lack thereof is included in the text.
Mycobacterium kansasii is one of the most prevalent and pathogenic nontuberculous mycobacteria in the world. Herein, we report the first case of M. kansasii infection in an indoor domestic cat in Japan. Complete genome sequence analysis of the isolate showed this pathogen is genetically identical to human pathogenic M. kansasii.
Figure 1
Figure 2