1 Liu, W. et al. Long non-coding RNA MALAT1 contributes to cell apoptosis by sponging miR-124 in Parkinson disease. Cell Biosci7, 19, doi:10.1186/s13578-017-0147-5 (2017).
2 Dexter, D. T. & Jenner, P. Parkinson disease: from pathology to molecular disease mechanisms. Free Radic Biol Med62, 132-144, doi:10.1016/j.freeradbiomed.2013.01.018 (2013).
3 Scheperjans, F. et al. Gut microbiota are related to Parkinson's disease and clinical phenotype. Mov Disord30, 350-358, doi:10.1002/mds.26069 (2015).
4 Jang, W. et al. The Neuroprotective Effect of Erythropoietin on Rotenone-Induced Neurotoxicity in SH-SY5Y Cells Through the Induction of Autophagy. Mol Neurobiol53, 3812-3821, doi:10.1007/s12035-015-9316-x (2016).
5 Zhu, J. et al. Apelin-36 mediates neuroprotective effects by regulating oxidative stress, autophagy and apoptosis in MPTP-induced Parkinson's disease model mice. Brain Res1726, 146493, doi:10.1016/j.brainres.2019.146493 (2020).
6 Baluchnejadmojarad, T., Mansouri, M., Ghalami, J., Mokhtari, Z. & Roghani, M. Sesamin imparts neuroprotection against intrastriatal 6-hydroxydopamine toxicity by inhibition of astroglial activation, apoptosis, and oxidative stress. Biomed Pharmacother88, 754-761, doi:10.1016/j.biopha.2017.01.123 (2017).
7 Cherra, S. J., 3rd & Chu, C. T. Autophagy in neuroprotection and neurodegeneration: A question of balance. Future Neurol3, 309-323, doi:10.2217/14796708.3.3.309 (2008).
8 Gorman, A. M., McGowan, A., O'Neill, C. & Cotter, T. Oxidative stress and apoptosis in neurodegeneration. Journal of the neurological sciences139 Suppl, 45-52, doi:10.1016/0022-510x(96)00097-4 (1996).
9 Chi, H., Guan, Y., Li, F. & Chen, Z. The Effect of Human Umbilical Cord Mesenchymal Stromal Cells in Protection of Dopaminergic Neurons from Apoptosis by Reducing Oxidative Stress in the Early Stage of a 6-OHDA-Induced Parkinson's Disease Model. Cell Transplant28, 87S-99S, doi:10.1177/0963689719891134 (2019).
10 Klionsky, D. J. & Emr, S. D. Autophagy as a regulated pathway of cellular degradation. Science290, 1717-1721, doi:10.1126/science.290.5497.1717 (2000).
11 Xie, Q., Liu, M., Yan, Y. F., Shen, X. & Wang, E. S. Exogenous Tetranectin Protects Against 1-Methyl-4-Phenylpyridine-Induced Neurotoxicity by Inhibiting Apoptosis and Autophagy Through Ribosomal Protein S6 Kinase Beta-1. World Neurosurg122, e375-e382, doi:10.1016/j.wneu.2018.10.058 (2019).
12 Tuohetaerbaike, B. et al. Pancreas protective effects of Urolithin A on type 2 diabetic mice induced by high fat and streptozotocin via regulating autophagy and AKT/mTOR signaling pathway. J Ethnopharmacol250, 112479, doi:10.1016/j.jep.2019.112479 (2020).
13 Onorati, A. V., Dyczynski, M., Ojha, R. & Amaravadi, R. K. Targeting autophagy in cancer. Cancer124, 3307-3318, doi:10.1002/cncr.31335 (2018).
14 Cui, L. & Su, X. Z. Discovery, mechanisms of action and combination therapy of artemisinin. Expert Rev Anti Infect Ther7, 999-1013, doi:10.1586/eri.09.68 (2009).
15 Meshnick, S. R. Artemisinin: mechanisms of action, resistance and toxicity. International Journal for Parasitology32, 1655-1660, doi:https://doi.org/10.1016/S0020-7519(02)00194-7 (2002).
16 Steely, A. M., Willoughby, J. A., Sr., Sundar, S. N., Aivaliotis, V. I. & Firestone, G. L. Artemisinin disrupts androgen responsiveness of human prostate cancer cells by stimulating the 26S proteasome-mediated degradation of the androgen receptor protein. Anticancer Drugs28, 1018-1031, doi:10.1097/CAD.0000000000000547 (2017).
17 Chong, C. M. & Zheng, W. Artemisinin protects human retinal pigment epithelial cells from hydrogen peroxide-induced oxidative damage through activation of ERK/CREB signaling. Redox Biol9, 50-56, doi:10.1016/j.redox.2016.06.002 (2016).
18 Lin, S. P., Li, W., Winters, A., Liu, R. & Yang, S. H. Artemisinin Prevents Glutamate-Induced Neuronal Cell Death Via Akt Pathway Activation. Front Cell Neurosci12, 108, doi:10.3389/fncel.2018.00108 (2018).
19 Zheng, W. et al. Artemisinin conferred ERK mediated neuroprotection to PC12 cells and cortical neurons exposed to sodium nitroprusside-induced oxidative insult. Free Radical Biology and Medicine97, 158-167, doi:10.1016/j.freeradbiomed.2016.05.023 (2016).
20 Zhao, X. et al. Artemisinin Attenuated Hydrogen Peroxide (H2O2)-Induced Oxidative Injury in SH-SY5Y and Hippocampal Neurons via the Activation of AMPK Pathway. Int J Mol Sci20, doi:10.3390/ijms20112680 (2019).
21 Sarina et al. Induction of neurite outgrowth in PC12 cells by artemisinin through activation of ERK and p38 MAPK signaling pathways. Brain Res1490, 61-71, doi:10.1016/j.brainres.2012.10.059 (2013).
22 Zeng, Z., Xu, J. & Zheng, W. Artemisinin protects PC12 cells against beta-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway. Redox Biol12, 625-633, doi:10.1016/j.redox.2017.04.003 (2017).
23 Visser, B. J., van Vugt, M. & Grobusch, M. P. Malaria: an update on current chemotherapy. Expert Opinion on Pharmacotherapy15, 2219-2254, doi:10.1517/14656566.2014.944499 (2014).
24 Yan, F., Wang, H., Gao, Y., Xu, J. & Zheng, W. Artemisinin Protects Retinal Neuronal Cells against Oxidative Stress and Restores Rat Retinal Physiological Function from Light Exposed Damage. ACS Chemical Neuroscience8, 1713-1723, doi:10.1021/acschemneuro.7b00021 (2017).
25 Reichmann, H. et al. Unaltered Respiratory Chain Enzyme Activity and Mitochondrial DNA in Skeletal Muscle from Patients with Idiopathic Parkinson’s Syndrome. European Neurology34, 263-267, doi:10.1159/000117053 (1994).
26 Gatt, A. P. et al. Dementia in Parkinson's disease is associated with enhanced mitochondrial complex I deficiency. Mov Disord31, 352-359, doi:10.1002/mds.26513 (2016).
27 Martinet, W., Agostinis, P., Vanhoecke, B., Dewaele, M. & de Meyer, Guido R. Y. Autophagy in disease: a double-edged sword with therapeutic potential. Clinical Science116, 697-712, doi:10.1042/CS20080508 (2009).
28 Filomeni, G., De Zio, D. & Cecconi, F. Oxidative stress and autophagy: the clash between damage and metabolic needs. Cell Death Differ22, 377-388, doi:10.1038/cdd.2014.150 (2015).
29 Sun, J. & Yue, F. Suppression of REDD1 attenuates oxygen glucose deprivation/reoxygenation-evoked ischemic injury in neuron by suppressing mTOR-mediated excessive autophagy. J Cell Biochem120, 14771-14779, doi:10.1002/jcb.28737 (2019).
30 Nixon, R. A. Autophagy, amyloidogenesis and Alzheimer disease. Journal of Cell Science120, 4081, doi:10.1242/jcs.019265 (2007).
31 Isidoro, C. et al. The Role of Autophagy on the Survival of Dopamine Neurons. Curr. Top. Med. Chem.9, 869-879 (2009).
32 Pan, T., Kondo, S., Le, W. & Jankovic, J. The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease. Brain131, 1969-1978, doi:10.1093/brain/awm318 (2008).
33 Wang, X. et al. alpha-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome. Exp Ther Med19, 931-938, doi:10.3892/etm.2019.8297 (2020).