See the published version of this article at BMC Veterinary Research.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Intentional Carbofuran Poisoning in 7 dogs
Flaviu Tabaran
Universitatea de Stiinte Agricole si Medicina Veterinara din Cluj-Napoca
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5744-0451
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published version at BMC Veterinary Research.
Background: Carbofuran is a widely used broad-spectrum pesticide that, despite strict regulation and being banned for more than a decade, is still encountered in cases of intentional poisoning in dogs and wildlife. The objective of the study was to provide a complete and detailed description of the pathological, histological and toxicological findings of 7 cases of intentional carbofuran poisoning in dogs.
Results: In this retrospective study, 7 cases of carbofuran intoxication recorded from July 2015 to June 2017 were analyzed. Following complete history recording, all cases were examined by complete necropsy and histopathology. Carbofuran intoxication was confirmed in all cases by gas chromatography. The postmortem examination revealed extensive hemorrhaging and congestion located mainly within the respiratory, nervous and cardiovascular systems, accompanied by degeneration and necrosis within the lungs, heart, and kidneys.
Conclusions: Although carbamates have been banned in the European Union, carbamate poisoning is still frequently encountered, especially in wild animals. This paper will contribute to a better understanding of the occurrence and pathogenesis of acute carbofuran exposure in dogs and contribute some peculiar pathological features of this type of poisoning to the current literature.
Keywords
Carbamates, Furadan, Pathology, Veterinary forensic medicine
Figure 1
Figure 2
Figure 3
Figure 4
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
Version 7
Posted 20 Aug, 2020
Published
On 31 Aug, 2020
No community comments so far
Editorial decision: Accept
On 20 Aug, 2020
Editor assigned
On 17 Aug, 2020
Submission checks complete
On 16 Aug, 2020
Editor invited
On 16 Aug, 2020
No comments provided
Editor assigned
On 20 Jul, 2020
Editor invited
On 19 Jul, 2020
Submission checks complete
On 15 Jul, 2020
Editorial decision: Minor revision
On 15 Jul, 2020
No comments provided
Editorial decision: Minor revision
On 09 Jul, 2020
Submission checks complete
On 09 Jul, 2020
No comments provided
Editorial decision: Minor revision
On 05 Jul, 2020
Editor assigned
On 11 Jun, 2020
Submission checks complete
On 10 Jun, 2020
Editor invited
On 10 Jun, 2020
No comments provided
Editorial decision: Minor revision
On 26 May, 2020
Review #1 received
Received 18 May, 2020
Reviewer #2 agreed
On 07 May, 2020
Review #2 received
Received 07 May, 2020
Reviewer #1 agreed
On 05 May, 2020
Reviewers invited
Invitations sent on 04 May, 2020
Editor assigned
On 20 Mar, 2020
Submission checks complete
On 19 Mar, 2020
Editor invited
On 19 Mar, 2020
No comments provided
Editorial decision: Revise before sending to peer reviewers
On 05 Mar, 2020
Editor assigned
On 17 Feb, 2020
Submission checks complete
On 16 Feb, 2020
Editor invited
On 16 Feb, 2020
No comments provided
Editorial decision: Major revision
On 02 Jan, 2020
Review #2 received
Received 26 Dec, 2019
Review #1 received
Received 23 Dec, 2019
Reviewer #2 agreed
On 16 Dec, 2019
Reviewer #1 agreed
On 13 Dec, 2019
Reviewers invited
Invitations sent on 12 Dec, 2019
Editor assigned
On 06 Dec, 2019
First submitted
On 05 Dec, 2019
Submission checks complete
On 05 Dec, 2019
Editor invited
On 05 Dec, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Small Animal Medicine
Learn more about our company.
This preprint is under consideration at BMC Veterinary Research. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Intentional Carbofuran Poisoning in 7 dogs
Flaviu Tabaran
Universitatea de Stiinte Agricole si Medicina Veterinara din Cluj-Napoca
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5744-0451
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
Version 7
Posted 20 Aug, 2020
Published
On 31 Aug, 2020
No community comments so far
Editorial decision: Accept
On 20 Aug, 2020
Editor assigned
On 17 Aug, 2020
Submission checks complete
On 16 Aug, 2020
Editor invited
On 16 Aug, 2020
No comments provided
Editor assigned
On 20 Jul, 2020
Editor invited
On 19 Jul, 2020
Submission checks complete
On 15 Jul, 2020
Editorial decision: Minor revision
On 15 Jul, 2020
No comments provided
Editorial decision: Minor revision
On 09 Jul, 2020
Submission checks complete
On 09 Jul, 2020
No comments provided
Editorial decision: Minor revision
On 05 Jul, 2020
Editor assigned
On 11 Jun, 2020
Submission checks complete
On 10 Jun, 2020
Editor invited
On 10 Jun, 2020
No comments provided
Editorial decision: Minor revision
On 26 May, 2020
Review #1 received
Received 18 May, 2020
Reviewer #2 agreed
On 07 May, 2020
Review #2 received
Received 07 May, 2020
Reviewer #1 agreed
On 05 May, 2020
Reviewers invited
Invitations sent on 04 May, 2020
Editor assigned
On 20 Mar, 2020
Submission checks complete
On 19 Mar, 2020
Editor invited
On 19 Mar, 2020
No comments provided
Editorial decision: Revise before sending to peer reviewers
On 05 Mar, 2020
Editor assigned
On 17 Feb, 2020
Submission checks complete
On 16 Feb, 2020
Editor invited
On 16 Feb, 2020
No comments provided
Editorial decision: Major revision
On 02 Jan, 2020
Review #2 received
Received 26 Dec, 2019
Review #1 received
Received 23 Dec, 2019
Reviewer #2 agreed
On 16 Dec, 2019
Reviewer #1 agreed
On 13 Dec, 2019
Reviewers invited
Invitations sent on 12 Dec, 2019
Editor assigned
On 06 Dec, 2019
First submitted
On 05 Dec, 2019
Submission checks complete
On 05 Dec, 2019
Editor invited
On 05 Dec, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Small Animal Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published version at BMC Veterinary Research.
Background: Carbofuran is a widely used broad-spectrum pesticide that, despite strict regulation and being banned for more than a decade, is still encountered in cases of intentional poisoning in dogs and wildlife. The objective of the study was to provide a complete and detailed description of the pathological, histological and toxicological findings of 7 cases of intentional carbofuran poisoning in dogs.
Results: In this retrospective study, 7 cases of carbofuran intoxication recorded from July 2015 to June 2017 were analyzed. Following complete history recording, all cases were examined by complete necropsy and histopathology. Carbofuran intoxication was confirmed in all cases by gas chromatography. The postmortem examination revealed extensive hemorrhaging and congestion located mainly within the respiratory, nervous and cardiovascular systems, accompanied by degeneration and necrosis within the lungs, heart, and kidneys.
Conclusions: Although carbamates have been banned in the European Union, carbamate poisoning is still frequently encountered, especially in wild animals. This paper will contribute to a better understanding of the occurrence and pathogenesis of acute carbofuran exposure in dogs and contribute some peculiar pathological features of this type of poisoning to the current literature.
Figure 1
Figure 2
Figure 3
Figure 4