DOI: https://doi.org/10.21203/rs.3.rs-931342/v1
Objective: To explore the clinical efficacy of moxibustion to the treatment of allergic rhinitis.
Methods: The randomized controlled trials (RCTs) of moxibustion to the treatment of AR was retrieved who search alone by two researchers in 31 August , 2021. The final 24 articles were retained by two other researchers based on inclusion criteria and exclusion criteria.
Results: Moxibustion is effective in the treatment of AR among which heat-sensitive moxibustion has the most significant effect (P<0.00001) , followed by governor vessel moxibustion(P<0.0008), again is thunder fire moxibustion(P=0.003), the worst effect was herb-partitioned moxibustion(P=0.70). In the symptom subgroup comparison, moxibustion is effective in controlling sneezing(P=0.03) and runny nose(P=0.05), and the best is heat-sensitive moxibustion(P<0.00001) whether it is sneezing, nasal congestion, runny nose and nasal itching is the best. In the follow-up subgroup analysis, the efficacy of the follow-up of 3 months and 1 month was the same (P<0.00001) that the long-term efficacy of moxibustion for AR was better. In the IgE subgroup, moxibustion in the treatment of AR can make serum IgE down both after treatment(P<0.00001) and 6 months(P<0.0001).
Conclusion: Moxibustion treatment of AR can not only improve the clinical symptoms of patients and control the attack, but also has a good long-term effect to prevent recurrence. Moxibustion treatment of AR heat-sensitive moxibustion effect is the best. Due to the limitations of this study, large-scale clinical high-quality randomized, a multi-center, controlled trial clinical study is needed in order to further verify our conclusions.