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Research article
Ozgur Erdogan
Health Sciences University Haydarpasa Numune Training and Research Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0002-6703-3881
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Vascular clamp application is widely used in visceral organ surgery to ensure bleeding control. This raises the question: why not use clamping in tumor resection or revision surgery where not suitable for tourniquet. This experimental animal study aimed to compare the arterial clamp and tourniquet applications regarding their histologic effect and also inflammatory response at molecular level, on the artery, vein, nerve and muscle tissues.
Methods: Twenty-one rabbits were divided into three groups (group I: proximal femoral artery clamp; group II: proximal thigh tourniquet, and group III: control group). In the clamp group, the common femoral artery was clamped with a microvascular clamp for 2 hours. In the tourniquet group, a 12-inch cuff was applied to the proximal thigh for 2 hours with 200 mmHg. The common femoral artery and vein, femoral nerve, rectus femoris, and tibialis anterior muscles were excised and analysed in all groups.
Results: Artery and vein total injury scores were higher in the clamp and tourniquet groups relative to the control group (p≤0.001 and p=0.007, respectively). No statistical difference was found between the clamp and tourniquet groups in terms of arterial, vein, muscle and nerve injury.
Conclusions: This experimental study can give an idea that arterial clamp application can be performed with the help of a vascular surgeon in hemorrhagic limb surgeries where not suitable for tourniquet application, resulting in close to tourniquet vessel injury rates but without tourniquet related complications.
Keywords
tourniquet, clamp, hemorragia, artery, vein, injury
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A new preprint design is coming!
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research article
Ozgur Erdogan
Health Sciences University Haydarpasa Numune Training and Research Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0002-6703-3881
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 21 Oct, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedic Surgery
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Vascular clamp application is widely used in visceral organ surgery to ensure bleeding control. This raises the question: why not use clamping in tumor resection or revision surgery where not suitable for tourniquet. This experimental animal study aimed to compare the arterial clamp and tourniquet applications regarding their histologic effect and also inflammatory response at molecular level, on the artery, vein, nerve and muscle tissues.
Methods: Twenty-one rabbits were divided into three groups (group I: proximal femoral artery clamp; group II: proximal thigh tourniquet, and group III: control group). In the clamp group, the common femoral artery was clamped with a microvascular clamp for 2 hours. In the tourniquet group, a 12-inch cuff was applied to the proximal thigh for 2 hours with 200 mmHg. The common femoral artery and vein, femoral nerve, rectus femoris, and tibialis anterior muscles were excised and analysed in all groups.
Results: Artery and vein total injury scores were higher in the clamp and tourniquet groups relative to the control group (p≤0.001 and p=0.007, respectively). No statistical difference was found between the clamp and tourniquet groups in terms of arterial, vein, muscle and nerve injury.
Conclusions: This experimental study can give an idea that arterial clamp application can be performed with the help of a vascular surgeon in hemorrhagic limb surgeries where not suitable for tourniquet application, resulting in close to tourniquet vessel injury rates but without tourniquet related complications.
Figure 1
Figure 2
Figure 3
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