Genotoxicity and Gene Expression in the Rat Lung Tissue Following Instillation and Inhalation of Different Variants of Amorphous Silica Nanomaterials (aSiO2 NMs)

doi:10.21203/rs.3.rs-96206/v1

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Fátima Brandão, Carla Costa, Maria João Bessa, Elise Dumortier, Florence Debacq-Chainiaux, Roland Hubaux, Michel Salmon, Julie Laloy, Miruna S. Stan, Anca Hermenean, Sami Gharbia, Anca Dinischiotu, Anne Bannuscher, Bryan Hellack, Andrea Haase, Sónia Fraga, João Paulo Teixeira

Fátima Brandão

National Institute of Health Doctor Ricardo Jorge: Instituto Nacional de Saude Doutor Ricardo Jorge

Carla Costa

National Institute of Health Doctor Ricardo Jorge: Instituto Nacional de Saude Doutor Ricardo Jorge

Maria João Bessa

Institute of Public Health of the University of Porto

Elise Dumortier

Université de Namur: Universite de Namur

Florence Debacq-Chainiaux

University of Namur: Universite de Namur

Roland Hubaux

StratiCELL

Michel Salmon

StratiCELL

Julie Laloy

University of Namur: Universite de Namur

Miruna S. Stan

University of Bucharest: Universitatea din Bucuresti

Anca Hermenean

Vasile Goldis University of Arad Faculty of Medicine: Universitatea de Vest Vasile Goldis din Arad Facultatea de Medicina

Sami Gharbia

Vasile Goldis University of Arad Faculty of Medicine: Universitatea de Vest Vasile Goldis din Arad Facultatea de Medicina

Anca Dinischiotu

University of Bucharest: Universitatea din Bucuresti

Anne Bannuscher

University of Fribourg: Universite de Fribourg

Bryan Hellack

UBA: Umweltbundesamt

Andrea Haase

BfR: Bundesinstitut fur Risikobewertung

Sónia Fraga

Instituto Nacional de Saude Doutor Ricardo Jorge IP

Corresponding Author

ORCiD: https://orcid.org/0000-0001-9386-2336

João Paulo Teixeira

National Institute of Health Doctor Ricardo Jorge: Instituto Nacional de Saude Doutor Ricardo Jorge

DOI:

10.21203/rs.3.rs-96206/v1

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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.

Fátima Brandão, Carla Costa, Maria João Bessa, Elise Dumortier, Florence Debacq-Chainiaux, Roland Hubaux, Michel Salmon, Julie Laloy, Miruna S. Stan, Anca Hermenean, Sami Gharbia, Anca Dinischiotu, Anne Bannuscher, Bryan Hellack, Andrea Haase, Sónia Fraga, João Paulo Teixeira

Fátima Brandão

National Institute of Health Doctor Ricardo Jorge: Instituto Nacional de Saude Doutor Ricardo Jorge

Carla Costa

National Institute of Health Doctor Ricardo Jorge: Instituto Nacional de Saude Doutor Ricardo Jorge

Maria João Bessa

Institute of Public Health of the University of Porto

Elise Dumortier

Université de Namur: Universite de Namur

Florence Debacq-Chainiaux

University of Namur: Universite de Namur

Roland Hubaux

StratiCELL

Michel Salmon

StratiCELL

Julie Laloy

University of Namur: Universite de Namur

Miruna S. Stan

University of Bucharest: Universitatea din Bucuresti

Anca Hermenean

Vasile Goldis University of Arad Faculty of Medicine: Universitatea de Vest Vasile Goldis din Arad Facultatea de Medicina

Sami Gharbia

Vasile Goldis University of Arad Faculty of Medicine: Universitatea de Vest Vasile Goldis din Arad Facultatea de Medicina

Anca Dinischiotu

University of Bucharest: Universitatea din Bucuresti

Anne Bannuscher

University of Fribourg: Universite de Fribourg

Bryan Hellack

UBA: Umweltbundesamt

Andrea Haase

BfR: Bundesinstitut fur Risikobewertung

Sónia Fraga

Instituto Nacional de Saude Doutor Ricardo Jorge IP

Corresponding Author

ORCiD: https://orcid.org/0000-0001-9386-2336

João Paulo Teixeira

National Institute of Health Doctor Ricardo Jorge: Instituto Nacional de Saude Doutor Ricardo Jorge

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Prescreen

History

CURRENT STATUS: Posted

View the published article at Nanomaterials.

Version 1

Posted 27 Oct, 2020

No community comments so far

MetricsComments: 0PDF Downloads: ...HTML Views: ...

A new preprint design is coming!

We have improved readability, clarity, accessibility, and opportunities for engagement.

Fátima Brandão, Carla Costa, Maria João Bessa, Elise Dumortier, Florence Debacq-Chainiaux, Roland Hubaux, Michel Salmon, Julie Laloy, Miruna S. Stan, Anca Hermenean, Sami Gharbia, Anca Dinischiotu, Anne Bannuscher, Bryan Hellack, Andrea Haase, Sónia Fraga, João Paulo Teixeira

Fátima Brandão

National Institute of Health Doctor Ricardo Jorge: Instituto Nacional de Saude Doutor Ricardo Jorge

Carla Costa

National Institute of Health Doctor Ricardo Jorge: Instituto Nacional de Saude Doutor Ricardo Jorge

Maria João Bessa

Institute of Public Health of the University of Porto

Elise Dumortier

Université de Namur: Universite de Namur

Florence Debacq-Chainiaux

University of Namur: Universite de Namur

Roland Hubaux

StratiCELL

Michel Salmon

StratiCELL

Julie Laloy

University of Namur: Universite de Namur

Miruna S. Stan

University of Bucharest: Universitatea din Bucuresti

Anca Hermenean

Vasile Goldis University of Arad Faculty of Medicine: Universitatea de Vest Vasile Goldis din Arad Facultatea de Medicina

Sami Gharbia

Vasile Goldis University of Arad Faculty of Medicine: Universitatea de Vest Vasile Goldis din Arad Facultatea de Medicina

Anca Dinischiotu

University of Bucharest: Universitatea din Bucuresti

Anne Bannuscher

University of Fribourg: Universite de Fribourg

Bryan Hellack

UBA: Umweltbundesamt

Andrea Haase

BfR: Bundesinstitut fur Risikobewertung

Sónia Fraga

Instituto Nacional de Saude Doutor Ricardo Jorge IP

Corresponding Author

ORCiD: https://orcid.org/0000-0001-9386-2336

João Paulo Teixeira

National Institute of Health Doctor Ricardo Jorge: Instituto Nacional de Saude Doutor Ricardo Jorge

DOI:

10.21203/rs.3.rs-96206/v1

Download PDF

License:

This work is licensed under a CC BY 4.0 License. Read Full License

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CURRENT STATUS: Posted

View the published article at Nanomaterials.

Version 1

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Comments: 0

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Learn more about our company.

A new preprint design is coming!

We have improved readability, clarity, accessibility, and opportunities for engagement.

Fátima Brandão, Carla Costa, Maria João Bessa, Elise Dumortier, Florence Debacq-Chainiaux, Roland Hubaux, Michel Salmon, Julie Laloy, Miruna S. Stan, Anca Hermenean, Sami Gharbia, Anca Dinischiotu, Anne Bannuscher, Bryan Hellack, Andrea Haase, Sónia Fraga, João Paulo Teixeira

Fátima Brandão

National Institute of Health Doctor Ricardo Jorge: Instituto Nacional de Saude Doutor Ricardo Jorge

Carla Costa

National Institute of Health Doctor Ricardo Jorge: Instituto Nacional de Saude Doutor Ricardo Jorge

Maria João Bessa

Institute of Public Health of the University of Porto

Elise Dumortier

Université de Namur: Universite de Namur

Florence Debacq-Chainiaux

University of Namur: Universite de Namur

Roland Hubaux

StratiCELL

Michel Salmon