Background: Many patients with end-stage renal disease (ESRD) have poor physical and mental health, little is known about these health domains in individuals with advanced chronic kidney disease (CKD). The study aimed to study how symptoms, depression, and health-related quality of life (HRQoL) differed between ESRD and CKD patients.
Methodology: Patients with ESRD and those with advanced CKD are included in the study. The Morisky Lewis Greens Adherence measures, Hamilton Depression Rating Scale, and KDQOL-SF-36 were used to assess patients' adherence, depression, and HRQoL, and these health domains were compared between patient groups.
Results: A total of 314 patients participated in the study, the mean age of participants was 54.64±15.33. Hypertension and diabetes remained the predominant comorbid conditions with prevalence rates of 64.2% and 74.6%, respectively which is significantly higher level of depression observed , which also deteriorates follow-up periods in both groups of patients. The anemic condition remained the major problem among patients with ESRD. The results show thay the overall HRQoL domain and scale parameters were deteriorating the follow-up period. Scores on the SF-36 Physical Component Summary and the SF-36 Mental Component Summary were similar.
Conclusions: Patients with ESRD and advanced CKD have similar symptom burdens, depression rates, and poor HRQoL. Given the well-known impairments in both patient groups, the findings of this study highlight the significant decline in the physical and psychological well-being of CKD patients.