1. Aravind, A., A.R. Ravula, N. Chandra, and B.J. Pfister, Behavioral Deficits in Animal Models of Blast Traumatic Brain Injury. Frontiers in Neurology, 2020. 11(990).
2. Kuriakose, M., D. Younger, A.R. Ravula, E. Alay, K.V. Rama Rao, and N. Chandra, Synergistic Role of Oxidative Stress and Blood-Brain Barrier Permeability as Injury Mechanisms in the Acute Pathophysiology of Blast-induced Neurotrauma. Sci Rep, 2019. 9(1): p. 7717.
3. Nyanzu, M., F. Siaw-Debrah, H. Ni, Z. Xu, H. Wang, X. Lin, Q. Zhuge, and L. Huang, Improving on Laboratory Traumatic Brain Injury Models to Achieve Better Results. Int J Med Sci, 2017. 14(5): p. 494-505.
4. Rana, P., K.V. Rama Rao, A. Ravula, R. Trivedi, M. D'Souza, A.K. Singh, R.K. Gupta, and N. Chandra, Oxidative stress contributes to cerebral metabolomic profile changes in animal model of blast-induced traumatic brain injury. Metabolomics, 2020. 16(3): p. 39.
5. Lee, J.J., D.J. Segar, J.F. Morrison, W.M. Mangham, S. Lee, and W.F. Asaad, Subdural hematoma as a major determinant of short-term outcomes in traumatic brain injury. J Neurosurg, 2018. 128(1): p. 236-249.
6. Perel, P., I. Roberts, O. Bouamra, M. Woodford, J. Mooney, and F. Lecky, Intracranial bleeding in patients with traumatic brain injury: A prognostic study. BMC Emergency Medicine, 2009. 9(1): p. 15.
7. Schweitzer, A.D., S.N. Niogi, C.T. Whitlow, and A.J. Tsiouris, Traumatic Brain Injury: Imaging Patterns and Complications. RadioGraphics, 2019. 39(6): p. 1571-1595.
8. Weil, Z.M., J.D. Corrigan, and K. Karelina, Alcohol Use Disorder and Traumatic Brain Injury. Alcohol Res, 2018. 39(2): p. 171-180.
9. Teng SX, M.P., Acute Alcohol Intoxication Prolongs Neuroinflammation without Exacerbating Neurobehavioral Dysfunction following Mild Traumatic Brain Injury. Journal of Neurotrauma, 2014. 31(4): p. 378-386.
10. Lowe, P.P., C. Morel, A. Ambade, A. Iracheta-Vellve, E. Kwiatkowski, A. Satishchandran, I. Furi, Y. Cho, B. Gyongyosi, D. Catalano, E. Lefebvre, L. Fischer, S. Seyedkazemi, D.P. Schafer, and G. Szabo, Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations. J Neuroinflammation, 2020. 17(1): p. 296.
11. Smith, S., K. Fair, A. Goodman, J. Watson, C. Dodgion, and M. Schreiber, Consumption of alcohol leads to platelet inhibition in men. The American Journal of Surgery, 2019. 217(5): p. 868-872.
12. Ma, X., Y. Cheng, R. Garcia, and J. Haorah, Hemorrhage Associated Mechanisms of Neuroinflammation in Experimental Traumatic Brain Injury. J Neuroimmune Pharmacol, 2020. 15(2): p. 181-195.
13. Ma, X., A. Aravind, B.J. Pfister, N. Chandra, and J. Haorah, Animal Models of Traumatic Brain Injury and Assessment of Injury Severity. Mol Neurobiol, 2019. 56(8): p. 5332-5345.
14. East, J.M., J. Viau-Lapointe, and V.A. McCredie, Transfusion practices in traumatic brain injury. Curr Opin Anaesthesiol, 2018. 31(2): p. 219-226.
15. Stolla, M., F. Zhang, M.R. Meyer, J. Zhang, and J.-F. Dong, Current state of transfusion in traumatic brain injury and associated coagulopathy. Transfusion, 2019. 59(S2): p. 1522-1528.
16. Salim, A., P. Hadjizacharia, J. DuBose, C. Brown, K. Inaba, L. Chan, and D.R. Margulies, Role of anemia in traumatic brain injury. J Am Coll Surg, 2008. 207(3): p. 398-406.
17. Daglas, M. and P.A. Adlard, The Involvement of Iron in Traumatic Brain Injury and Neurodegenerative Disease. Front Neurosci, 2018. 12: p. 981.
18. Magnani, M., V. Stocchi, L. Cucchiarini, L. Chiarantini, and G. Fornaini, Red blood cell phagocytosis and lysis following oxidative damage by phenylhydrazine. Cell Biochem Funct, 1986. 4(4): p. 263-9.
19. Wimmer, I., C. Scharler, T. Kadowaki, S. Hillebrand, B. Scheiber-Mojdehkar, S. Ueda, M. Bradl, T. Berger, H. Lassmann, and S. Hametner, Iron accumulation in the choroid plexus, ependymal cells and CNS parenchyma in a rat strain with low-grade haemolysis of fragile macrocytic red blood cells. Brain Pathol, 2021. 31(2): p. 333-345.
20. Izatt, R.M., G.D. Watt, C.H. Bartholomew, and J.J. Christensen, Calorimetric study of Prussian blue and Turnbull's blue formation. Inorganic Chemistry, 1970. 9(9): p. 2019-2021.
21. Dev, S. and J.L. Babitt, Overview of iron metabolism in health and disease. Hemodialysis International, 2017. 21(S1): p. S6-S20.
22. Russell, N.H., R.T. Black, N.N. Lee, A.E. Doperalski, T.M. Reeves, and L.L. Phillips, Time-dependent hemeoxygenase-1, lipocalin-2 and ferritin induction after non-contusion traumatic brain injury. Brain Research, 2019. 1725: p. 146466.
23. Donat, C.K., G. Scott, S.M. Gentleman, and M. Sastre, Microglial Activation in Traumatic Brain Injury. Frontiers in Aging Neuroscience, 2017. 9(208).
24. Murugan, M., A. Ravula, A. Gandhi, G. Vegunta, S. Mukkamalla, W. Mujib, and N. Chandra, Chemokine signaling mediated monocyte infiltration affects anxiety-like behavior following blast injury. Brain, Behavior, and Immunity, 2020. 88: p. 340-352.
25. Alikunju, S., P.M. Abdul Muneer, Y. Zhang, A.M. Szlachetka, and J. Haorah, The inflammatory footprints of alcohol-induced oxidative damage in neurovascular components. Brain, Behavior, and Immunity, 2011. 25: p. S129-S136.
26. Cheng, Y., X. Ma, K.D. Belfield, and J. Haorah, Biphasic Effects of Ethanol Exposure on Waste Metabolites Clearance in the CNS. Molecular Neurobiology, 2021.
27. Muneer, P.M.A., S. Alikunju, A.M. Szlachetka, and J. Haorah, The Mechanisms of Cerebral Vascular Dysfunction and Neuroinflammation by MMP-Mediated Degradation of VEGFR-2 in Alcohol Ingestion. Arteriosclerosis, Thrombosis, and Vascular Biology, 2012. 32(5): p. 1167-1177.
28. Sarkar, B., X. Ma, A. Agas, Z. Siddiqui, P. Iglesias-Montoro, P.K. Nguyen, K.K. Kim, J. Haorah, and V.A. Kumar, In vivo neuroprotective effect of a self-assembled peptide hydrogel. Chemical Engineering Journal, 2021. 408: p. 127295.
29. Blomster, L.V., G.J. Cowin, N.D. Kurniawan, and M.J. Ruitenberg, Detection of endogenous iron deposits in the injured mouse spinal cord through high-resolution ex vivo and in vivo MRI. NMR Biomed, 2013. 26(2): p. 141-50.
30. Crowe, A., W. Zheng, J. Miller, S. Pahwa, K. Alam, K.-M. Fung, E. Rubin, F. Yin, K. Ding, and W. Yue, Characterization of Plasma Membrane Localization and Phosphorylation Status of Organic Anion Transporting Polypeptide (OATP) 1B1 c.521 T>C Nonsynonymous Single-Nucleotide Polymorphism. Pharmaceutical research, 2019. 36(7): p. 101-101.
31. Crowe, A.R. and W. Yue, Semi-quantitative Determination of Protein Expression using Immunohistochemistry Staining and Analysis: An Integrated Protocol. Bio-protocol, 2019. 9(24): p. e3465.
32. Dietrich, W.D., O. Alonso, R. Busto, R. Prado, S. Dewanjee, M.K. Dewanjee, and M.D. Ginsberg, Widespread hemodynamic depression and focal platelet accumulation after fluid percussion brain injury: a double-label autoradiographic study in rats. J Cereb Blood Flow Metab, 1996. 16(3): p. 481-9.
33. McKee, A.C. and D.H. Daneshvar, The neuropathology of traumatic brain injury. Handbook of clinical neurology, 2015. 127: p. 45-66.
34. Weisel, J.W. and R.I. Litvinov, Red blood cells: the forgotten player in hemostasis and thrombosis. Journal of Thrombosis and Haemostasis, 2019. 17(2): p. 271-282.
35. Cheng, Y. and J. Haorah, How does the brain remove its waste metabolites from within? Int J Physiol Pathophysiol Pharmacol, 2019. 11(6): p. 238-249.
36. Imai, T., S. Iwata, T. Hirayama, H. Nagasawa, S. Nakamura, M. Shimazawa, and H. Hara, Intracellular Fe(2+) accumulation in endothelial cells and pericytes induces blood-brain barrier dysfunction in secondary brain injury after brain hemorrhage. Sci Rep, 2019. 9(1): p. 6228.
37. Eid, R., N.T. Arab, and M.T. Greenwood, Iron mediated toxicity and programmed cell death: A review and a re-examination of existing paradigms. Biochim Biophys Acta Mol Cell Res, 2017. 1864(2): p. 399-430.
38. Balter, L.J.T., J.A. Bosch, S. Aldred, M.T. Drayson, J.J.C.S. Veldhuijzen van Zanten, S. Higgs, J.E. Raymond, and A. Mazaheri, Selective effects of acute low-grade inflammation on human visual attention. NeuroImage, 2019. 202: p. 116098.
39. Kim, K.W., C.S. Yoon, Y.C. Kim, and H. Oh, Desoxo-narchinol A and Narchinol B Isolated from Nardostachys jatamansi Exert Anti-neuroinflammatory Effects by Up-regulating of Nuclear Transcription Factor Erythroid-2-Related Factor 2/Heme Oxygenase-1 Signaling. Neurotox Res, 2019. 35(1): p. 230-243.
40. Shin, M.K., S.I. Kim, S.J. Kim, S.Y. Park, Y.H. Hyun, Y. Lee, K.E. Lee, S.S. Han, D.P. Jang, Y.B. Kim, Z.H. Cho, I. So, and G.M. Spinks, Controlled magnetic nanofiber hydrogels by clustering ferritin. Langmuir, 2008. 24(21): p. 12107-11.
41. Arosio, P., L. Elia, and M. Poli, Ferritin, cellular iron storage and regulation. IUBMB Life, 2017. 69(6): p. 414-422.
42. Li Volti, G., F. Galvano, A. Frigiola, S. Guccione, C. Di Giacomo, S. Forte, G. Tringali, M. Caruso, O.A. Adekoya, and D. Gazzolo, Potential immunoregulatory role of heme oxygenase-1 in human milk: a combined biochemical and molecular modeling approach. J Nutr Biochem, 2010. 21(9): p. 865-71.
43. Moschen, A.R., T.E. Adolph, R.R. Gerner, V. Wieser, and H. Tilg, Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation. Trends Endocrinol Metab, 2017. 28(5): p. 388-397.
44. Tran, T.N., S.K. Eubanks, K.J. Schaffer, C.Y.J. Zhou, and M.C. Linder, Secretion of Ferritin by Rat Hepatoma Cells and Its Regulation by Inflammatory Cytokines and Iron. Blood, 1997. 90(12): p. 4979-4986.
45. Jin, Z., K.E. Kim, H.J. Shin, E.A. Jeong, K.A. Park, J.Y. Lee, H.S. An, E.B. Choi, J.H. Jeong, W. Kwak, and G.S. Roh, Hippocampal Lipocalin 2 Is Associated With Neuroinflammation and Iron-Related Oxidative Stress in ob/ob Mice. J Neuropathol Exp Neurol, 2020. 79(5): p. 530-541.
46. Morita, A., A. Jullienne, A. Salehi, M. Hamer, E. Javadi, Y. Alsarraj, J. Tang, J.H. Zhang, W.J. Pearce, and A. Obenaus, Temporal evolution of heme oxygenase-1 expression in reactive astrocytes and microglia in response to traumatic brain injury. Brain Hemorrhages, 2020. 1(1): p. 65-74.
47. McIntosh, A., V. Mela, C. Harty, A.M. Minogue, D.A. Costello, C. Kerskens, and M.A. Lynch, Iron accumulation in microglia triggers a cascade of events that leads to altered metabolism and compromised function in APP/PS1 mice. Brain Pathol, 2019. 29(5): p. 606-621.
48. Mairuae, N., J.R. Connor, and P. Cheepsunthorn, Increased cellular iron levels affect matrix metalloproteinase expression and phagocytosis in activated microglia. Neurosci Lett, 2011. 500(1): p. 36-40.
49. Lan, X., X. Han, Q. Li, Q.W. Yang, and J. Wang, Modulators of microglial activation and polarization after intracerebral haemorrhage. Nat Rev Neurol, 2017. 13(7): p. 420-433.
50. Loane, D.J. and A. Kumar, Microglia in the TBI brain: The good, the bad, and the dysregulated. Experimental Neurology, 2016. 275: p. 316-327.
51. Walter, T.J., R.P. Vetreno, and F.T. Crews, Alcohol and Stress Activation of Microglia and Neurons: Brain Regional Effects. Alcohol Clin Exp Res, 2017. 41(12): p. 2066-2081.
52. Fernandez-Lizarbe, S., M. Pascual, and C. Guerri, Critical Role of TLR4 Response in the Activation of Microglia Induced by Ethanol. The Journal of Immunology, 2009. 183(7): p. 4733-4744.
53. Mishra, V., A. Agas, H. Schuetz, J. Kalluru, and J. Haorah, Alcohol induces programmed death receptor-1 and programmed death-ligand-1 differentially in neuroimmune cells. Alcohol, 2020. 86: p. 65-74.
54. Zhao, Y.-N., F. Wang, Y.-X. Fan, G.-F. Ping, J.-Y. Yang, and C.-F. Wu, Activated microglia are implicated in cognitive deficits, neuronal death, and successful recovery following intermittent ethanol exposure. Behavioural Brain Research, 2013. 236: p. 270-282.
55. Peng, H. and K. Nixon, Microglia Phenotypes Following the Induction of Alcohol Dependence in Adolescent Rats. Alcohol Clin Exp Res, 2021. 45(1): p. 105-116.
56. Klei, T.R., S.M. Meinderts, T.K. van den Berg, and R. van Bruggen, From the Cradle to the Grave: The Role of Macrophages in Erythropoiesis and Erythrophagocytosis. Front Immunol, 2017. 8: p. 73.
57. Li, J., F. Cao, H.L. Yin, Z.J. Huang, Z.T. Lin, N. Mao, B. Sun, and G. Wang, Ferroptosis: past, present and future. Cell Death Dis, 2020. 11(2): p. 88.
58. Abrahao, K.P., A.G. Salinas, and D.M. Lovinger, Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits. Neuron, 2017. 96(6): p. 1223-1238.
59. Ioannou, G.N., J.A. Dominitz, N.S. Weiss, P.J. Heagerty, and K.V. Kowdley, The effect of alcohol consumption on the prevalence of iron overload, iron deficiency, and iron deficiency anemia. Gastroenterology, 2004. 126(5): p. 1293-301.
60. Kärkkäinen, J.M., S. Miilunpohja, T. Rantanen, J.M. Koskela, J. Jyrkkä, J. Hartikainen, and H. Paajanen, Alcohol Abuse Increases Rebleeding Risk and Mortality in Patients with Non-variceal Upper Gastrointestinal Bleeding. Dig Dis Sci, 2015. 60(12): p. 3707-15.
61. Agnieszka, A., R. Arun Reddy, M. Xiaotang, C. Yiming, D.B. Kevin, and H. James, Research Square, 2022.